Jbail, Lebanon

The Lebanese American University is a secular, private and independent American university and research institution located in Lebanon. The university is chartered by the Board of Regents of the University of the State of New York and is accredited by the Commission on Institutions of Higher Education of the New England Association of Schools and Colleges . It is composed of two campuses, one in Beirut and the other in Byblos, and offers programs leading to degrees in Arts, Business, Engineering, Nursing, science, Pharmacy, and Medicine.LAU is governed by a Board of Trustees that oversees the primary functions of leadership, stewardship and audit. A Board of International Advisors provides counsel on university policies and other matters to the Board of Trustees, president, and senior management. Wikipedia.

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Agency: Cordis | Branch: FP7 | Program: CP-FP-SICA | Phase: SSH.2013.4.1-2 | Award Amount: 3.12M | Year: 2014

Young people in the South and East Mediterranean area are enduring a multiple transitions. In addition to the political and socioeconomic transformations, there is the transition to adulthood from the famous tripartite division of the life cycle in preparation for professional life, working life and retirement. Other experiences of socio-economic transformation, as in East Europe, may give us learnt lessons to manage economic, political and social change. Today, there are no longer substantial differences separating the young people of west and east. Nevertheless, there are important differences in economic resources, education and social between two shores of the Mediterranean. In addition, the SEM young Europeans differ in cultural values and practices different from their counterparts in the north. Still, some processes linked to economic globalization and the precarious living conditions, labor and difficulties in individual empowerment, among others, suggest the emergence of a youth crime and its consolidation as a category of scientific analysis. This argument lets you put so research that supports integrating the European experiences in youth employment, political participation and gender equality, the youth situation in the context of transition and European double in similar scenarios on the south bank. To articulate such research dimensions the project will articulate the concept of triple transition, taking into account political transitions, socio-economic transitions, and invisible transition such as cultural trends and emotions related to youth and the insecurity about the future (resident generation)

Khabbaz M.J.,Concordia University at Montréal | Assi C.M.,Concordia University at Montréal | Fawaz W.F.,Lebanese American University
IEEE Communications Surveys and Tutorials | Year: 2012

Nowadays, wireless networks are witnessing several deployments in various extreme environments where they suffer from different levels of link disruptions depending on the severity of the operating conditions. In all cases, their operation requirements are differently altered and their performance is negatively affected rendering them heterogeneous by nature. In the open literature, these networks are known as Intermittently Connected Networks (ICNs). The existing Internet protocols fail to operate properly in the context of ICNs, thus raising a variety of new challenging problems that are attracting the attention of the networking research community. Delay-/Disruption-Tolerant Networking emerged as a highly active area of research where networking experts compete in addressing the various ICN problems. Over time, unicast routing, one of the architectural key components common to all ICNs, became an almost independent field of research in which significant efforts continue to be invested. In contrast, network architectural designs, scheduling and forwarding issues dating from the early days of Inter-Planetary Networks (IPNs) have received relatively little attention and accumulate numerous pending challenges. Moreover, the gap caused by the lack of accurate ICN mathematical models is still large irrespective of some of the appreciated seminal works in this direction. This paper sheds the light over the latest advancements in each of the above-mentioned research sectors and highlight pending open issues in each of them. © 1998-2012 IEEE.

El-Sibai M.,Lebanese American University
BMC complementary and alternative medicine | Year: 2014

BACKGROUND: Daucus carota L.ssp.carota (wild carrot), an herb used in folk medicine worldwide, was recently demonstrated to exhibit anticancer activity. In this study we examined the anticancer effect of Daucus carota oil extract (DCOE) fractions on the human breast adenocarcinoma cell lines MDA-MB-231 and MCF-7 and clarified the mechanism of action.METHODS AND RESULTS: Using the WST assay, the pentane fraction (F1) and 1:1 pentane:diethyl ether fraction (F2) were shown to possess the highest cytotoxicity against both cell lines. Flow cytometric analysis revealed that both fractions induced the accumulation of cells in the sub-G1 phase, increase in apoptotic cell death and chromatin condensation. The increase in apoptosis in response to treatment was also apparent in the increase in BAX and the decrease in Bcl-2 levels as well as the proteolytic cleavage of both caspase-3 and PARP as revealed by Western blot. Furthermore, treatment of MDA-MB-231 cells with either fraction significantly reduced the level of phosphorylated Erk but did not show any effect on phosphorylated Akt. The combined treatment with a potent PI3K inhibitor (wortmannin) and F1 or F2 fraction had a synergistic inhibitory effect on cell survival which shows that these two drugs work on different pathways.CONCLUSIONS: These results suggest that the pentane-based fractions of DCOE possess potential anti-cancer activity that is mainly mediated through the Erk pathway.

Tokajian S.,Lebanese American University
Clinical Microbiology and Infection | Year: 2014

Staphylococcus aureus is a bacterial pathogen that is distributed worldwide and represents an increasing problem, both in hospitals and in the community. Global transmission of methicillin-resistant S. aureus (MRSA) has been the subject of many studies. Determining the incidence of colonization with community-acquired MRSA in hospitalized patients and outpatients has been the aim of several studies conducted in the Middle East (western Asia). The local epidemiology within countries in this region is changing, owing to the introduction of new strains with the intercontinental exchange of several clones. Sequence type 80-MRSA-IV is one common clone detected in different countries within the region showing country-based differences, and hence more likely to form clonal lineages. MRSA is endemic in this region, and the burden and the difficulty in detecting imported strains are increasing. This is also increasing the risk of domestic and global transmission. To counter the threat associated with the high incidence of MRSA carriage and infections, systematic surveillance of both hospital and community isolates is required, along with appropriate measures designed to limit their spread. Additionally, antibiotic stewardship is needed to contain the further development of the observed resistance and to help in preserving antibiotics as precious therapeutic resources. It is critical for countries in this region to establish both national and international initiatives to develop better measurements designed to limit and control the spread of infections. Finally, more sequence-based studies are needed to better understand the pathogenicity and epidemiology of these important pathogens. Clinical Microbiology and Infection © 2014 European Society of Clinical Microbiology and Infectious Diseases.

Arnaout J.-P.,Lebanese American University
Journal of Intelligent Manufacturing | Year: 2013

This paper addresses the Euclidean location-allocation problem with an unknown number of facilities, and an objective of minimizing the fixed and transportation costs. This is a NP-hard problem and in this paper, a three-stage ant colony optimization (ACO) algorithm is introduced and its performance is evaluated by comparing its solutions to the solutions of genetic algorithms (GA). The results show that ACO outperformed GA and reached better solutions in a faster computational time. Furthermore, ACO was tested on the relaxed version of the problem where the number of facilities is known, and compared to existing methods in the literature. The results again confirmed the superiority of the proposed algorithm. © 2011 Springer Science+Business Media, LLC.

Saad S.S.,Lebanese American University | Nakad Z.S.,Lebanese American University
IEEE Transactions on Industrial Electronics | Year: 2011

Indoor positioning systems (IPSs) locate objects in closed structures such as office buildings, hospitals, stores, factories, and warehouses, where Global Positioning System devices generally do not work. Most available systems apply wireless concepts, optical tracking, and/or ultrasound. This paper presents a standalone IPS using radio frequency identification (RFID) technology. The concept is based on an object carrying an RFID reader module, which reads low-cost passive tags installed next to the object path. A positioning system using a Kalman filter is proposed. The inputs of the proposed algorithm are the measurements of the backscattered signal power propagated from nearby RFID tags and a tagpath position database. The proposed algorithm first estimates the location of the reader, neglecting tagreader angle-path loss. Based on the location estimate, an iterative procedure is implemented, targeting the estimation of the tagreader angle-path loss, where the latter is iteratively compensated from the received signal strength information measurement. Experimental results are presented, illustrating the high performance of the proposed positioning system. © 2010 IEEE.

Abou-Rjeily C.,Lebanese American University
Journal of Lightwave Technology | Year: 2013

In this paper, we evaluate the performance of a selective-relaying (SR) protocol that is suitable for cooperative free-space optical (FSO) communications with any number of relays. The SR strategy is based on transmitting all information symbols either along the direct link between the source and the destination or along one of the indirect links via the relays. We derive closed-form expressions of upper-bounds on the average error probability that can be achieved over Rayleigh and lognormal fading channels. We also provide an asymptotic analysis for quantifying the diversity gain and reduction in fading variance that can be realized by the cooperative scheme. The performance analysis shows the superiority of the SR scheme over the strategy that corresponds to activating all available links. © 1983-2012 IEEE.

Habchi W.,Lebanese American University
Tribology International | Year: 2014

This paper presents a finite element model for the solution of thermal elastohydrodynamic lubrication in coated circular contacts. The model is based on a full-system finite element resolution of the elastohydrodynamic and heat transfer equations. The effects of the coating's thermal and mechanical properties on lubrication performance are investigated. Two categories of surface coatings are considered based on thermal properties: high and low thermal inertia. It is found that low thermal inertia surface coatings act as insulators leading to a localized increase in the lubricant's temperature at the center of the contact. Therefore, friction can be significantly reduced while film thickness is barely affected. The opposite effect is observed for high thermal inertia coatings. These effects increase with coating's thickness. © 2014 Elsevier Ltd.

Hanna S.,Lebanese American University | El-Sibai M.,Lebanese American University
Cellular Signalling | Year: 2013

The last decades have witnessed an exponential increase in our knowledge of Rho GTPase signaling network which further highlighted the cross talk between these proteins and the complexity of their signaling pathways. In this review, we summarize the upstream and downstream players from Rho GTPases that are mainly involved in actin polymerization leading to cell motility and potentially playing a role in cancer cell metastasis. © 2013.

Abou-Rjeily C.,Lebanese American University
Journal of Lightwave Technology | Year: 2014

In this paper, we study the impact of inter-relay cooperation on the outage performance of relay-assisted free-space optical (FSO) systems with two relays. Despite the fact that in realistic networks a FSO link might be available between the deployed relays, the additional advantages of exploiting such link were never investigated before. We explore this new dimension under the two strategies where either all relays are active or a single relay is selected. We evaluate the achievable diversity orders over gamma-gamma channels and we derive conditions under which inter-relay cooperation is advantageous. We study two variants of inter-relay cooperation; namely, one-way and two-way cooperation. We prove that based on the network structure, one of these variants, both or neither may be beneficial. © 1983-2012 IEEE.

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