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East Gaffney, SC, United States

Limestone College is a private four-year, coeducational liberal arts college located in Gaffney, South Carolina. Limestone College is a Christian non-denominational college with programs leading to the Bachelor of Arts, Bachelor of Science, Bachelor of Social Work, Associate of Arts, Associate of Science, and Masters in Business Administration degrees.Limestone was established in 1845 by Dr. Thomas Curtis and his son, Dr. William Curtis, distinguished scholars born and educated in England. Limestone was the first women's college in South Carolina, and one of the first in the nation. Ten buildings on the campus, as well as the Limestone Springs and limestone quarry itself, are on the National Register of Historic Places. In the 1960s, Limestone became fully coeducational, and today student enrollment is about 55:45 male:female. It is the third-oldest college in South Carolina.The college has expanded with branch campuses in Yemassee, Greer, Charleston, Kingstree, Graniteville, Florence, and Columbia that offer evening classes. Wikipedia.

Drachova S.V.,Limestone College | Hallstrom J.O.,Clemson University | Hallstrom J.O.,Institute for Sensing and Embedded Network Systems | Hollingsworth J.E.,Indiana University Southeast | And 3 more authors.
ACM Transactions on Computinig Education | Year: 2015

Undergraduate computer science students need to learn analytical reasoning skills to develop high-quality software and to understand why the software they develop works as specified. To accomplish this central educational objective, this article describes a systematic process of introducing reasoning skills into the curriculum and assessing how well students have learned those skills. To facilitate assessment, a comprehensive inventory of principles for reasoning about correctness that captures the finer details of basic skills that students need to learn has been defined and used. The principles can be taught at various levels of depth across the curriculum in a variety of courses. The use of a particular instructional process is illustrated to inculcate reasoning principles across several iterations of a sophomore-level development foundations course and a junior-level software engineering course. The article summarizes how learning outcomes motivated by the inventory of reasoning principles lead to questions that in turn form the basis for a careful analysis of student understanding and for finetuning teaching interventions that together facilitate continuous improvements to instruction. © 2015 ACM. Source

McGovern T.M.,Clemson University | McGovern T.M.,Limestone College | Keever C.C.,Simon Fraser University | Saski C.A.,Clemson University | And 2 more authors.
Molecular Ecology | Year: 2010

Coalescent samplers are computational time machines for inferring the historical demographic genetic processes that have given rise to observable patterns of spatial genetic variation among contemporary populations. We have used traditional characterizations of population structure and coalescent-based inferences about demographic processes to reconstruct the population histories of two co-distributed marine species, the frilled dog whelk, Nucella lamellosa, and the bat star, Patiria miniata. Analyses of population structure were consistent with previous work in both species except that additional samples of N.lamellosa showed a larger regional genetic break on Vancouver Island (VI) rather than between the southern Alexander Archipelago as in P.miniata. Our understanding of the causes, rather than just the patterns, of spatial genetic variation was dramatically improved by coalescent analyses that emphasized variation in population divergence times. Overall, gene flow was greater in bat stars (planktonic development) than snails (benthic development) but spatially homogeneous within species. In both species, these large phylogeographic breaks corresponded to relatively ancient divergence times between populations rather than regionally restricted gene flow. Although only N.lamellosa shows a large break on VI, population separation times on VI are congruent between species, suggesting a similar response to late Pleistocene ice sheet expansion. The absence of a phylogeographic break in P.miniata on VI can be attributed to greater gene flow and larger effective population size in this species. Such insights put the relative significance of gene flow into a more comprehensive historical biogeographic context and have important implications for conservation and landscape genetic studies that emphasize the role of contemporary gene flow and connectivity in shaping patterns of population differentiation. © 2010 Blackwell Publishing Ltd. Source

Fillmore P.T.,University of South Carolina | Phillips-Meek M.C.,University of South Carolina | Phillips-Meek M.C.,Limestone College | Richards J.E.,University of South Carolina
Frontiers in Aging Neuroscience | Year: 2015

This study created and tested a database of adult, age-specific MRI brain and head templates. The participants included healthy adults from 20 through 89 years of age. The templates were done in 5-year, 10-year, and multi-year intervals from 20 through 89 years, and consist of average T1W for the head and brain, and segmenting priors for GM, WM, and CSF. It was found that age-appropriate templates provided less biased tissue classification estimates than ageinappropriate reference data and reference data based on young adult templates. This database is available for use by other investigators and clinicians for their MRI studies, as well as other types of neuroimaging and electrophysiological research. © 2015 Fillmore, Phillips-meek and Richards. Source

Ismail L.,Limestone College
Reference and User Services Quarterly | Year: 2013

This study surveyed adult learners in a graduate social work program to determine their library help-seeking preferences and reasons behind their reluctance to seek help from a librarian. It also investigates the preferred method of seeking library help (online, face-to-face, etc) and whether age and location (students enrolled in the off campus/distance programs) had an impact on these preferences. Findings indicate that librarians are approached last for research help (the first being either their friends/classmates or instructors), that age does have some impact on library helpseeking, and that distance adult learners still preferred to seek librarian help face-to face if this option was available. © 2013 American Library Association. All rights reserved. Source

Culbreath C.,University of Alabama at Birmingham | Tanner S.M.,Limestone College | Yeramilli V.A.,University of Alabama at Birmingham | Berryhill T.F.,University of Alabama at Birmingham | And 2 more authors.
Journal of Surgical Research | Year: 2015

Background Immunoglobulin A (IgA) plays a key role in coating luminal antigens and preventing translocation of harmful bacteria. The aryl hydrocarbon receptor (AhR) is a basic helix-loop-helix transcription factor that when stimulated activates factors important for barrier function and intestinal homeostasis. We hypothesize that AhR signaling is critical for establishment of intestinal homeostasis in neonates. Material and methods Mice: C57BL/6 (B6) AhR+/+ wild type (WT), B6.AhR-/- Aryl-hydrocarbon receptor knockout (KO), and B6.AhR+/+ raised on an AhR ligand-free diet (AhR LF). Enzyme-linked immunosorbent assay was used to measure fecal and serum IgA levels. Bacterial translocation was measured by culturing the mesenteric lymph nodes. Results Two week old KO mice had significantly less fecal IgA compared with WT (and AhR LF, P value = 0.0393. The amount of IgA from the gastric contents of 2-wk-old mice was not significantly different. At age 8 wk, AhR LF mice had significantly less fecal IgA than WT and KO P value = 0.0077. At 2 wk, KO mice had significantly higher levels of bacterial translocation and at 8 wk AhR LF had significantly higher levels of bacterial translocation compared with WT. Conclusions In neonatal mice, the lack of AhR signaling is associated with loss of intestinal homeostasis, evidenced by decreased levels of IgA and increased bacterial translocation. In adult mice, exogenous AhR ligand and not receptor signaling is necessary for maintenance of intestinal integrity. © 2015 Elsevier Inc. Source

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