Kindra L.R.,University of California at Irvine |
Eggers C.J.,University of California at Irvine |
Liu A.T.,Oxford Academy |
Mendoza K.,Godinez Fundamental School |
And 3 more authors.
Analytical Chemistry | Year: 2015
Arrays of nanowires of an electronically conductive polymeric affinity medium tailored to the detection of Fe(III) are prepared, and their properties for detecting Fe(III) are evaluated. This polymeric affinity medium consists of poly(3,4-ethylenedioxythiophene) (PEDOT) into which an iron chelator, deferoxamine (DFA), has been doped during the polymerization process. PEDOT-DFA nanowires are potentiostatically deposited from a solution containing both EDOT and DFA using lithographically patterned nanowire electrodeposition (LPNE). The through-nanowire electrical resistance of PEDOT-DFA nanowires is measured as a function of the Fe(III) concentration. In parallel with measurements on PEDOT-DFA nanowire arrays, the electrochemical impedance of PEDOT-DFA films is characterized as a function of the Fe(III) concentration and the frequency of the impedance measurement in order to better understand the mechanism of transduction. PEDOT-DFA nanowires detect Fe(III) from 10-4 to 10-8 M with a limit of detection of 300 pM (calculated) and 10 nM (measured). © 2015 American Chemical Society.
Pueyo N.C.,Laguna Beach High School |
Raub A.G.,Laguna Beach High School |
Jackson S.,Laguna Beach High School |
Metz M.M.,Laguna Beach High School |
And 9 more authors.
Journal of Chemical Education | Year: 2013
A chemical research program at a public high school has been developed. The full-year Advanced Chemical Research class (ACR) in the high school enrolls 20-30 seniors each year, engaging them in long-term experimental projects. Through partnerships involving university scientists, ACR high school students have had the opportunity to explore a number of highly sophisticated original research projects. As an example of the quality of experimental work made possible through these high school-university partnerships, this article describes the development of a novel method for the oxidation of ethidium bromide, a mutagen commonly used in molecular biology. Data collected from ACR alumni show that the ACR program is instrumental in encouraging students to pursue careers in scientific fields and in creating life-long problem-solvers. © 2013 The American Chemical Society and Division of Chemical Education, Inc.