Laurentian University , which was incorporated on March 28, 1960, is a mid-sized bilingual university in Greater Sudbury, Ontario, Canada.While primarily focusing on undergraduate programming, Laurentian also features the east campus of Canada's newest medical school - the Northern Ontario School of Medicine, which opened in 2005. Its school of Graduate Studies offers a growing number of graduate-level degrees. Laurentian is the largest bilingual provider of distance education in Canada. Wikipedia.
Persinger M.A.,Laurentian University
Current Medicinal Chemistry | Year: 2010
The myriads of molecular pathways that have been measured to understand the physical bases of neuronal and other cellular functions have exceeded classical comprehension. In the tradition of Bohr and Schrodinger, the hypothesis is developed that molecular pathways are simply epiphenomenal transports of quanta with increments in the order of 10-20 J. Experimental measurements of photon emissions from cell cultures and the serial steps of phosphorylation in general molecular pathways and transformations in chromophores supported this contention. This discrete value is also associated with action potentials, intersynaptic events, the biophysical bases of membrane potentials, the numbers of action potentials per cell from magnetic energy potential, and the interionic distances around membranes. Consideration of information as discrete increments of energy may allow greater experimental control and external intervention of pathways relevant to medicinal chemistry. © 2010 Bentham Science Publishers Ltd. Source
Cai M.,Laurentian University
Rock Mechanics and Rock Engineering | Year: 2013
In the present study, fracture initiation and propagation from a pre-existing plane interface in a Brazilian disc is investigated using a finite-discrete element combined method. Different fracture patterns, depending on the frictional resistance of the pre-existing crack or interface, are observed from the numerical simulation. It is found that when there is no or very little frictional resistance on the surfaces of the pre-existing crack, the primary fractures (wing cracks), which are tensile in nature and are at roughly right angles to the pre-existing crack, start from the tips of the pre-existing crack. As the friction coefficient increases, the wing cracks' initiation locations deviate from the crack tips and move toward the disc center. Secondary fractures, which are also tensile in nature, initiate from the disc boundary and occur only when the length of the pre-existing crack is sufficiently long. The secondary fractures are roughly sub-parallel to the pre-existing crack. The failure load is found to be influenced by the friction coefficient of the pre-existing crack. A 38 % failure load increase can result when the friction coefficient changes from 0 to 1. A good understanding of the fracture initiation and propagation in the forms of primary and secondary fractures provides insight into explaining some fracture patterns observed underground. © 2012 Springer-Verlag Wien. Source
Laurentian University | Date: 2014-01-28
Compositions described herein are purposed to attract gravid mosquitoes to oviposit in a preferred environment. The composition for directing the oviposition of mosquitoes comprises one or more attractants and NPK additive, wherein the NPK additive is mixture that contain chemical elements nitrogen, phosphorus and potassium. The attractants can be modified to provide a composition for facilitating the oviposition of different kind of mosquito. The composition described above, can be modified to provide a composition for facilitating the oviposition of the
Rna Diagnostics Inc. and Laurentian University | Date: 2011-08-10
Provided are methods of determining a response to a chemotherapeutic agent in a subject with ovarian cancer, comprising: determining a RNA integrity value of a sample comprising ovarian cancer cell RNA from the subject after the subject has received one or more doses of the chemotherapeutic agent; wherein a low RNA integrity value and/or RNA degradation of the cancer cell RNA is indicative that the cancer is responding to the chemotherapeutic agent and/or a high RNA integrity value and/or stable RNA integrity of the ovarian cancer cell RNA is indicative that the cancer is resistant to the chemotherapeutic agent.
Laurentian University | Date: 2010-05-04
Formulations are provided for producing structural members or back fill for mine stopes in environments having sub zero temperatures such as permafrost. The formulations having constituents including crushed rock (rockfill), powdered tailings, ice and water in specific ratios with attention to the prescribed gradations of the rockfill and tailings. The tailings, a readily available and very finely divided material, fill the naturally existing voids in the rockfill. The gradation of the rockfill and the bulk density of the rockfill establish the rockfill/tailings ratio, which has been determined to lie between 1 and 3 or from 50/50 to about 75/25 for optimum strength. The ice in the mix design arises from the pre-existing moisture content in the rock and tailings typically 2% to 5% for the rockfill, 8% to 25% for the tailings. The change of state of liquid water to ice on the particle surfaces is the binding mechanism of the system and is enhanced by vigorous mixing.