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Schmidt C.,LaGuardia Community College
Computers and Composition | Year: 2011

With the advent of GPS-enabled mobile writing devices such as smart phones and tablets, writing has become invested with a new power to express place-both through the geo-coding of one's writing location and through the presentation of place-based research on customized digital maps. This essay argues that teachers of writing must learn to accommodate and exploit these new and developing digital modalities while also making students aware of the theoretical and lived implications of digital cartographies. The essay first reviews several digital mapping projects that force their users to reconsider standard notions of place and indexicality. The essay then outlines a curriculum for teaching digital mapping in a composition-rhetoric course and presents successful examples of student work. © 2011 Elsevier Inc. Source

Radhakrishnan P.,University of Central Florida | Radhakrishnan P.,LaGuardia Community College | Fedorka K.M.,University of Central Florida
Proceedings of the Royal Society B: Biological Sciences | Year: 2012

All animals are under the constant threat of pathogenic infection. However, little is known regarding the influence of acute infection on sperm viability, particularly in female insects. This information is crucial for our understanding of mating and immune system coevolution, considering that females store sperm and serve as the site of sperm competition. Using the fruitfly, Drosophila melanogaster, we examined the influence of infection on sperm viability and storage. Twenty-four hours after haemocoel inoculation with a pathogen mimic (peptidoglycan, PGN) both sexes exhibited reduced sperm viability, indicating that systemic immune activation played a significant role in gamete survival. Surprisingly, sperm death did not appear to result from a reproductive-immune system trade-off, considering that sperm survived 24 h in vitro once removed from their somatic resources. Instead, our results are most consistent with death owing to immune effector collateral damage. We also examined the potential for sexually transmitted pathogens to influence sperm storage. Females mated with 'infected' males (created by dipping genitalia into a PGN solution) exhibited a higher proportion of empty sperm stores 48 h after mating compared to their controls. Remarkably, these data indicate that females may increase their fitness by removing 'infected' ejaculates from storage over time. © 2012 The Royal Society. Source

Rizzieri A.,LaGuardia Community College
Journal of Bioethical Inquiry | Year: 2012

I argue that embryonic stem cell research is fair to the embryo, even on the assumption that the embryo has attained full personhood and an attendant right to life at conception. This is because the only feasible alternatives open to the embryo are to exist briefly in an unconscious state and be killed or to not exist at all. Hence, one is neither depriving the embryo of an enduring life it would otherwise have had nor is one causing the embryo pain. I also argue that a rational agent in a situation relevantly similar to that of the embryo would consent to such research, and I use this insight to ground two justice-based arguments in favor of this research. © 2012 Springer Science+Business Media B.V. Source

Oulhen N.,Brown University | Onorato T.M.,Brown University | Onorato T.M.,LaGuardia Community College | Ramos I.,Brown University | And 2 more authors.
Developmental Biology | Year: 2014

Dysferlin is a calcium-binding transmembrane protein involved in membrane fusion and membrane repair. In humans, mutations in the dysferlin gene are associated with muscular dystrophy. In this study, we isolated plasma membrane-enriched fractions from full-grown immature oocytes of the sea star, and identified dysferlin by mass spectrometry analysis. The full-length dysferlin sequence is highly conserved between human and the sea star. We learned that in the sea star Patiria miniata, dysferlin RNA and protein are expressed from oogenesis to gastrulation. Interestingly, the protein is highly enriched in the plasma membrane of oocytes. Injection of a morpholino against dysferlin leads to a decrease of endocytosis in oocytes, and to a developmental arrest during gastrulation. These results suggest that dysferlin is critical for normal endocytosis during oogenesis and for embryogenesis in the sea star and that this animal may be a useful model for studying the relationship of dysferlin structure as it relates to its function. © 2014 Elsevier Inc. Source

Gelpi-Acosta C.,LaGuardia Community College
Drugs: Education, Prevention and Policy | Year: 2015

Background: Methadone maintenance treatment program (MMTP) is associated with improved quality of life amongst many heroin users. Still, program adherence problems remain a fact. Aim: To improve our understanding of MMTP "adherence problems". Methods: Using snowball sampling, two subgroups were recruited: MMTP enrollees and non-enrollees. A semi-structured questionnaire guided all in-depth interviews. Interviews were recorded, transcribed, hand-coded and analyzed using a grounded theory approach. Findings: Of 28 participants, 23 were male and Fifteen were in MMTP. All were NYC residents. Most were Hispanic (57%) and Caucasian (32%). The average age was 38 years. Twenty-two had a General Educational Development or less. All were poor and 64% were homeless. Many do not enroll in MMTP to quit heroin but to avoid physical withdrawals. Once enrolled, problems emerge with program regulations and methadones pharmacology. These they refer to as "liquid cuffs". Drawing on Michel Foucault, methadone may be considered a disciplinary biopower technology that participants challenge using specific strategies. A "Junkie" habitus, crystallized by emotional and identitarian heroin-dispositions, also challenges biopower. Conclusions: The "liquid cuffs" experience along with the "Junkie" habitus effectively challenge disciplinary biopower. Loosening program regulations may improve quality of services and reduce harm. © 2014 Informa UK Ltd. Source

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