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Leshan, China

Chang S.,South China Agricultural University | Hu J.-P.,Leshan Teachers College | Lin P.-Y.,South China Agricultural University | Jiao X.,Taiyuan University of Technology | Tian X.-H.,South China Agricultural University
Molecular BioSystems | Year: 2010

The l-arginine (Arg)/agmatine (Agm) antiporter AdiC is a vital transport protein of the arginine-dependent extreme acid resistance system of enteric bacteria. Recently, both substrate-free and Arg-bound structures of AdiC were determined by X-ray crystallography. In this article, the two different proteins were investigated with three simple models. Gaussian network model provided the information of conformational changes. It is found that Arg binding induces structural rearrangement in the extracellular domain, and transmembrane helix 6 (TM6) has the most pronounced trend of conformational changes. The moving directions of fluctuation regions were further ascertained by using anisotropy elastic network model and cross-correlation analysis. Interestingly, the two substrate-binding sites hypothesis of AdiC was confirmed directly by molecular docking. Furthermore, the binding preferences of these two sites were explained from the aspects of electrostatic complementarity and geometric matching. These simple coarse-grained analyses can be used as a general and quick method for the mechanism studies of transport proteins. © 2010 The Royal Society of Chemistry. Source


Hu L.,Leshan Teachers College
Proceedings of 2011 International Conference on Electronic and Mechanical Engineering and Information Technology, EMEIT 2011 | Year: 2011

The purpose of this paper is to propose a new algorithm which is based on combining the linear model and the method about smooth exponential. It is used to simulate the AR model of the Single sliding window sequence of observations and gets the average value of the square of slide window observed values' residual noise and achieve the previous statistics on the latter statistic forecast with exponential smoothing method so as to decide whether the network traffic is normal or not. This algorithm is more efficiently comparing with GLR method and more reliable comparing with smooth exponential method, and has been proved is effectively in the detection for network traffic anomalies. © 2011 IEEE. Source


Zhang J.,Leshan Teachers College
Communications in Computer and Information Science | Year: 2011

This paper explains a small power photovoltaic control system based on PLD. And a new way is applied to trace the maximum power point based on the improved accelerating simplex method. The system perfects the management and protection for the charge and discharge of storage battery also for the load and solar power supply. It's very important part that the techniques of maximum power point tracking and islanding protecting, but also the technique for inverter to connected with grid are discussed at emphasis. This system scheme can be made use of in several photovoltaic products and obtain the satisfied result. © 2011 Springer-Verlag Berlin Heidelberg. Source


Hu J.,Leshan Teachers College | Wang C.,Beijing University of Technology
Chinese Journal of Chemistry | Year: 2010

The biological function of HIV-1 integrase (IN) is to integrate viral DNA into the host cell chromosome, and the specific binding of IN with viral DNA is a precondition for IN to function correctly. Beforehand, the binding mode of IN dimer (IN 2) with the 27 bp segment of viral DNA before 3' processing (3'-P) was obtained via a molecular docking method. Based on the binding mode, the aim of this article was to explore the changes of motive mode and correlative motion for the IN 2 and DNA systems after their binding through dynamical cross-correlation map (DCCM) and principal component analysis (PCA). Finally, solvent effect during the association was analyzed briefly. The results show that there is a significantly increased positive correlation in the interface region between IN 2 and viral DNA, and some obvious motive mode changes of the two systems (IN 2 and DNA) were also observed after their binding. It was found that water molecules played an important role in the recognition between IN 2 and viral DNA through analyzing the water-mediated hydrogen bonds. © 2010 SIOC, CAS, Shanghai, & WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. Source


Li X.-M.,Leshan Teachers College
Defect and Diffusion Forum | Year: 2010

The local distortion of the impurity Ni+ center in magnesium oxide is theoretically studied by analyzing its electron paramagnetic resonance g factor from the formula of a 3d9 ion under octahedra with tetragonal elongation deformation. The defect center is suggested to exhibit the relative elongation along the four-fold axis by about 0.05 Ä of the Jahn-Teller nature. The observed isotropic g factor (≈ 2.2391) is attributable to the dynamical average of the anisotropic g values under tetragonal elongation due to the dynamical Jahn-Teller effect. © (2010) Trans Tech Publications. Source

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