Leeds General Infirmary Leeds

Welton, United Kingdom

Leeds General Infirmary Leeds

Welton, United Kingdom
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Guidoin R.,Laval University | Fu Y.,Donghua University | Li B.,Laval University | Li B.,Shanghai TCM Integrated Hospital | And 12 more authors.
Journal of Long-Term Effects of Medical Implants | Year: 2016

The reconstruction of the right ventricular outflow tract (RVOT) system represents a considerable challenge for both manufacturers and surgeons because the patients requiring this type of devices have a very diverse set of anatomical challenges that can lead to complications and subsequent early device failures. We conducted an in-depth investigation of a porcine-valve conduit explanted from a patient following an adverse event. A control device was analyzed as a reference. The rapid aging of the porcine valve in the right side of the heart together with major thrombus formation raises several questions. The difficulties encountered with materials used and also the design features of the conduits are once again highlighted. This group of patients continues to increase in number due to success in the surgical outcomes in early childhood. Therefore, there is a greater demand for an appropriate device. However, much work is still needed to achieve this goal, and the best approach to achieving success remains unanswered. © 2016 by Begell House, Inc.

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