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Urmila K.,LLRM Medical College Meerut | Uzma K.,LLRM Medical College | Manjul B.,P.A. College
Indian Journal of Public Health Research and Development | Year: 2013

Objective: To study the prevalence of asymptomatic bacteriuria(ABU) in pregnant women& its association with pregnancy outcome. Method: A Descriptive Study (Cross Section) was done in 800 antenatal women up to 28 weeks during the year2009-2010.Urine culture was done after recording patient obstetrical, personal, past history, clinical examination. Out of which 48 (Group-A) found having ABU (>1 × 105 CFU/ml), while 752(Group-B) were not having any bacteriuria. Both the Groups were further followed monthly up to delivery. At the time of delivery perinatal outcome recorded. Result: Prevalence of ABU is 6% (48/752). E.coli (75%) was common pathogen followed by Staph.saprophyticus, Klebseilla. It is associated with increased risk of Symptomatic UTI as 12.5%bacteruric& 2.93%non-bacteruric women develop symptomatic UTI(p<0.001). ABU was found to be associated with Preterm Labour as 20.83% bacteruric & 4.8% non-bacteriuric women have preterm labour(p<0.044). It is also associated with Low Birth Weight babies as 16.67% in bacteriuric & 6.12%nonbacteriuric women have LBW babies(p<0.049). Conclusion: ABU is a common infection during pregnancy & it increases the risk of Preterm birth, Low birth weight babies & Symptomatic UTI.

Mithal C.,LLRM Medical College Meerut
Nepalese journal of ophthalmology : a biannual peer-reviewed academic journal of the Nepal Ophthalmic Society : NEPJOPH | Year: 2012

The manual small incision cataract surgery (MSICS) is the surgery of choice in countries with a huge back-log of cataract blindness. To evaluate the outcome of manual small incision cataract surgery (MSICS) under topical anesthesia with lignocaine 2 % jelly. This study was a prospective interventional case series. One hundred and twenty eight patients of senile cataract were operated by MSICS under topical anesthesia using lignocaine 2% jelly. No intra-cameral anesthesia was used. The patients and the single operating surgeon were given a questionnaire to evaluate their experience in terms of pain, surgical experience and complications. The mean pain score was 0.82 (SD +/- 0.97). Seventy-one patients (55.4 %) had a pain score of zero, that is, no pain. One hundred and twenty one patients (94.5 %) had a score of 3 or less, that is, mild to none pain. All the surgeries except two were complication- free and the surgeon's experience was favorable in terms of the patient's cooperation, anterior chamber stability, difficulty, and complications. MSICS can be performed under topical anesthesia with lignocaine jelly, which makes the surgery patient-friendly, without compromising the outcome. © NEPjOPH.

Rajput C.S.,LLRM Medical College Meerut | Kumar S.,LLRM Medical College Meerut | Kumar A.,LLRM Medical College Meerut
International Journal of ChemTech Research | Year: 2010

3-(2'-substitutedarylidineimino-1',3'-thiazol-4'-yl)amino-2-methyl-monosubstituted quinazolin-4(3H)-ones (4a-d), 3-[2'-(3'-chloro-2'-oxo-4'-substitutedaryl-1'-zetidinyl)-1'-,3'-thiazol-4'-yl]-amino-2- methylmono substituted quinazolin-4-(3H)-ones (5a-d), and 3-[2'-(substitutedaryl-4'-thiazolidinon-3'-yl)-1',3'-thiazol-4'-yl]-amino-2-methylmono substitutedquinazolin-4(3H)-ones (6a-d) were synthesized in present study. All the compounds have been screened for their anti-fungal activity. The structure of all by compounds was confirmed by their analytical(C, H, N) and spectral (IR, 1H NMR) data.

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