Kalach N.,Lille Catholic University
Hepato-Gastro and Oncologie Digestive | Year: 2017
In Western countries, constipation achieve nearly one third of the children and is in constant increase. In the majority of cases, the constipation is functional and the management is simple followed by a favourable evolution. Nevertheless, the general practitioner or the paediatrician must know to detect constipation of organic origin or complicated cases that require more specialized catch of load. Functional constipation diagnosis is mainly based on clinical history and medical exam of the child. The performances of complementary work-up and radiological and/or mano-metric procedures are discussed case by case. © 2017 John Libbey Eurotext.
De Bock K.W.,Ghent University |
De Bock K.W.,Lille Catholic University |
Poel D.V.D.,Ghent University
Expert Systems with Applications | Year: 2011
Several studies have demonstrated the superior performance of ensemble classification algorithms, whereby multiple member classifiers are combined into one aggregated and powerful classification model, over single models. In this paper, two rotation-based ensemble classifiers are proposed as modeling techniques for customer churn prediction. In Rotation Forests, feature extraction is applied to feature subsets in order to rotate the input data for training base classifiers, while RotBoost combines Rotation Forest with AdaBoost. In an experimental validation based on data sets from four real-life customer churn prediction projects, Rotation Forest and RotBoost are compared to a set of well-known benchmark classifiers. Moreover, variations of Rotation Forest and RotBoost are compared, implementing three alternative feature extraction algorithms: principal component analysis (PCA), independent component analysis (ICA) and sparse random projections (SRP). The performance of rotation-based ensemble classifier is found to depend upon: (i) the performance criterion used to measure classification performance, and (ii) the implemented feature extraction algorithm. In terms of accuracy, RotBoost outperforms Rotation Forest, but none of the considered variations offers a clear advantage over the benchmark algorithms. However, in terms of AUC and top-decile lift, results clearly demonstrate the competitive performance of Rotation Forests compared to the benchmark algorithms. Moreover, ICA-based Rotation Forests outperform all other considered classifiers and are therefore recommended as a well-suited alternative classification technique for the prediction of customer churn that allows for improved marketing decision making. © 2010 Elsevier Ltd. All rights reserved.
Conroy T.,University of Lorraine |
Conroy T.,Center Alexis Vautrin |
Gavoille C.,University of Lorraine |
Adenis A.,Lille Catholic University
Current Opinion in Oncology | Year: 2011
Purpose of Review: Metastatic pancreatic ductal adenocarcinoma has a grim prognosis and gemcitabine has been the reference treatment for 15 years. In this article, we will review current first-line treatments for metastatic pancreatic adenocarcinoma focusing on randomized studies. Recent Findings: Among the numerous randomized phase III studies comparing gemcitabine as single agent to gemcitabine combined to a new agent, only the gemcitabine-erlotinib combination has shown a small, but statistical improvement in survival. A trend to better survival was also observed with a gemcitabine-capecitabine regimen. The use of low-weight heparin may be of value to reduce venous thromboembolic events. In selected patients with good performance status ECOG 0-1, the Folfirinox regimen, when compared with gemcitabine, was associated with more toxicities and significantly increased median survival from 6.8 to 11.1 months. Summary: Gemcitabine (with or without erlotinib or capecitabine) is still the reference treatment in patients with ECOG performance status 2. Folfirinox is a new more toxic and more efficient regimen that may be considered in patients with good performance status. © 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins.
Zhang L.L.,Lille Catholic University |
Jiao R.J.,Georgia Institute of Technology
Decision Support Systems | Year: 2013
Facilitating production process planning for product families, process platform planning (P3) has been well recognized as an effective means of achieving production efficiency. To support decision making in P3 automation, this study adopts graph rewriting systems to 1) organize large volumes of product and process data and 2) model production process planning reasoning. The model developed represents the structural and behavioral aspects of process platforms as family graphs and related graph transformations, respectively. In view of its modeling advantage, the system is formally defined using PROGRES. It includes meta, generic, and instance models at three different levels of abstraction. Meta models are defined for family graphs to generalize the patterns common to planning production processes for different product families; generic models are defined to describe entities pertaining to production processes of specific product families; instance models represent production processes producing product variants in a family. The graph rewriting system-based P3 model is applied to textile spindles' production process planning. The results obtained have demonstrated its potential and feasibility to support decision making in P3 automation. © 2012 Elsevier B.V.
Ritvala T.,Aalto University |
Kleymann B.,Lille Catholic University
Industry and Innovation | Year: 2012
The question of how embedded actors can create institutions that support cluster emergence remains unsolved in the cluster and national innovation systems literature. The present paper extends the recent literature on institutional entrepreneurship and institutional work to solve this paradox of embedded agency in the context of science-based clusters. Building on a longitudinal single case study of a functional foods cluster in Finland, we present an institutional work framework for cluster formation. We argue that, in addition to ideational, material and bridging work, authentic leadership work is critical for cluster emergence. The results of the study highlight the opportunities that scientists have to act as midwives to cluster formation, but they also show that well-functioning clusters need a broader support base. © 2012 Copyright Taylor and Francis Group, LLC.
Zhang L.L.,Lille Catholic University |
Vareilles E.,Toulouse University Mines Albi |
Aldanondo M.,Toulouse University Mines Albi
International Journal of Production Research | Year: 2013
Most available studies on configuration focus on either sales configuration specifying functional features or production configuration addressing product components. It has been well recognised that automating most of the activities associated with specification, engineering, and process planning of customised products and their interactions is one key in achieving product customisation. Thus, treating sales configuration and product configuration separately may not contribute to product customisation from a systematic view although they may lead to the improvement of individual stages. Recognising this limitation of existing studies, in this paper, we propose integrated SAles, Product and Production (SAP2) configuration, which helps achieve product customisation from a holistic view. Its rationale lies in automating consistently sales, product and production configuration activities in one system. In view of the importance of configuration models, we focus on the model underpinning SAP2 configuration called generic bill of functions, materials and operations (GBoFMO) and discuss it in detail. As the core of SAP2 configuration, GBoFMO can provide companies with an insight into organising the large volumes of data and knowledge in the life cycle of product family development. We also report a case study of light passenger aircrafts to illustrate the GBoFMO. © 2013 Taylor & Francis.
Didier C.,Lille Catholic University |
Derouet A.,Ecole de Hautes Etudes en science Sociales
Science and Engineering Ethics | Year: 2013
In France, some institutions seem to call for the engineer's sense of social responsibility. However, this call is scarcely heard. Still, engineering students have been given the opportunity to gain a general education through courses in literature, law, economics, since the nineteenth century. But, such courses have long been offered only in the top ranked engineering schools. In this paper, we intend to show that the wish to increase engineering students' social responsibility is an old concern. We also aim at highlighting some macro social factors which shaped the answer to the call for social responsibility in the French engineering "Grandes Ecoles". In the first part, we provide an overview of the scarce attention given to the engineering curriculum in the scholarly literature in France. In the second part, we analyse one century of discourses about the definition of the "complete engineer" and the consequent role of non technical education. In the third part, we focus on the characteristics of the corpus which has been institutionalized. Our main finding is that despite the many changes which occurred in engineering education during one century, the "other formation" remains grounded on a non academic "way of knowing", and aims at increasing the reputation of the schools, more than enhancing engineering students' social awareness. © 2011 Springer Science+Business Media B.V.
Zhang L.L.,Lille Catholic University
International Journal of Production Economics | Year: 2015
With intense global competition, many manufacturing companies pursue a platform strategy to develop diverse products belonging to a family, while utilizing available manufacturing resources. In the past, enormous efforts have been made in investigating product platforms, which exploit platforming potential at the design stage. Researchers have recently discussed new platform concepts, which capitalize on platforming potential at different product family development stages, in addition to investigating more issues pertaining to product platforms. These efforts contribute to the continuous progress on platforming research. This study provides a review of progress on platforming. It identifies and reviews the available platform concepts, including flexible platforms, function-technology platforms, process platforms, and process parameter platforms. It also highlights several trends in platforming research, thus providing an overall picture of platform based-product family development requirements and the corresponding solutions. Based on the review, a framework is presented for future research. © 2015 Elsevier B.V. All rights reserved.
Charry K.M.,Lille Catholic University |
Demoulin N.T.M.,Lille Catholic University
International Journal of Advertising | Year: 2012
Threat appeals are effective in persuading tweens to concretely select die healthy food options. Managers and people in charge of public health should seriously consider this option, as it is more effective than traditional appeals (action, adventure, info, etc.) and consequendy improves the ROI. Low levels of negative affective reactions are sufficient for the appeal to be effective (max. 1.5 out of 4). It is not necessary to elicit strong responses to create successful ads. Beyond fear that may cause anxiety, negative affective reactions such as disgust and sadness should be considered when creating the scenarios. They appear to trigger the expected behaviours while avoiding stressful situations. The authors nevertheless recommend not using threat appeals in traditional marketing contexts as it may appear unethical to threaten children for turnover objectives and consequendy impair the company's image. © 2012 Advertising Association.
Zhang L.L.,Lille Catholic University
International Journal of Production Research | Year: 2014
Being able to provide companies with a number of advantages in delivering customised products, product configuration has received increasing attention from the academia and lasting interests from industries in the past several decades. While several surveys and reviews have been reported shedding light on specific issues in product configuration, a general overview is missing. By systematically presenting important concepts, definitions and issues underlying product configuration, such a review is of paramount importance to develop practical solutions, which ultimately contributes to efficient design, development and implementation of product configurators in practice. This study, thus, tries to fill this gap by reviewing the state-of-the-art research on product configuration. It touches on the major issues, definitions and concepts in product configuration along with the corresponding studies, such as configuration ontology, system design and development, and configuration solving. Based on the review, future research is highlighted as well. © 2014 Taylor and Francis.