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Eugene, OR, United States

Life Technologies is a global biotechnology company headquartered in Carlsbad, California. It possesses a portfolio of more than 9 million genetic research assays and custom solutions. As of 2011, the company had sales of $3.7 billion, employed a workforce of approximately 11,000, maintained a portfolio of more than 4,000 patents and exclusive licenses, and markets over 50,000 products. Wikipedia.


Patent
Life Technologies | Date: 2015-03-17

A fluid mixing system includes a flexible bag having an interior surface bounding a compartment. An elongated first tubular connector is disposed within the compartment of the flexible bag, the first tubular connector having a first end and an opposing second end, the first end of the first tubular connector being coupled with the flexible bag. An elongated second tubular connector is disposed within the compartment of the flexible bag, the second tubular connector being more rigid than the first tubular connector and having a first end coupled to the second end of the first tubular connector. A plurality of impeller are disposed on the elongated second tubular connector at spaced apart locations.


A method is provided in various embodiments for determining a profile data set for a subject with infectious disease or inflammatory conditions related to infectious disease based on a sample from the subject, wherein the sample provides a source of RNAs. The method includes using amplification for measuring the amount of RNA corresponding to at least 2 constituents from Table 1. The profile data set comprises the measure of each constituent, and amplification is performed under measurement conditions that are substantially repeatable.


Patent
Life Technologies | Date: 2015-10-09

In some embodiments, the present inventions relates generally to compositions, methods and kits for use in discriminating sequence variation between different alleles. More specifically, in some embodiments, the present invention provides for compositions, methods and kits for quantitating rare (e.g., mutant) allelic variants, such as SNPs, or nucleotide (NT) insertions or deletions, in samples comprising abundant (e.g., wild type) allelic variants with high specificity and selectivity. In particular, in some embodiments, the invention relates to a highly selective method for mutation detection referred to as competitive allele-specific TaqMan PCR (cast-PCR).


Patent
Life Technologies | Date: 2015-07-15

The present invention provides lipid aggregate compositions having at least two cationic lipids in combination with one or optionally more than one non-cationic lipids for the in vitro and/or in vivo delivery of biologically active molecules including nucleic acids, specifically DNA and RNA, and proteins into cells and tissues. Methods are also provided that use the compounds of the present invention to deliver biologically active molecules, into cells and tissues to facilitate the expression of target proteins therein. In some non-limiting embodiments, the subject lipid aggregate compositions can be used to deliver nucleic acid molecules to facilitate the expression of proteins involved in cellular reprogramming and genome editing applications.


Patent
Life Technologies | Date: 2015-07-09

The present invention provides methods, compositions, kits, systems and apparatus that are useful for determining copy number variation of one or more nucleic acids present in a sample. In some aspects, the method includes various target-specific primers that allow for the selective amplification of one or more target nucleic acids in the sample. In yet another aspect, the invention relates to determining copy number variation with respect to gene or chromosome representation of a nucleic acid in the sample. In some aspects, the method for determining copy number variation of different target nucleic acids in a sample using the disclosed methods, kits, systems and apparatuses can be used in various downstream processes including diagnosis, predictive therapeutic regimes or other therapeutic purposes.

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