Lambung Mangkurat University is a public university in Banjarmasin and Banjarbaru, South Kalimantan, Indonesia. It is established on September 1, 1958. Its current rector is Prof. Dr. Ir. H. Muhammad Ruslan, M.S. It is named after Lambung Mangkurat, the first Negara Dipa's patih . Wikipedia.
Marisa D.,Lambung Mangkurat University |
Rudito M.,Lambung Mangkurat University |
Zagita M.G.,Lambung Mangkurat University |
Biworo A.,Lambung Mangkurat University |
Suhartono E.,Lambung Mangkurat University
International Journal of Toxicological and Pharmacological Research | Year: 2016
In this present study, we try to investigate the hepatotoxicity effect of RIF and INH vis chlorinative stress pathway in vitro, by measured catalase (CAT) kinetic parameters and Advanced Oxidation Protein Products (AOPPs) level. In this experiment, a liver sample was taken from male rats (Rattus novergicus). Sample the homogenized and divided into three groups with; T0 served as control which contains liver, T1 which contains liver homogenate + 450 mg Rifampicin (RIF); and T2 which contains liver + 300 mg Isoniazid (INH). For CAT kinetic parameters analysis (Km, Vmax, and kcat), in each solution was added hydrogen peroxide (H2O2) with different concentrations. Solutions then incubated at 37ºC for 1 hours and then was prepared for kinetic parameter analysis. The AOPPs level was analysed using spectrophotometric methods. The results showed that both RIF and INH treatments could decrease the affinity of H2O2-CAT complex and increase the turnover rate of the reaction which expressed by the higher Km, Vmax, and kcat values. Also, the results showed that both RIF and INH significantly increased the level of AOPPs in liver homogenate. From this results, it can be concluded that both RIF and INH-induced hepatotoxicity via chlorinative stress pathway by disrupting the CAT activity and increased the AOPPs level. © 2016, International Journal of Toxicological and Pharmacological Research. All rights reserved.
Hidayat A.S.,Lambung Mangkurat University
AACL Bioflux | Year: 2017
This study was intended to identify the shrimp culture condition, analyze the shrimp farmer’s problems, and create the concept of the development strategy. It was carried out in Muara Kintap village, Tanah Laut regency. It applied SWOT analysis on the internal and external factors. Results showed that the shrimp pond condition got very strong environmental pressure from various mining and plantation activities nearby so that the shrimp culture could not productively work. SWOT analysis found that shrimp pond culture was in quadrant IV (FSI -0.21 and FSE -0.71) reflecting weak position due to very strong external environmental threat in which the internal force was not capable enough of controlling it or being in defensive strategy. Pond culture development in the study site could be done through revitalization and conservation of protected area and mangrove, and access limitation to the coastal area. Stakeholder’s role and concern for coastal and marine environmental preservation is needed in order to support the productive economic development of local communities, especially fisheries and promote community’s participation in the management of aquatic environment and mangrove ecosystem. © 2017, BIOFLUX SRL. All rights reserved.
Suhartono E.,Lambung Mangkurat University |
Iskandar,Research Unit Mutiara Bunda Mother and Child Hospital |
Santosa P.B.,Banjarbaru Forestry Research Institute
International Journal of Pharmacy and Pharmaceutical Sciences | Year: 2015
Objective: The present study was undertaken to investigate the ameliorative effect of the bark and leaves of Nothaphoebe coriacea (gemor) on Cadmium (Cd) induced glucose metabolism alteration in liver homogenate in vitro. Methods: Glucose metabolism alteration in liver homogenate was induced by the administration of Cadmium Sulphate (CdSO4) at a dose 3 mg/l. Ameliorative effect of the leaves and bark extracts was determined by assessing the concentration of glycogen, glucose and Methylglyoxal (MG). Dubois hydrolytic method was used for liver glycogen and glucose concentration estimation. Modified Dinitro Phenyl Hydrazine (DNPH) method was used for MG concentration estimation. Results: The results of this present studies showed that treatment with CdSO4 significantly decreased the levels of glycogen and MG concentration, and increased the level of glucose in liver homogenate compared to control. The aqueous extracts of bark and leaves of gemor significantly increased the levels of glycogen and MG concentration, and decreased the level of glucose in liver homogenate compared to control. The aqueous extracts of the bark of gemor in comparison with CdSO4 treatment group showed the significant effect to maintain the glycogen, glucose, and MG concentration in liver homogenate. However, when compared to the aqueous extracts of leaves of gemor the result was not significant. The results suggest aqueous extracts of the bark of gemor was more effective to prevent the glucose metabolism alteration induced by CdSO4 than the aqueous extracts of leaves of gemor. Conclusion: The present study demonstrated Cd could induced the glucose metabolism alteration in liver homogenate, and the aqueous extracts of bark and leaves of gemor showed the ameliorative effect to prevent this alteration. In addition, the bark was more effective than leaves of gemor to prevent the glucose metabolism alteration induced by Cd. © 2015, International Journal of Pharmacy and Pharmaceutical Science. All rights reserved.
Kurnain A.,Lambung Mangkurat University
International Journal of Soil Science | Year: 2016
Background: Most highly weathered soils in the tropics contain high concentration of (hydroxide) minerals, which are responsible for phosphorus adsorbed and consequently not available for plants. In practical manner Phosphorus (P) adsorption on acid mineral soils is commonly inhibited through addition of organic matters. Materials and Methods: For understanding the importance of organic matter addition on reducing P adsorption, this study was conducted to measure P adsorption on goethite as affected by humic acids and compare the result with P adsorption on acid mineral soil. Phosphorus adsorption to the goethite was studied by a bath method. A serie of phosphorus solution of 0.1-0.75 mM phosphorus and 0.1 and 0.3 g L-1 humic acids was added to 1 g L-1 goethite suspension in background electrolyte of 0.01 M NaNO3 in which its pH was adjusted to certain range of pH with adding acid or alkaline solution. Results: In the absence of humic acids P adsorption to goethite was more pH-dependent than in the presence of humic acids. Conclusion: This implies that there is a change in charging behaviour of goethite due to the concomitant or previous adsorption of humic acid on goethite. Humic acid reduces P adsorption on goethite much more pronounced at pH<6, suggesting that in the normal pH,humic acid is very important to make phosphate more available for plants. The result was consistent with increasing P adsorption on acid soil from the top soil layer previously leached by rainfall. © 2016 Ahmad Kurnain.
Rodiansono R.,Lambung Mangkurat University |
Shimazu S.,Chiba University
Bulletin of Chemical Reaction Engineering and Catalysis | Year: 2013
Effective production of hexitols (sorbitol and mannitol) was achieved from sugars by means of nickel nano-particles supported on aluminium hydroxide (NiNPs/AlOH) catalyst. NiNPs/AlOH catalyst was prepared by a simple and benign environmentally procedure using less amount of sodium hydroxide. ICP-AES and XRD analyses confirmed that the NiNPs/AlOH catalysts comprised a large amount of remained aluminium hy-droxide (i.e. bayerite and gibbsite). The presence of aluminium hydroxide caused a high dispersion Ni metal species. The average Ni crystallite sizes that derived from the Scherrer's equation for former R-Ni and NiNPs/AlOH were 8.6 nm and 4.1 nm, respectively. The catalyst exhibited high activity and selectivity both hydrogenolysis of disaccharides (sucrose and cellobiose) and monosaccharides (glucose, fructose, and xylose) at 403 K for 24 h. The NiNPs/AlOH catalyst was found to be reusable for at least five consecutive runs without any significant loss of activity and selectivity. © 2013 BCREC UNDIP.
Noor Z.,Lambung Mangkurat University
Journal of Osteoporosis | Year: 2013
Hydroxyapatite is chemically related to the inorganic component of bone matrix as a complex structure with the formula of Ca10(OH) 2(PO4)6. Previous studies have reported the application of microsized hydroxyapatite to bone regeneration, but the result is not satisfied. The limitation comes from the size of hydroxyapatite. In addition, the duration of treatment is very long. The advantages of hydroxyapatite nanocrystal are the osteoconduction, bioresorption, and contact in close distance. Crystal in osteoporotic bone is calcium phosphate hydroxide with the chemical formula of Ca10(OH)2(PO 4)6. Crystal of normal bone is sodium calcium hydrogen carbonate phosphate hydrate with the chemical formula of Ca8H 2(PO4)6·H2O-NaHCO 3-H2O. The recent development is applying nanobiology approach to hydroxyapatite. This is based on the concept that the mineral atoms arranged in a crystal structure of hydroxyapatite can be substituted or incorporated by the other mineral atoms. In conclusion, the basic elements of hydroxyapatite crystals, composed of atomic minerals in a certain geometric pattern, and their relationship to the bone cell biological activity have opened opportunities for hydroxyapatite crystals supplement application on osteoporosis. Understanding of the characteristics of bone hydroxyapatite crystals as well as the behavior of mineral atom in the substitution will have a better impact on the management of osteoporosis. © 2013 Zairin Noor.
Amrullah A.,Lambung Mangkurat University
International Journal of Manufacturing, Materials, and Mechanical Engineering | Year: 2016
Currently the use of motor gasoline from year to year increase. In 2010 the number of vehicles in Indonesia about 26,706,705 vehicles, in 2011 amounted to 30,769,093 vehicles and 2012 amounted to 38,156,278 vehicles. This resulted in the consumption of petroleum fuels and exhaust emissions in motor vehicles is increasing. To overcome these problems, conducted research on synthetic fuel which is one of the alternative fuel sources. This research was conducted at gasoline engine. Variations in fuel mixture gasoline and synthetic fuel. This research will be able to generate and determine the effect of fuel mixture gasoline-synthetic fuel on levels of exhaust emissions, to determine the effect of fuel mixture gasoline-synthetic fuel for engine performance. Based on the analysis of performance and exhaust emissions test on a gasoline engine, for most engine performance is good and efficient set at first to mix synthetic fuel. © 2016, IGI Global. Copying or distributing in print or electronic forms without written permission of IGI Global is prohibited.
Chotimah C.,Brawijaya University |
Ciptadi G.,Brawijaya University |
Setiawan B.,Lambung Mangkurat University |
Fatchiyah F.,Brawijaya University
Asian Pacific Journal of Tropical Disease | Year: 2015
Objective: To investigate whether the CNS1S2 protein of goat milk is able to inhibit the toxicity of methyl glyoxal (MG) towards MC3T3E1 pre-osteoblast cells. Methods: At confluency, pre-osteoblast cells were divided into five groups which included control (untreated), pre-osteoblast cells exposed to 5 μmol/L MG, pre-osteoblast cells exposed to MG in the presence of CSN1S2 protein at doses of 0.025, 0.050, and 0.100 mg/L, respectively. Analysis of reactive oxygen species was done with 2,7-dichlorodihydrofluorescein diacetate fluorochrome. The proliferation and viability of MC3T3E1 cells were measured by trypan blue staining. Malondialdehyde analysis was done colorimetrically. Results: Cell's viabilities were significantly lower in MG+0.050 mg/L CSN1S2 protein of goat milk compared to MG group (P<0.05). MG+0.100 mg/L CSN1S2 protein of goat milk significantly increased the cells viability compared to MG group (P<0.05). The levels of proliferation were significantly higher in MG+0.100 mg/L CSN1S2 protein of goat milk compared to control group and all treatment groups, respectively (P<0.05). Conclusions: High dose of CSN1S2 protein of goat milk (0.100 mg/L) in high MG environment inhibits the decrease of viability due to the increases of the proliferation of MC3T3E1 pre-osteoblast cell. © by the Asian Pacific Journal of Tropical Disease.
Rifa'i M.A.,Lambung Mangkurat University
AACL Bioflux | Year: 2016
The depth of waters has a close correlation with intensity of sunlight and waters’ temperature. The deeper the waters from the surface, the less light intensity be received. As a result, temperature also decreases at the deeper layer. This certainly gives effect on the abundance and the body size of giant sea anemones. The purpose of this study is to find out the relationship of the depth of waters to the distribution of abundance and body size of the giant sea anemones in the waters of Teluk Tamiang village, south Kalimantan, Indonesia. Study sites were divided into five stations: three stations in the western part of the waters and two stations in the eastern part of the waters of Teluk Tamiang. Each station was subdivided into three depths: 0-2 m, > 2-4 m, and > 4-6 m. Data of relative abundance and body size of giant sea anemones at different depths were analyzed using Kruskal Wallis test. Distribution of abundance and body size of giant sea anemones based on depths was analyzed using Correspondence Analysis. The results showed that there were three species of giant sea anemones found, namely Stichodactyla gigantea, Entacmaea quadricolor and Heteractis crispa. The abundance and body size of S. gigantea were higher than those of E. quadricolor and H. crispa. However, the distribution of abundance and body size anemones had no significant difference among the depths of waters. © 2016, BIOFLUX SRL. All rights reserved.
Itta D.,Lambung Mangkurat University
International Journal of ChemTech Research | Year: 2016
One effort to maintain C stockvegetativelyin nature is thr1ough agroforestry program on peatland. Through agroforestry system the concentration of CO2 in the atmosphere can be reduced, and the result is carbohydrate accumulated in plant biomass. The level of CO2uptake in the atmosphere varies depending on the typesof constituent plantsand the age ofland.The objectives of this study wereto analyze 1) the carbon content stored in agroforestry system on peatland, 2) the ability of agroforestry system on peatland to absorb carbon emission (CO2), 3)the economic value through agroforestry on peatland. The benefits of this study were to provide important information in the effort torehabilitate the degraded peatland,which was developed through agroforestry system. Moreover, the results of this study could be used as the reference data to implement the program ofReducing Emission from Deforestation and Degradation (REDD). The results showed that 1) the number of carbon content for jelutung plants in agroforestry pattern was 1.4430 tons/ha,and for intercrops4.185 tons/ha which consisted of corn, mustard, chili and leek,2) the ability of staple crops and intercrops to absorb CO2in agroforestry patternwas20.496 tons/ha, and 3) the benefit valuewhich wasobtained by agroforestrypattern on peatland wasIDR 375,322,625 in a year, where the intercrops could be cultivatedseveral times a year. It is suggested to conductfurther study to calculate the carbon content of staple crops andintercrops and the ability ofother staple crops and intercrops to absorb CO2. © 2016, Sphinx Knowledge House. All rights reserved.