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Dolan J.W.,LC Resources
LC-GC Europe | Year: 2015

Unexpected results from calibration standards create confusion in a clinical liquid chromatography (LC) method. © 2015, Advanstar Communications Inc. All rights reserved. Source


Dolan J.W.,LC Resources
LC-GC Europe | Year: 2015

How to distinguish between liquid chromatography (LC) column overload and detector overload. For many applications of liquid chromatography (LC), the goal is to measure very small quantities of the analytes of interest. In such cases, the problems associated with too much sample are rarely encountered. However, problems at the other end of the scale exist when more of an analyte is present than can be accommodated by the LC system. This situation is usually referred to as overload. Overload most commonly occurs as column overload or detector overload. This month’s “LC Troubleshooting” article looks at these two overload types, their causes, and possible solutions to correct the problem. © 2015 Advanstar Communications Inc. All rights reserved. Source


Dolan J.W.,LC Resources
LC-GC Europe | Year: 2014

If scaling isocratic separations is so simple, why is gradient scaling so confusing?. © 2014, Advanstar Communications Inc. All rights reserved. Source


Dolan J.W.,LC Resources
LC-GC Europe | Year: 2016

A reliable autosampler is one key requirement for unattended operation of a liquid chromatograph. © 2016, Advanstar Communications Inc. All rights reserved. Source


Dolan J.W.,LC Resources
LC-GC Europe | Year: 2016

Different techniques of liquid chromatography (LC) mobile-phase mixing can give different results and have different problems. © 2016 Advanstar Communications Inc. All rights reserved. Source

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