Liu D.,Liaohe Oilfield General Hospital |
Liang Y.-H.,Liaohe Oilfield General Hospital |
Dong M.,Liaohe Oilfield General Hospital |
Jiang Y.-H.,Liaohe Oilfield General Hospital
Chinese Journal of Tissue Engineering Research | Year: 2015
BACKGROUND: Foot soft tissue defect can be repaired by skin flap transplantation technology. Vacuum sealing drainage technology can support a good tissue bed for skin flap transplantation, thereby to speed up the local growth of granulation tissue. OBJECTIVE: To further verify the application value of vacuum sealing drainage combined with flap transplantation in foot soft tissue repair. METHODS: A retrospective analysis was performed on the clinical data of 23 cases of foot soft tissue defects, and these 23 cases were divided into observation group (vacuum sealing drainage combined with flap transplantation; n=12) and control group (flap transplantation with no vacuum sealing drainage; n=11) according to the repair scheme. RESULTS AND CONCLUSION: The overall therapeutic excellent rate and survival rate of the flap in the observation group were significantly higher than those in the control group (both P < 0.05). All the 23 patients were followed up for 6 months, and the follow-up rate was 100%. In the observation group, the flaps survived well with red and yellow color, which were soft and had no distinct difference from the surrounding normal skin tissues. The therapeutic effect in the observation group was better than that in the control group. These findings indicate that vacuum sealing drainage combined with flap transplantation in foot soft tissue repair can achieve better effects in the repair of foot soft tissue defects and has certain value in clinical application. © 2015, Journal of Clinical Rehabilitative Tissue Engineering Research. All rights reserved.
Liu C.-F.,Liaohe Oilfield General Hospital |
Wang F.-Y.,Liaohe Oilfield General Hospital
Chinese Journal of Contemporary Neurology and Neurosurgery | Year: 2013
The curative effect of cinepazide maleate (320 mg/d) and nimodipine (30 mg/d) on the cerebral vasospasm caused by post-traumatic subarachnoid hemorrhage was compared. Transcranial Doppler ultrasound (TCD) was used to examine the changes of hemodynamics of middle cerebral artery (MCA) before and after treatment. On the 3rd day after treatment the blood flow velocity of MCA in both groups decreased obviously, and the difference between that in pre-and post-treatment was statistically significant (cinepazide maleate group t = 4.364, P = 0.000; nimodipine group t = 7.486, P = 0.000), but there was no statistically significant difference between 2 groups (P = 0.124). On the 7th day, the blood flow velocity of 2 groups continously declined (cinepazide maleate group t = 5.793, P = 0.000; nimodipine group t = 10.364, P = 0.000), but there was no significant difference between 2 groups (P = 0.364). No statistically significant difference on total effective rate and adverse drug reaction rate was seen between 2 groups (P > 0.05). It was suggested that cinepazide maleate can replace nimodipine in the treatment for cerebral vasospasm after subarachnoid hemorrhage.