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Lee S.-Y.,LGE Advanced Research Institute | Ahn S.-w.,LGE Advanced Research Institute | Lee H.-M.,LGE Advanced Research Institute
Current Applied Physics | Year: 2010

Surface morphology and crystallinity of silicon p-layer have been investigated on the effect of various deposition conditions of RFPECVD in order to clarify crystalline nuclei evolution. Crystallinity increased with increasing hydrogen dilution, but decreased with increasing both RF input power and diborane doping. Microcrystalline nuclei size increased with increasing working pressure, RF input power and substrate temperature. However, surface morphology was not correlated with crystallinity or deposition rate. A film with relatively large nuclei but having rather low crystallinity can be prepared for some condition, and vice versa. In order to get a dense microcrystalline silicon intrinsic layer subsequently deposited, surface morphology control of microcrystalline p-layer seems to be important as well as crystallinity. © 2009 Elsevier B.V. All rights reserved.


Kim S.,Seoul National University | Kim C.-B.,Sangmyung University | Min G.-S.,Inha University | Suh Y.,Seoul National University | And 32 more authors.
Animal Cells and Systems | Year: 2012

A major concern regarding the collection and storage of biodiversity information is the inefficiency of conventional taxonomic approaches in dealing with a large number of species. This inefficiency has increased the demand for automated, rapid, and reliable molecular identification systems and large-scale biological databases. DNA-based taxonomic approaches are now arguably a necessity in biodiversity studies. In particular, DNA barcoding using short DNA sequences provides an effective molecular tool for species identification. We constructed a large-scale database system that holds a collection of 5531 barcode sequences from 2429 Korean species. The Korea Barcode of Life database (KBOL, http://koreabarcode.org) is a web-based database system that is used for compiling a high volume of DNA barcode data and identifying unknown biological specimens. With the KBOL system, users can not only link DNA barcodes and biological information but can also undertake conservation activities, including environmental management, monitoring, and detecting significant organisms. © 2012 Copyright Korean Society for Integrative Biology.


Lee S.-Y.,LGE Advanced Research Institute | Shim J.H.,LGE Advanced Research Institute | You D.J.,LGE Advanced Research Institute | Ahn S.-W.,LGE Advanced Research Institute | Lee H.-M.,LGE Advanced Research Institute
Solar Energy Materials and Solar Cells | Year: 2011

We present the novel use of spectroscopic ellipsometry (SE) for the development of a-Si:H solar cell. SE is a very fast and useful tool to measure various optical properties of thin film. In the case of a-Si:H thin film analysis, generally, SE is used to estimate the film thickness, roughness, void fraction, optical constants such as (n,k), and so forth. In this study, optical parameters from SE measurements were analyzed with relation to structural and electrical properties of a-Si:H thin film for solar cell. By analyzing IR absorption spectra and conductivity measurements, it was affirmed that <ε 2> and parameter A by TaucLorentz model fitting of SE data are representative parameters qualifying a-Si:H thin film, and that they have close relationships with FF and light induced degradation property of solar cells. Based on the analysis, solar cells that have i-layers with various E g were optimized. By this research, easier and faster methodology to develop a-Si:H thin film for thin film Si solar cells using SE measurements was established. © 2010 Elsevier B.V. All rights reserved.


Lee J.,Korea Polar Research Institute | Noh E.K.,Korea Polar Research Institute | Choi H.-S.,LGE Advanced Research Institute | Shin S.C.,Korea Polar Research Institute | And 2 more authors.
Planta | Year: 2013

Antarctic hairgrass (Deschampsia antarctica Desv.) is the only natural grass species in the maritime Antarctic. It has been studied as an extremophile that has successfully adapted to marginal land with the harshest environment for terrestrial plants. However, limited genetic research has focused on this species due to the lack of genomic resources. Here, we present the first de novo assembly of its transcriptome by massive parallel sequencing and its expression profile using D. antarctica grown under various stress conditions. Total sequence reads generated by pyrosequencing were assembled into 60,765 unigenes (28,177 contigs and 32,588 singletons). A total of 29,173 unique protein-coding genes were identified based on sequence similarities to known proteins. The combined results from all three stress conditions indicated differential expression of 3,110 genes. Quantitative reverse transcription polymerase chain reaction showed that several well-known stress-responsive genes encoding late embryogenesis abundant protein, dehydrin 1, and ice recrystallization inhibition protein were induced dramatically and that genes encoding U-box-domain-containing protein, electron transfer flavoprotein-ubiquinone, and F-box-containing protein were induced by abiotic stressors in a manner conserved with other plant species. We identified more than 2,000 simple sequence repeats that can be developed as functional molecular markers. This dataset is the most comprehensive transcriptome resource currently available for D. antarctica and is therefore expected to be an important foundation for future genetic studies of grasses and extremophiles. © 2012 Springer-Verlag Berlin Heidelberg.


PubMed | LGE Advanced Research Institute
Type: Journal Article | Journal: Molecules and cells | Year: 2012

Breast cancer is a clinically heterogeneous disease characterized by distinct molecular aberrations. Understanding the heterogeneity and identifying subgroups of breast cancer are essential to improving diagnoses and predicting therapeutic responses. In this paper, we propose a classification scheme for breast cancer which integrates data on differentially expressed genes (DEGs), copy number variations (CNVs) and microRNAs (miRNAs)-regulated mRNAs. Pathway information based on the estimation of molecular pathway activity is also applied as a postprocessor to optimize the classifier. A total of 250 malignant breast tumors were analyzed by k-means clustering based on the patterns of the expression profiles of 215 intrinsic genes, and the classification performances were compared with existing breast cancer classifiers including the BluePrint and the 625-gene classifier. We show that a classification scheme which incorporates pathway information with various genetic variations achieves better performance than classifiers based on the expression levels of individual genes, and propose that the identified signature serves as a basic tool for identifying rational therapeutic opportunities for breast cancer patients.

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