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Joosten E.,University Hospitals | Demuynck M.,University Hospitals | Detroyer E.,Catholic University of Leuven | Detroyer E.,Limburg Catholic University College | And 2 more authors.
BMC Geriatrics | Year: 2014

Background: The prevalence and significance of frailty are seldom studied in hospitalized patients. Aim of this study is to evaluate the prevalence of frailty and to determine the extent that frailty predicts delirium, falls and mortality in hospitalized older patients. Methods. In a prospective study of 220 older patients, frailty was determined using the Cardiovascular Health Study (CHS) and the Study of Osteoporotic Fracture (SOF) frailty index. Patients were classified as nonfrail, prefrail, and frail, according to the specific criteria. Covariates included clinical and laboratory parameters. Outcome variables included in hospital delirium and falls, and 6-month mortality. Results: The CHS frailty index was available in all 220 patients, of which 1.5% were classified as being nonfrail, 58.5% as prefrail, and 40% as frail. The SOF frailty index was available in 204 patients, of which 16% were classified as being nonfrail, 51.5% as prefrail, and 32.5% as frail. Frailty, as identified by the CHS and SOF indexes, was a significant risk factor for 6-month mortality. However, after adjustment for multiple risk factors, frailty remained a strong independent risk factor only for the model with the CHS index (OR 4.7, 95% CI 1.7-12.8). Frailty (identified by CHS and SOF indexes) was not found to be a risk factor for delirium or falls. Conclusions: Frailty, as measured by the CHS index, is an independent risk factor for 6-month mortality. The CHS and the SOF indexes have limited value as risk assessment tools for specific geriatric syndromes (e.g., falls and delirium) in hospitalized older patients. © 2014Joosten et al.; licensee BioMed Central Ltd. Source


Eyckens P.,Catholic University of Leuven | Van Bael A.,Catholic University of Leuven | Van Bael A.,Limburg Catholic University College | Van Houtte P.,Catholic University of Leuven
International Journal of Plasticity | Year: 2011

Some metal sheet forming processes may induce an amount of plastic shear over the sheet thickness. This paper investigates how formability of anisotropic sheet metal is affected by such through-thickness shear (TTS). The Marciniak-Kuczynski (MK) model framework, a commonly used analytical tool to predict the limit of sheet formability due to the onset of localized necking, is extended in this paper in order to explicitly account for TTS in anisotropic metal sheets. It is a continuation of previous work by the present authors (Eyckens et al., 2009), in which TTS is incorporated for isotropic sheet. This is achieved by the introduction of additional force equilibrium and geometric compatibility equations that govern the connection between matrix and groove in the MK model. Furthermore, in order to integrate plastic anisotropy, a material reference frame available in recent literature is incorporated, as well as a particular model for anisotropic yielding that relies on virtual testing of anisotropic properties (Facet plastic potential), since out-of-plane anisotropy related to TTS cannot be measured experimentally. It is found that formability may be increased by TTS, depending on the direction onto which it is imposed by the forming process. TTS is thus a relevant aspect of the formability in, for instance, sheet forming processes in which sliding contact with friction between sheets and forming tools occur. © 2011 Elsevier Ltd. All rights reserved. Source


Bogaerts A.F.L.,Limburg Catholic University College | Van Den Bergh B.R.H.,University of Tilburg | Van Den Bergh B.R.H.,Catholic University of Leuven | Witters I.,University Hospitals Leuven | Devlieger R.,University Hospitals Leuven
Obesity | Year: 2013

Objective We aimed to describe the weight status of obese mothers 6 months after delivery and examine its relationship to important sociodemographical, behavioral, and psychological variables. Design and Methods Postpartum data from an interventional trial in obese pregnant women (n = 197), conducted in three regional hospitals, between March 2008 and June 2012, were available from 150 mothers. Obesity was defined as body mass index (BMI) ≥ 29 kg/m2. Predictors were examined from the pregnancy and postpartum period. Descriptive statistics were performed and linear regression models constructed. Results Postpartum weight retention (PPWR) 6 months after delivery ranges from -17 to + 19 kg with a mean of -1.28 kg (SD 6.05). Thirty-nine percent showed PPWR (>0 kg) and 13% of obese mothers reported a high PPWR (≥5 kg). Gestational weight gain (GWG) and psychological discomfort were significantly higher in obese mothers with PPWR compared to those with no or low PPWR. Mean duration of breastfeeding in this cohort of obese mothers was 9.5 weeks (SD 8.7), with 17.3% breastfeeding for at least 6 months. At 6 months after delivery, prepregnancy BMI (β = -0.283; P = 0.001), GWG (β = 0.337; P = 0.001), and maternal trait anxiety in the first trimester of pregnancy (β = 0.255; P = 0.001) were significantly associated with PPWR in obese mothers. Conclusion PPWR in obese mothers is associated with psychological discomfort during early pregnancy. Besides the importance of adequate prenatal weight management, focused psychological support should be an important cue to action in obese women, to prevent maternal obesity on the long run. Copyright © 2013 The Obesity Society. Source


Grant
Agency: Cordis | Branch: FP7 | Program: MC-ITN | Phase: FP7-PEOPLE-2013-ITN | Award Amount: 1.69M | Year: 2013

TRADERS focuses on developing and testing a framework of methodologies on which art and design (A&D) researchers can rely when working on public space projects in participatory ways. This framework is transferable and aims to enhance the potentials in A&D practices to contribute creatively in processes of urban and branch-related change. The framework will inform and will be informed by a toolkit. For coherence in the training, Hasselt-Genk will be the anchor case area on which the ESR researchers work together. TRADERS will cooperate with Z-OUT: a centre of expertise on art, design and architecture in relation to public space. To assure the adequacy of an A&D research project, five complementary research foci are covered that correspond to the methodological framework and entail innovative research topics on participation for public space: Intervention (KHLIM (research group Social Spaces, Media, Arts & Design Faculty i.c.w. LUCA)), Play (UGOT), Multiple Performative Mapping (DAE), Data-mining (RCA) and Modeling in dialogue (CHALMERS). A sixth focus will be on the development of a meta-framework allowing these research foci to communicate and collaborate (KU Leuven). To bundle the strengths of different disciplines to commonly approach other non-A&D disciplines and sectors, every participant will work in a partnership with a public or private organization, offering a research and training environment to the researcher and ensuring that his/her research project has a practical and use-oriented focus. TRADERS contains a training program consisting of, a.o.: supervised involvement in six research/training projects at the host organizations with shared activities in Training-through-Research Synergy weeks, collaboration for the research/training with stakeholders and branches that represent future employers, collaboration with various researchers and enterprises from different countries, network-wide research training and Complementary Skills Training at Summer Schools, conference and secondments to associated partners.


Grant
Agency: Cordis | Branch: FP7 | Program: CSA-SA | Phase: SiS.2013.2.2.1-1 | Award Amount: 2.79M | Year: 2014

The Ark of Inquiry project aims to raise youth awareness to Responsible Research and Innovation (RRI) by providing young European citizens (7 to 18-year-olds) with a pool of engaging inquiry activities to improve their inquiry skills, increase their awareness and understanding of conducting real science, and prepare them to participate in different roles in the European research and innovation process. In order to achieve these aims, the project will 1) develop a framework for identifying inquiry activities that promote pupils awareness of RRI; 2) collect existing inquiry activities and environments from various national and international projects; 3) make the activities available across Europe through the Ark of Inquiry platform in order to bring together inquiry activities, learners, and supporters (teachers, science and teacher education students, and staff of universities and science centres); 4) train at least 1 100 teachers to support pupils inquiry activities in a manner that attracts pupils interest and motivation towards RRI; and 5) implement the inquiry activities on a large-scale across a European school network. During the project at least 23 000 students will participate in the Ark of Inquiry. After completing a particular set of inquiry activities the pupils can apply for an Inquiry Award. A large community consisting of 1 100 trained teachers and at least 100 science and teacher education students and 50 researchers from universities and science centres over Europe will support learners inquiry activities and award their performance. Based on evaluation results the Ark of Inquiry platform will be made available for the whole of Europe. The platform will connect formal learning settings and curricula to centres for science and research, so that generations of scientists can meet each other. This project helps build a society skilled in RRI and related scientific communication.

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