Ibadan, Nigeria
Ibadan, Nigeria

Lead City University is located in Ibadan, Oyo, Nigeria. It was founded on 16 February 2005 as City University but was renamed to Lead City University a month later to avoid confusion with other similarly named universities. In 2012 LCU operating license along with 6 other private universities were suspended by the National Universities Commission. The 7 universities had their suspension lifted after meeting the required requirements. Wikipedia.


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Agunbiade O.S.,Lead City University | Ojezele O.M.,U.I.P.O. Box 20711 | Ojezele J.O.,University of Ibadan | Ajayi A.Y.,Lead City University
African Health Sciences | Year: 2012

Background: Many plants with antidiabetic properties probably act in part through their content of fibre, vitamins, bioactive or mineral content Objectives: This study investigated the mineral, proximate, phytochemical compositions and hypoglycaemic effect of Commelina africana and Ageratum conyzoides extracts in diabetic rats, and the likely relationship between this property and the mineral, proximate and phytochemical compositions of the plants. Methods: The plants were subjected to mineral, proximate composition and phytochemical analysis. Attempt was made to see (if any) the relationship between the hypoglycaemic effect and the mineral, proximate compositions and phytochemistry of the plants. Alloxan-induced diabetic animals were administered 500mg/kg body weight aqueous extracts of the plants and glibenclamide as the reference hypoglycaemic agent. Results: Aqueous extract of Ageratum conyzoides reduced fasting blood glucose of experimental animals by 39.1% while Commelina africana reduced the same by 78.0%. Alkaloids, cardenolides, saponins, and tannins were detected in both plants. Anthraquinones was absent in C. africana but a trace of it was detected in A. conyzoides. The hypoglycaemic effect of Commelina africana was comparable with the reference hypoglycaemic agent. Ageratum conyzoides showed comparably weaker hypoglycaemic effect than exhibited by reference hypoglycaemic agent. Comparatively, Commelina africana had higher mineral concentrations (except Na) than Ageratum conyzoides. Conclusions: Plants' extracts minerals (magnesium, potassium and iron) and bioactive components (alkaloids and cardenolides) seemingly enhanced their hypoglycaemic effect. Furthermore, these minerals, alkaloids and cardenolides could be helpful in ameliorating complications of diabetes like hypertension and cardiovascular disease.


Abayomi A.I.,University of Ibadan | Adewoye E.O.,University of Ibadan | Olaleye S.B.,University of Ibadan | Salami A.T.,Lead City University
African Health Sciences | Year: 2011

Background: The role of vitamins and mineral supplementation in the prevention of diabetes mellitus is not well elucidated. Objective: The effect of prior administration of magnesium on alloxan induced diabetes was assessed in rats. Methods: 36 Male albino rats were used for this study. The animals were divided into 6 groups of 6 animals each; group 1 was healthy control; groups 2 served as diabetic control. Animals in group 3 received magnesium (100 mg/kg) i.p one hour prior to alloxan (120 mg/kg) administration, group 4 were also received magnesium (150 mg/kg) i.p one hour prior to alloxan administration. Animals in group 5 received magnesium (100 mg/kg) i.p only; group 6 animals received magnesium (150 mg/kg) i.p only. Blood samples were obtained from all animals and plasma glucose levels were determined on Day 0 (prior to treatment), Day 2, Day 5, Day 7 and Day 10 after the commencement of treatment. Results: There was significant increase (P<0.001) in plasma glucose values in the alloxan treated group when compared with the control values. There was also a significant increase (P<0.01) in plasma glucose levels in the magnesium-pretreated (100 mg/kg and 150 mg/kg) diabetic groups when compared with healthy controls whereas there was a significant reduction (P<0.01) in plasma glucose level when compared with the diabetic control. Conclusion: This study has shown that magnesium pretreatment may delay the onset and subsequently cause a reduction in hyperglycemia in alloxan induced diabetes. This effect of magnesium may be attributed to its role as a scavenger of highly reactive hydroxyl radicals generated through alloxan reactions, its potentiation of glutathione antioxidant production and its role as a calcium blocker.


Oloukoi G.,Lead City University | Bob U.,University of KwaZulu - Natal | Jaggernath J.,University of KwaZulu - Natal
Health and Place | Year: 2014

This paper investigates the perceived and observed trends of associated health risks with seasonal climate variability and identifies types of and preference for adaptation strategies that are available at households and community levels in Oke-Ogun region, Nigeria. The study made use of household survey and rapid appraisal through focus group discussion and key informant interviews. For a short term climate-health impacts analysis, cases of notable diseases were correlated with monthly mean temperature and rainfall for the period 2006 and 2008. The findings show similar trends in relation to local perception on climate-health risks and observed cases of some notable diseases during seasonal changes. Diarrhea, measles and malaria were prevalent during dry season, while flu cases increased at the onset of harmattan and monsoon of rainy season. Available adaptation strategies are autonomous, mostly in the form of treatment measures such as consultation with medical officers in hospitals (17.5%), self-medication (34%) and use of traditional therapy such as herbs (48.5%). Traditional therapy is mostly preferred and approved based on long-term experience of the study population. © 2013 Elsevier Ltd.


Adeniji-Oloukoi G.,Lead City University | Urmilla B.,University of KwaZulu - Natal | Vadi M.,University of KwaZulu - Natal
Environmental Development | Year: 2013

This paper identifies types of coping strategies that are available during water supply shortages to households in Oke-Ogun, Nigeria; investigates the adequacy and effectiveness of coping options and identifies why different population group prefer one particular coping strategy over another. This work also investigates how household socioeconomic status influence the choice of coping strategies during water supply shortages in local communities that do not have formal water utilities. Data was collected via site visits to three local communities in the region, a household survey of 397 respondents, key-informant interviews and focus group discussions. Observed and perceived trends of climate indicate variability with impacts on drying of wells which are the main water supply sources almost immediately after the wet season. During periods of water scarcity, most households combined multiple coping strategies. Yet, 90% of the participating households indicated that available coping strategies are not adequate. Households in traditional compounds rely more on behavioural coping options while households in newer planned neighbourhoods depend on technical coping options. The choice of hard coping options depends on households' socioeconomic characteristics with income as the most influential factor. © 2012 Elsevier B.V.


Adeosun A.M.,Lead City University | Oni S.O.,Lead City University | Ighodaro O.M.,Lead City University | Durosinlorun O.H.,Lead City University | Oyedele O.M.,Lead City University
Journal of Taibah University Medical Sciences | Year: 2016

Objectives Phoenix dactilyfera L (date palm) seeds are used in traditional medicine for the treatment of several ailments. These seeds have been shown to lower the risk of cancer and some cardiovascular conditions as well as to improve the functionality and integrity of the immune system. On the basis of established associations between the composition of plants and their therapeutic or biological effects, this study sought to investigate the phytochemical, mineral, and antioxidant profiles of the date palm seed. Methods The phytochemical and mineral compositions as well as the free radical scavenging capacity of the date palm seed were evaluated using standard protocols. Results The alkaloids, flavonoids, anthraquinones, saponins, terpenoids, and tannins contents (mg/100 g dry weight) were 102.27 Atropine equivalents (ATE), 2471.23 Quercetin equivalents (QE), 334.93 Alizarin equivalents (ALE), 124.41, 19.47, and 133.20, respectively. The sodium, potassium, calcium, magnesium, iron, phosphorus, and zinc contents (mg/100 g dry weight) were 0.67, 78.12, 18.20, 0.48, 0.82, 19.32, and 0.25, respectively. The scavenging activities (EC50) of the seed against 1,1-diphenyl-2-picryl hydrazyl (DPPH) and superoxide dismutase (SOD)-generated free radicals were 10.21 mg/mL and 1.67 mg/mL respectively. Conclusions This study concluded that the date palm seed is rich in flavonoids, a group of polyphenolic antioxidants that are apparently responsible for the appreciable free radical scavenging effects. The polyphenolic compounds present in the investigated date seed may account for its therapeutic relevance in traditional medicines. © 2015 The Authors.


Nigerian stakeholders have frequently bemoaned the mass failure of students in English language in communication situations and as a qualifying subject. Computer-Assisted Language Learning has been proved to be a sure panacea to the problem. But studies have revealed language teachers' gross lack of knowledge of computer literacy. This study, therefore, examined the adequacy of computer literacy contents of the curricula of the university departments training English language teachers. Since it has been generally acknowledged in Nigeria that privately owned establishments provide higher quality services than their publicly owned counterparts, the study also examined computer in language teacher training from the angle of public-private ownership dichotomy. Copies of a self-constructed nineteen-item questionnaire were administered after obtaining a validity of 0.85 Cronbach alpha. The data collected from a total of two hundred and eleven pre-service English language teachers from two public universities and two private ones through stratified random sampling were analysed with the statistical tools of frequency counts, simple percentages and chi-square. The findings revealed that: (i) a Nigerian preservice English language teachers is offered at least a computer course (ii) private universities offer more computer literacy courses to their pre-service English language teachers than public universities (iii) the computer literacy courses offered to them in Nigerian universities lack pedagogical contents (iv) private universities provide more computer facilities for their pre-service English language teachers than the public ones do (v) those in private universities rate their institutions' computer literacy programmes higher than their counterparts in public ones rate theirs. © EuroJournals Publishing, Inc. 2011.


Ladokun O.,Lead City University | Ojezele M.,Lead City University | Arojojoye O.,Lead City University
African Health Sciences | Year: 2015

Background: The extract of the leaves of Viscum album (mistletoe) has been used for centuries in traditional medicine in many parts of the world. However, like many medicinal plants, the belief that things of natural origin are safe may not be entirely true. The blood is a good indicator of health and pathological mirror of the entire body. Objective: Therefore, in this study, the acute effects of extracts of mistletoe, harvested from three hosts, on haematology indices of wistar albino rats was investigated. Methods: Graded doses (400, 800, 1600 and 3200mg/kg body weight) of aqueous extracts of mistletoe from three different host plants, coffee (Coffee arabica), kola (Kola nitida), cocoa (Theobromae cacao), were administered orally to wistar albino rats for 14 days. Full haematological parameters were evaluated on whole blood collected from rats twenty four hours after the administration of the last dose. Results: Mistletoe from kola caused a concentration dependent and statistically significant (p<0.05) reduction in platelets count in rats. Administration of mistletoe extract from cocoa and coffee led to reduction in hemoglobin concentration. Reductions in packed cell volume (PCV) and red blood cell (RBC) and increase in white blood cells (WBC) were also observed in rats administered all the extracts. Conclusion: Increase in the WBC count observed in rats administered mistletoe suggests that mistletoe extract contains agents that could stimulate the production of leucocytes and could serve as immune booster. However, there is need to be cautious in administration at high doses to prevent the risk of anaemia. © 2015 Makerere University, Medical School. All rights reserved.


Achimugu P.,Lead City University | Soriyan A.,Obafemi Awolowo | Oluwagbemi O.,Lead City University | Ajayi A.,Obafemi Awolowo
Studies in Health Technology and Informatics | Year: 2010

In the health sector, record linkage is of paramount importance as clinical data can be distributed across different data repositories leading to duplication. Record Linkage is the process of tracking duplicate records that actually refers to the same entity. This paper proposes a fast and efficient method for duplicates detection within the healthcare domain. The first step is to standardize the data in the database using SQL. The second is to match similar pair records, and third step is to organize records into match and non-match status. The system was developed in Unified Modeling Language and Java. In the batch analysis of 31, 177 "supposedly" distinct identities, our method isolates 25, 117 true unique records and 6, 060 suspected duplicates using a healthcare system called MINPHIS (Made in Nigeria Primary Healthcare Information System) as the test bed. © 2010 IMIA and SAHIA. All rights reserved.


PubMed | Lead City University
Type: Journal Article | Journal: Acta scientiarum polonorum. Technologia alimentaria | Year: 2017

Regular consumption of vegetables has been associated with reduced risk of chronic diseases. The phenolic and free radical scavenging properties of five green vegetables grown in southern Nigeria were determined.The phenolic and antioxidant profile of African spinach, bitter leaf, jute leaf, scent leaf and water leaf harvested in the month of August were assessed using standard protocols.The total phenolic content (GAE mg/100 g) of the fresh vegetables ranges from 738.70 7.90 in African spinach to 1464.63 7.60 in scent leaf. A higher flavonoid content (QE mg/100 g) was found in water leaf (512.07 1.47) and jute leaf (510.13 2.22) compared to the other vegetables examined; scent leaf (496.51 1.31), African spinach (457.40 1.50), bitter leaf (371.89 0.44). Scent leaf possesses the highest DPPH radical scavenging activity with an EC50 [g/mL] of 74.64 7.73. The other vegetables show a lower EC50 [g/mL]; jute leaf (125.86 11.34) > water leaf (132.43 9.43) > bitter leaf (156.02 5.43) > African spinach (213.44 9.29). The hydroxyl radical scavenging activity (EC50, g/mL) of the vegetables in order of decreasing activity, was bitter leaf (50.38 7.17) > water leaf (103.41 6.27) > African spinach (110.548.15) > jute leaf (144.39 9.37) > scent leaf (217.51 6.90). The total antioxidant capacity (EC50, g/mL) of the vegetables increases in the following order; African spinach (227.39 7.25) < bitter leaf (169.966.86) < water leaf (106.31 7.66) < scent leaf (65.47 14.43) < jute leaf (27.52 4.14).The green vegetables possess appreciable phenolic and antioxidant potentials, which underscore their regular consumption as part of healthy Nigerian diet. Principal component analysis (PCA) buttresses the correlations and variations of the aforementioned potential among vegetable species.


PubMed | Lead City University
Type: Journal Article | Journal: Journal of forensic nursing | Year: 2016

Active shooter incidents have been on the rise in the United States in the last 2 decades, specifically events occurring in public areas traditionally considered safe such as churches, schools, and hospitals. An examination of historical events shows that the emergency department (ED) nurse must be equipped to handle any situation that may arise, including the increasing likelihood of an active shooter situation. Hospital response to these occurrences is changing, and protocols for staff response are being adjusted on a regular basis. Immediate response, postevent actions, and evidence collection procedures must be a part of the ED nurses ongoing education. Lessons learned from events that have occurred must be examined so ED nurses can be more aware and ready to respond to the increasing chance of an event such as this occurring in their ED.

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