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Khuje P.D.,Chirayu Medical College and Hospital | Hulke S.M.,Laxminarayan Medical College
Research Journal of Pharmaceutical, Biological and Chemical Sciences | Year: 2012

Though instrumental music is at least 40,000 years old but physical principles governing sound production and the physiological variables during the performance are now being studied scientifically. Our study's purpose was to investigate the effect of playing a particular wind instrument on PFT. This was cross-sectional study done 56 clarinet and 58 trumpet players. Pulmonary function test was done using HELIOS 401 RMS medspiror. Graph pad prism5 software. Unpaired t test for lung function parameter. Showed significant increase in FVC, FEV1, PEFR, FEF25%, FEF 50 %, FEF25-75% and MVV in clarinet players, however no significant change was observed in FEV1/FVC% ́ FEF75%. The Clarinet players had higher pulmonary functions than the trumpet players. Source


Manohar Patil D.,maiya Medical College and Research Center | Mali S.,maiya Medical College and Research Center | Dalvi V.,maiya Medical College and Research Center | Meghnad Hulke S.,Laxminarayan Medical College
Research Journal of Pharmaceutical, Biological and Chemical Sciences | Year: 2012

According to The Medical Council of India, under "Regulations on Medical Education, 1997, there is scope for trying innovative approaches. They had also observed that lectures alone are not generally adequate as a method of training. To investigate the role of quiz as a learning Tool in Medical Education and to find out whether quiz can serve as an active learning method to medical undergraduates. The present study is a Descriptive study involving First year MBBS students conducted in the department of Physiology. The response scores were expressed in the figures for both participants and for audience separately. Statistical analysis used: one way ANOVA using Graph Padprism5 software. For the participants, (91.66%) like the quiz, (91.66%) found time for the Quiz was adequate, (91.66%) found the Quiz useful for learning, (91.66%) boosted their confidence. For the audience (95.55%) like the quiz, (86.66%) found time for the Quiz was adequate, (88.89%) found the Quiz useful for learning. This approach ensured active learning with greater participation of the students in acquiring knowledge. The performance of the students and their participation was very much encouraging. Source


Shete S.A.,Jhalawar Medical College | Hulke S.M.,Laxminarayan Medical College | Thakare A.,Laxminarayan Medical College | Patil P.,Laxminarayan Medical College | Kaore K.,Government Medical College
Research Journal of Pharmaceutical, Biological and Chemical Sciences | Year: 2012

In recent years, it is evident from different studies that oxidative stress has a definite role in inducing male infertility. Antioxidants help to fight against the oxidative stress. To estimate the levels of antioxidants viz. ascorbic acid (vitamin C), alpha-tocopherol (vitamin E) and reduced glutathione (GSH) in the seminal plasma of human subjects with different fertility potential. The present study was done on four groups. Four groups were group 1- control (n=10) normozoospermic fertile, group2: Normozoospermics (n=20) infertile, group 3-oligoasthenoteratozoospermics (n=30) infertile, and group 4- Asthenoteratozoospermics (n=20) infertile. Their semen analysis was done and levels of the antioxidant Vitamin C, Vitamin E, and the reduced glutathione was measured. ANOVA test and Bonferroni's post test. Coefficient of correlation (r- value) was found to find relationship between different parameters. Ascorbic acid, α -tocopherol and reduced glutathione level (GSH) was significantly more in group 1 as compared to the other groups. Ascorbic acid, α -tocopherol and reduced glutathione level levels of seminal plasma were found to be positively correlated with sperm concentration (r = 0.63, r = 0.73, r = 0.55, r = 0.57), sperm motility (r = 0.44, r = 0.51, r = 0.57 r = 0.59), normal sperm morphology (r = 0.72, r = 0.63, r = 0.73, r = 0.59). Decreasing seminal plasma antioxidants levels could have significant role in etiology of impaired sperm function. Seminal plasma antioxidants levels is closely related to male fertility, and the decreased level of antioxidants levels in seminal plasma may be one of the causes of male infertility. Source


Shete S.,Jhalawar Medical College | Hulke S.M.,Laxminarayan Medical College | Thakare A.,Laxminarayan Medical College | Patil P.,Laxminarayan Medical College
National Journal of Physiology, Pharmacy and Pharmacology | Year: 2012

Background: Sperm function testing is used to determine if the sperm have the biologic capacity to perform the tasks necessary to reach and fertilize ova and ultimately result in live births. There is growing evidence that damage to spermatozoa by reactive oxygen species may affect sperm function and Antioxidant help to fight against such reactive oxidant species. Aims & Objective: To find the correlation between antioxidants and sperm function tests. Materials and Methods: Cross section study done on four group with different fertility potential. Four groups were group 1- control(n=10) normozoospermic fertile, group2-: Normozoospermics (n=18) infertile, group 3-oligoasthenoteratozoospermics (n=27) infertile, and group 4-Asthenoteratozoospermics (n=23) infertile. Their semen analysis was done and levels of the antioxidant Vitamin C, Vitamin E, and the reduced glutathione was measured. Correlation was found between sperm function test and antioxidant level in seminal plasma. Statistical analysis was done using ANOVA test and Bonferroni's post test. Coefficient of correlation (r- value) was found to find relationship between different parameters. Graphpad prism 5 Software was used. Results: Sperm function test and antioxidant level in seminal plasma was significantly more in group 1 as compared to the other groups. Significant correlation was seen between sperm function test and antioxidant level. Conclusion: Decreasing seminal plasma antioxidants levels could have significant role in etiology of impaired sperm function. Seminal plasma antioxidants levels is closely related to male fertility, and the decreased level of antioxidants levels in seminal plasma may be one of the causes of male infertility. Source


Patil P.,Laxminarayan Medical College | Hulke S.M.,Laxminarayan Medical College | Thakare A.,Laxminarayan Medical College
Research Journal of Pharmaceutical, Biological and Chemical Sciences | Year: 2012

Formalin is used in gross anatomy laboratories as a preservative of biological specimen as well as cadavers. Medical students specially 1st year are exposed to vapours emitted during dissection. To study the long term effect of formalin exposure(during dissection practical) on pulmonary function of 1st year MBBS students. This is a longitudinal study which comprises of nine months duration. Ninety six medical students [Mean (SD) age of 20.45(1.68)years] were assessed using MIR Spirolab for PFTs within 7 days of admission to their college and reexamined at the interval of three, six and nine months. Analysis was done by one way Anova test.Significant effect was seen in Forced Vital Capacity (FVC), FEV1, PEFR and FEF 25-75% at the end of nine months,however no significant change was seen over the duration of three and six month.Formalin is having adverse effects on the respiratory system over a period of nine months and we recommend a need of precautionary measures to be taken so as to decrease the exposure and also a need for multiple longitudinal studies to be done. Source

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