Entity

Time filter

Source Type

Apeldoorn, Netherlands

Yagur-Kroll S.,Hebrew University of Jerusalem | Schreuder E.,LioniX | Ingham C.J.,MicroDish BV | Heideman R.,LioniX | And 2 more authors.
Biosensors and Bioelectronics | Year: 2014

The use of live bacterial reporters as sensing entities in whole-cell biosensors allows the investigation of the biological effects of a tested sample, as well as the bioavailability of its components. Here we present a proof of concept for a new design for online continuous water monitoring flow-cell biosensor, incorporating recombinant reporter bacteria, engineered to generate an optical signal (fluorescent or bioluminescent) in the presence of the target compound(s). At the heart of the flow-cell is a disposable chip made of porous aluminum oxide (PAO), which retains the sensor microorganisms on its rigid planar surface, while its high porosity allows an undisturbed access both to the sample and to essential nutrients. The ability of the bacterial reporters to detect model toxic chemicals was first demonstrated using a "naked" PAO chip placed on solid agar, and later in a chip encased in a specially designed flow-through configuration which enables continuous on-line monitoring. The applicability of the PAO chip to simultaneous online detection of diverse groups of chemicals was demonstrated by the incorporation of a 6-member sensor array into the flow-through chip. The selective response of the array was also confirmed in spiked municipal wastewater effluents. Sensing activity was retained by the bacteria after 12-weeks storage of freeze-dried biochips, demonstrating the biochip potential as a simple minimal maintenance "plug-in" cartridge. This low-cost and easy to handle PAO-based flow-cell biosensor may serve as a basis for a future platform for water quality monitoring. © 2014 Elsevier B.V. Source


Yu H.,Tsinghua National Laboratory for Information Sciences and Technology | Yu H.,Tsinghua University | Chen M.,Tsinghua National Laboratory for Information Sciences and Technology | Chen M.,Tsinghua University | And 11 more authors.
Conference on Optical Fiber Communication, Technical Digest Series | Year: 2015

A full-band RF receiver ranging from L- to W-band based on the ultra-high Q bandpass filter has been proposed and experimentally demonstrated. The SFDR of the receiver from C- to K-band are larger than 114dB-Hz2/3. © 2015 OSA. Source


Yu H.,Tsinghua National Laboratory for Information Sciences and Technology | Yu H.,Tsinghua University | Chen M.,Tsinghua National Laboratory for Information Sciences and Technology | Chen M.,Tsinghua University | And 13 more authors.
IEEE Photonics Journal | Year: 2015

Digital signal processing has achieved great success in the field of signal processing over the past several decades. However, as the bandwidth requirement increases, the power consumption and effective number of bits (ENOB) of the analog-to-digital convertor (ADC) have become bottlenecks. One solution is returning to analog and applying microwave photonic technologies, which shows potential for multiband signal processing. In this paper, a programmable integrated analog photonic signal processor based on cascaded Mach-Zehnder interferometers (MZIs) and a channelized filter has been proposed. Different shapes of the signal processor can be acquired for different applications. The highest processing resolution is 143 MHz, and the processing range of the signal processor can be higher than 112.5 GHz. An application of the signal processor for the signal extraction in a radio frequency (RF) photonic frontend operating from L-band to K-band is presented. © 2009-2012 IEEE. Source


Yu H.,Tsinghua National Laboratory for Information Sciences and Technology | Chen M.,Tsinghua National Laboratory for Information Sciences and Technology | Guo Q.,Tsinghua National Laboratory for Information Sciences and Technology | Hoekman M.,LioniX | And 6 more authors.
Journal of Lightwave Technology | Year: 2016

Ultra-broadband radiofrequency (RF) receivers are required in higher frequency-band wireless communications, radar communications or multi-band applications in radio telescopes. Such ultra-broadband receivers are inherently difficult to establish with electronics because of limits in the bandwidth of the devices. Photonic means of RF photonic receivers/frontends can overcome the bandwidth limitation in electrical receivers. One aspect that should be considered is the precise signal processing in the optical domain. Here, a full-band (from the L-band to the W-band) all-optical RF receiver based on the Si3N4 microring filter is proposed and experimentally demonstrated. The resolution and processing range of the filter are lower than 420 MHz and larger than 112.9 GHz (FSR larger than 225.78 GHz), respectively, and the out-band suppression of this filter is greater than 40 dB. The center frequency of the filter can be altered for more than one FSR by tuning the phase-shifter on top of the ring. The performance of the full-band all-optical RF-receiver has been discussed, and the spurious free dynamic range of the receiver from the L-band to the Ka-band (limited by the bandwidth of the modulator in our experiment) has been measured to be larger than 111.6 dB·Hz2/3. © 1983-2012 IEEE. Source

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