Lahore College for Women University
Sita Road, Pakistan

Lahore College for Women University is an independent women's university in Lahore, Pakistan, founded as a women's college in 1922. One of the oldest female institutions of Pakistan, the university has 15,000 students and a teaching faculty of 450. It admits students at the intermediate,bachelors level master's and Ph.D. levels. Established in May 1922 as an intermediate residential college, it was housed in a building on Hall Road, Lahore, with a strength of 60 students, 25 of whom were boarders and 13 staff members.As per ranking of general universities, Higher Education Commission of Pakistan ranks Lahore College for Women University at 15. Wikipedia.

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We determined the correlation between a pesticide exposure, physical health and susceptibility toward tuberculosis along with hematological indices and liver enzymes’ alterations in sprayers exposed to pesticides. Molecular detection of Mycobacterium tuberculosis and Mycobacterium bovis was detected by targeting histone-like protein (hupB) gene. The WBC (white blood cells) and RBC (red blood cells) levels of male sprayers and non-sprayers were significantly different (P<0.05). In female spray workers, the WBC and neutrophils levels were significantly different as compared with non-sprayers. Overall, in both male and female pesticide-exposed sprayers, mean values of alanine amino transferase and aspartate amino transferase were higher as compared with unexposed workers. M. Tuberculosis were detected in 15% male sprayers and 36% female sprayers while, M. bovis was detected in 5% male sprayers and 10% female sprayers. A χ2-test indicated that there existed a significant different (P<0.05) between positive and negative M. tuberculosis and M. bovis in both male/female spray workers out of total. The susceptibility of pesticide-exposed sprayers to tuberculosis and alterations in hematology and liver enzymes is crucial for health. Toxic effects of pesticides may lead to a weak immune system and increased tuberculosis susceptibility.Journal of Exposure Science and Environmental Epidemiology advance online publication, 1 February 2017; doi:10.1038/jes.2016.88. © 2017 Nature America, Inc., part of Springer Nature.

Naseem B.,Lahore College for Women University | Iftikhar M.,Lahore College for Women University
Journal of Chemical Thermodynamics | Year: 2017

The density and sound velocity for pure alcohols (methanol, ethanol, iso-propanol and n-butanol) and molal solutions of nitroimidazoles (metronidazole (MNZ) and dimetridazole (DMZ) have been measured at different temperatures (293.15–313.15 K). Different volumetric and acoustical parameters like apparent molar volume (Vϕ), partial molar volume (V˚ϕ), apparent molar isentropic compressibility (Kϕ), partial molar isentropic compressibility (K˚ϕ), hydration number (nH), acoustic impedance (Z) and intermolecular free length (Lf) of antibiotic solutions were calculated from the experimental values of density and sound velocity. The derived values have been used to explore the solute–solute and solute–solvent interactions. The Vϕ values are positive and Kϕ values are negative in both antibiotics, indicative of strong solute–solvent interactions and closely packed structure of antibiotics in alcohols. The decreasing trend of Lf with increasing antibiotic concentration shows the presence of strong intermolecular interactions in solutions. © 2016 Elsevier Ltd

Saddiqe Z.,Lahore College for Women University | Naeem I.,Lahore College for Women University | Maimoona A.,Lahore College for Women University
Journal of Ethnopharmacology | Year: 2010

Hypericum perforatum L. (Hypericaceae) is a perennial herb that is commonly known as St. John's Wort. The plant has been valued for its important biological and chemical perspectives and its use in the treatment of infectious diseases has been documented in ethnobotanical reports. Most recent interest in H. perforatum has focused on its antidepressant effects, and only recently has its antimicrobial activity been evaluated against a number of bacterial and fungal strains. The present review gives a comprehensive summary of the ethnobotanical uses, chemical constituents and biological effects (antibacterial and antifungal) of this species. A comprehensive account of the chemical constituents including anthraquinone derivatives (naphthodianthrones), flavonoids, prenylated phloroglucinols, tannins and volatile oils is also included. Various types of preparations, ointments, creams and extracts prepared with and compounds isolated from this species have been found to possess a broad spectrum of biological and pharmacological effects such as antidepressant effects, wound-healing, antiviral and antimicrobial activity. The antibacterial activity of crude extracts can be related to the use of the herb as a wound healer in ancient times. The sole antibacterial principle isolated to date is a tetraketone, hyperforin, also thought to be responsible for the antidepressant activity of the herb. The available literature indicates that it has a higher antibacterial activity against Gram-positive than Gram-negative bacteria, and alcoholic extracts (methanolic/ethanolic) were shown to possess more pronounced activity than aqueous extracts. Based on the chemical and pharmacological characteristics of H. perforatum, we concluded that this species has beneficial therapeutic properties and has the potential for use as an effective adaptogenic herbal remedy. © 2010 Elsevier Ireland Ltd.

Kalsoom Q.,Lahore College for Women University | Khanam A.,Lahore College for Women University
Journal of Cleaner Production | Year: 2017

Education for sustainable development (ESD) is transformative education aiming at developing participants’ understanding of sustainability issues and transforming their attitudes and behaviours regarding environment, society and economy. Sustainability consciousness, an expected outcome of ESD, is a complex of cognitive and affective learning. Development of sustainability consciousness requires transformative learning experiences. The study presented in this paper employed action research to enhance sustainability consciousness of the preservice teachers through inquiry based learning. The study was done in the Institute of Education, Lahore College for Women University, Pakistan. The study integrated sustainability education in an existing course entitled ‘Research Methods in Education’. The course is included in the final year of B.Ed. (Honours) programme. Outcome of the ESD-integration was measured in terms of change in the sustainability consciousness of the preservice teachers. The Action Research project engaged 27 preservice teachers in inquiry-based learning (empirical investigations and research based discussions) for a period of 11 weeks. The participants investigated sustainability issues collaboratively. To investigate the change in participants’ sustainability consciousness through inquiry based learning, researchers collected through pre- and post-tests, interviews and observation. Quantitative data were analyzed through paired t-test while qualitative data through thematic coding. The data indicate that empirical investigations into sustainability issues by the presevice teachers and research-based discussions enhanced preservice teachers’ sustainability consciousness. This highlights the transformative potential of inquiry based learning. Moreover, it indicates that sustainability education can be successfully integrated in the course of ‘research methods in education’. The findings suggest that teacher education programmes and other university programmes may employ inquiry based learning as a vehicle to enhance sustainability consciousness of the undergraduate students. © 2017 Elsevier Ltd

Riaz M.,Lahore College for Women University
Journal of Postgraduate Medical Institute | Year: 2012

Selenium is an essential trace element for humans and animals, and selenium deficiency is associated with several disease conditions such as immune impairment. Free radicals are produced in the body as a result of many biochemical processes in the body. All aerobic organisms possess antioxidant defense system to combat oxidative stress. Selenium is an important constituent of antioxidant enzymes, especially, glutathione peroxidase and some other selenoproteins that participate in various physiological activities and protects the cell against the deleterious effects of free radicals by modulating the cell response. However, their exact role is still unknown. Moreover, many human diseases are related to the cell cycle regulation. Selenium intakes, greater than the recommended daily allowance (RDA), appear to protect against certain types of cancers by finding its role in regulation of cell proliferation and apoptosis. The role of selenium has been explored in normal thyroid functioning, enhancing immune function, carcinogenesis, cardiovascular diseases, in the prevention of pre-eclampsia, diabetes mellitus and male reproduction etc. This article reviews introductory aspects of selenium as an essential micronutrient, different sources of selenium, Pharmacokinetics and its role in various pathologies and aims to provide an update on selenium profile.

Maimoona A.,Lahore College for Women University | Naeem I.,Lahore College for Women University | Saddiqe Z.,Lahore College for Women University | Jameel K.,Combined Military Hospital
Journal of Ethnopharmacology | Year: 2011

Bark extract of Pinus pinaster has a long history of ethnomedicinal use and is available commercially as herbal dietary supplement with proprietary name pycnogenol. It is used as a food supplement to overcome many degenerative disorders. Rohdewald (2002) wrote the first comprehensive review of extract highlighting its antioxidative nature and its role in different diseases. Later, Watson (2003) and Gulati (2005) in their reviews about cardiovascular health, described the extract as a best neutraceutical agent in this regard. The objective of this paper is to review the current research on this extract in terms of extraction methods, its pharmacological, toxicological and nutraceutical effects and clinical studies. Web sites of Google Scholar, Pubmed and Medline were searched for articles written in English and published in peer-reviewed journals from 2006 to 2009 and sixty-nine research articles were extracted. Of these, two are about extraction advancement and analysis while the rest relate to its clinical, biological and nutraceutical aspects. © 2010 Elsevier Ireland Ltd. All rights reserved.

Sharif M.,University of Punjab | Iftikhar S.,University of Punjab | Iftikhar S.,Lahore College for Women University
Advances in High Energy Physics | Year: 2015

This paper is devoted to studying two interesting issues of a black hole with string cloud background. Firstly, we investigate null geodesics and find unstable orbital motion of particles. Secondly, we calculate deflection angle in strong field limit. We then find positions, magnifications, and observables of relativistic images for supermassive black hole at the galactic center. We conclude that string parameter highly affects the lensing process and results turn out to be quite different from the Schwarzschild black hole. © 2015 M. Sharif and Sehrish Iftikhar.

Sarfraz M.,Kuwait University | Hussain M.Z.,University of Punjab | Hussain M.,Lahore College for Women University
International Journal of Computer Mathematics | Year: 2012

This work is a contribution towards the graphical display of 2D data when they are convex, monotone and positive. A piecewise rational function in a cubic/cubic form is proposed, which, in each interval, involves four free parameters in its construction. These four free parameters have a direct geometric interpretation, making their use straightforward. Illustrations of their effect on the shape of the rational function are given. Two of these free parameters are constrained to preserve the shape of convex, monotone and positive data, while the other two parameters are utilized for the modification of positive, monotone and convex curves to obtain a visually pleasing curve. The problem of shape preservation of data lying above a line is also discussed. The method that is presented applies equally well to data or data with derivatives. The developed scheme is computationally economical and pleasing. The error of rational interpolating function is also derived when the arbitrary function being interpolated is C3 in an interpolating interval. The order of approximation is O(hi 3). © 2012 Copyright Taylor and Francis Group, LLC.

Safa Y.,Lahore College for Women University
Desalination and Water Treatment | Year: 2016

In this research study, the biosorption of Synolon red 3HF and Synolon black HWF-FS dyes onto novel biomasses mustard oil cake and linseed oil cake, respectively, was investigated in the batch mode using different process parameters like pH, particle size, biosorbent dose, initial dye concentration, contact time, and temperature. Maximum biosorption capacity was observed at pH 1 for Synolon red 3HF onto mustard oil cake and pH 2 for Synolon black HWF-FS onto linseed oil cake. The biosorption capacity was efficient at the smallest particle size of biosorbent. The amount of dye sorbed (mg/g) decreased with the decrease in biosorbent dose and increased with increase in initial dye concentration and temperature. The Freundlich isotherm model was best fitted to experimental data. The biosorption followed the pseudo-second-order kinetic model suggesting a chemisorption mechanism. An increase of biosorption capacity with temperature shows an endothermic nature of the process. In this research, the influence of electrolytes, heavy metals, and surfactants on the removal of dyes was also examined. © 2015 Balaban Desalination Publications. All rights reserved.

In laboratory study, the entomopathogenic nematodes, Steinernema carpocapsae (Sc) and Heterorhabditis bacteriophora (Hb) alone and in combination with the insecticide, imidacloprid were evaluated against workers and nymphs of Reticulitermes flavipes (Isoptera: Rhinotermitidae). The degree of interaction varied between the two nematode species. Results revealed that different concentrations, nematode species, exposure time and interaction between entomogenous nematodes and insecticides affected termite mortality in bioassay. It was found that nematodes species Hb and Sc alone had no significant effect on termite mortality but there was synergism between imidacloprid and nematodes species that caused more than 50% mortality in most treatments within all three colonies tested. Further study is warranted on this aspect of termite research so that this synergism between nematodes and insecticides can be applied in the field to control termite colonies and as a substitute for chemical control. Copyright 2012 Zoological Society of Pakistan.

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