De Araujo Filho G.M.,Federal University of Sao Paulo |
De Araujo Filho G.M.,Linc Inc |
Yacubian E.M.T.,Federal University of Sao Paulo
Epilepsy and Behavior | Year: 2013
Juvenile myoclonic epilepsy (JME) is a well-defined age-related idiopathic epilepsy syndrome. Past studies have emphasized the difficulties in the treatment of patients with JME, which have been attributed to some specific psychiatric, psychological, and psychosocial characteristics. These aspects have aroused a significant amount of interest in the last two decades. In this article, the available studies that investigated the prevalence of psychiatric disorders (PDs) in JME and its impact on seizure outcome were reviewed in order to provide an update to clinicians about these two important aspects associated with this common epilepsy syndrome. The review disclosed a high prevalence of PDs in patients with JME, particularly mood, anxiety, and personality disorders. In addition, most recent studies have also observed that overall prevalence of PDs in JME has not shown statistically significant differences when compared with TLE, an epilepsy syndrome where the psychiatric aspects are most frequently studied. Taken together, data regarding the prevalence of PDs and their possible consequences on seizure outcome on JME indicate that special attention should be directed to psychological disturbances and psychiatric symptoms in this epilepsy syndrome. The early recognition and treatment of psychiatric symptoms, as well as psychological disturbances and psychosocial difficulties, should be considered fundamental to JME prognosis. © 2013 Elsevier Inc.
Greenfield V.A.,RAND Corporation |
Paoli L.,Linc Inc
British Journal of Criminology | Year: 2013
Despite the centrality of harm to crime and criminalization and increasing interest in harm as a basis for crime-control policy, the criminological community has yet done little to systematically reflect on criminal harms or their identification, evaluation and comparison. This paper presents a newly developed framework with which to systematize the empirical assessment of such harms and address at least some of the attendant conceptual and technical challenges. It also suggests several roles for the framework in policy making. Our conclusions are twofold: it is possible to reliably evaluate the harms of criminal activities, as our examples suggest, but it is not possible - for both conceptual and technical reasons - to develop an encompassing estimate of the total harms of these activities. © The Author 2013.
Linc Inc | Date: 2012-02-20
Linc Inc | Date: 2012-09-28
The invention relates to compositions and method for construction of an underground coal gasification (UCG) well liner assembly. In particular, a well liner segment for use in the construction of a UCG well liner assembly for conveying product gas to a production well is disclosed. Also disclosed are a system and method for UCG product gas production.
Greenfield V.A.,U.S. Naval Academy |
Paoli L.,Linc Inc
International Journal of Drug Policy | Year: 2012
Critics of the international drug-control regime contend that supply-oriented policy interventions are not just ineffective, but, in focusing almost exclusively on supply reduction, they also produce unintended adverse consequences. Evidence from the world heroin market supports their claims. The balance of the effects of policy is yet unknown, but the prospect of adverse consequences underlies a central paradox of contemporary supply-oriented policy. In this paper, we evaluate whether harm reduction, a subject of intense debate in the demand-oriented drug-policy community, can provide a unifying foundation for supply-oriented drug policy and speak more directly to policy goals. Our analysis rests on an extensive review of the literature on harm reduction and draws insight from other policy communities' disciplines and methods. First, we explore the paradoxes of supply-oriented policy that initially motivated our interest in harm reduction; second, we consider the conceptual and technical challenges that have contributed to the debate on harm reduction and assess their relevance to a supply-oriented application; third, we examine responses to those challenges, i.e., various tools (taxonomies, models, and measurement strategies), that can be used to identify, categorize, and assess harms. Despite substantial conceptual and technical challenges, we find that harm reduction can provide a basis for assessing the net consequences of supply-oriented drug policy, choosing more rigorously amongst policy options, and identifying new options. In addition, we outline a practical path forward for assessing harms and policy options. On the basis of our analysis, we suggest pursuing a harm-based approach and making a clearer distinction between supply-oriented and supply-reduction policy. © 2011 .