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The Woodlands, TX, United States

Patent
Lexicon Pharmaceuticals Inc. | Date: 2011-02-09

This invention relates to tryptophan hydroxylase inhibitors, compositions comprising them, and methods of their use for the treatment, management and/or prevention of metastatic bone disease.


Patent
Lexicon Pharmaceuticals Inc. | Date: 2013-06-10

Methods of improving the cardiovascular and/or metabolic health of patients, particularly those suffering from type 2 diabetes, are disclosed, as well as compounds and pharmaceutical compositions useful therein.


Patent
Lexicon Pharmaceuticals Inc. | Date: 2012-01-04

Methods of treating and managing ulcerative colitis, using imidazole-based compounds that inhibit S1P lyase, are disclosed.


Imidazo[1,2-b]pyridazine-based compounds of the formula: are disclosed, wherein R


Patent
Lexicon Pharmaceuticals Inc. | Date: 2013-11-18

Inhibitors of sodium glucose cotransporter 1 (SGLT1), compositions comprising them, and methods of their use to treat diseases and disorders such as diabetes are disclosed. Particular compounds are of the formula: the various substituents of which are defined herein.

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