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Badagry, Nigeria

The Lagos State University - also known as LASU - was established in 1983 by the enabling Law of Lagos State of Nigeria, for the advancement of learning and establishment of academic excellence. The university caters for a population of over 61,000, enrolled in full-time and part-time programmes at the Diploma, Undergraduate and Postgraduate. Lagos State University , located in the city of Ojo, Lagos, Nigeria, is the only state university in the former British colony.The Vice-Chancellor is Professor John Oladapo Obafunwa.Lagos State University offers diploma, degree and post graduate programmes and its MBA programme is reputed to be one of the highly revered in the country. The citadel is also known for various staff union agitations especially the Lecturers' ASUU,non teching staff's SSANU,NASU and others while various unrest has been witnessed with the activities of the students union informally called LASUSU also known as the Lagos State University Student Union.The state university which is known as the best state owned university in Nigeria also boost of a robust academic staff which include highly respected political science scholar-Professor Abubakar Momoh, thespian- Dr. Sola Fosudo, actor-Doyin Hassan amongst others. Wikipedia.

Ogbera A.O.,Lagos State University
Diabetology and Metabolic Syndrome | Year: 2010

Background. The Metabolic syndrome (MetS) is a cardiovascular risk factor of public health significance and of recent has become a topical issue. The prevalence of diabetes mellitus (DM) is on the increase and with this scenario, a possible increase in burden of DM which may be largely attributed to cardiovascular complications is expected. The objective of this report is to determine the prevalence of the MetS and compare gender characteristics in subjects with type 2 DM. Methods. Subjects with type 2 DM were recruited from an urban hospital for the study. Clinical data was obtained by interviewing the patients and referring to their Case folders. The anthropometric indices and blood pressure measurements were documented. Laboratory parameters analysed for included total cholesterol, high density and low density cholesterol, triglyceride and glycosylated haemoglobin. Statistical analysis included usage of Student's t test and chi square. Results. 963 patients with type 2 DM aged between 35-85 years were recruited for the study. The main outcome measures included the prevalence of the metabolic syndrome and the gender differences of its components. The prevalence of the metabolic syndrome was 86%. The frequency of occurrence of the MetS was similar for men (83%) and women (86%) and increased with age in both sexes. The prevalence of MetS increased from 11% among participants aged 20 through 29 years to 89% in participants aged 70 through 79. In our patients with DM, the commonest occurring and least detected MetS defining parameters are central obesity and elevated triglyceride levels respectively. The components of the MetS that differed significantly in both sexes was HDL-C. The combination of the components of the MetS were comparable in both genders and 5.8% of the subjects with the MetS had all components of the MetS. Conclusion. The prevalence of the MetS in type 2DM is high in both genders and increases with age thus posing a potential high cardiovascular risk in this group of patients. The modifiable risk factors for the MetS should be a focus point in the management of subjects with type 2 DM,. © 2010 Ogbera; licensee BioMed Central Ltd.

Saalu L.C.,Lagos State University
Pakistan Journal of Biological Sciences | Year: 2010

The male factor is considered a major contributory factor to infertility. Apart from the conventional causes for male infertility such as varicocoele, cryptorchidism, infections, obstructive lesions, cystic fibrosis, trauma and tumours, a new and important cause has been identified as being responsible for the so-called idiopathic male infertility: oxidative stress. Oxidative Stress (OS) is a condition that occurs when the production of Reactive Oxygen Species (ROS) overwhelms the antioxidant defense produced against them. In male reproductive pathological conditions, the OS significantly impairs spermatogenesis and sperm function, which may lead to male infertility. Reactive Oxygen Species (ROS) known as free radicals are oxidizing agents generated as a result of metabolism of oxygen and have at least one unpaired electron that make them very reactive species. Spermatozoa generate Reactive Oxygen Species (ROS) in physiological amounts, which play a role in sperm functions during sperm capacitation, Acrosome Reaction (AR) and oocyte fusion, but they need to be controlled and their concentrations maintained at a level that is not deleterious to the cells. Administration of antioxidants in patients with 'male factor' infertility has begun to attract considerable interest. The main difficulty of such an approach is our incomplete understanding of the role of free radicals in normal and abnormal sperm function leading to male infertility. The purpose of the present review is to address the relationship between ROS and idiopathic male factor infertility. © 2010 Asian Network for Scientific Information.

Ajose F.O.A.,Lagos State University
International Journal of Dermatology | Year: 2012

Background African hair in its natural state poses tenacious grooming challenges; consequently a large portion of the African cosmetic industry is focused on means to relax the tight curls of African hair to make the hair more manageable. In malnourished and hypoproteinemic states, African hair straightens in an uncomplimentary manner. Recently, we observed that in certain diseases African hair changes to a desirable silky wavy texture. Method To identify the diseases that turn African hair silky and their parameters we examined 5612 dermatology patients at a tertiary hospital in Nigeria. We then studied the clinical and basic laboratory parameters of those patients whose diseases were accompanied by the silky hair change. Result Silky hair change similar to the hair of the African neonatal child was observed in five diseases, namely AIDS, rheumatoid arthritis, systemic lupus erythematosus, pulmonary tuberculosis with cachexia, and Behçet's disease. Conclusion Our study identified retrogression of African hair to the neonatal structure in five diseases. Anemia of chronic illness, high erythrocyte sedimentation rate, and mild hypocalcemia were significant laboratory parameters. This is an important observation, which should excite and advance research into the nature and structure of African hair. The causes of structural hair changes should include these five diseases. © 2012 The International Society of Dermatology.

Ogunleye O.O.,Lagos State University
African journal of medicine and medical sciences | Year: 2012

The clustering of cardiovascular risk factors and diseases has grievous implications on overall morbidity and mortality. There is however relative paucity of this information among the Nigerian population. This study was aimed at defining the prevalence of the clustering of hypertension (HT), diabetes mellitus (DM) and dyslipidemia (DYSL) in a Nigerian teaching hospital outpatient clinics population. A cross sectional study of patients managed at the hypertension and diabetes clinics of the Lagos State University Teaching Hospital, Nigeria between January and December 2008. The baseline demographic characteristics, blood pressures, blood sugars and fasting lipid profiles were obtained retrospectively from hospital records. Using the standard criteria for the diagnosis of HT, DM and DYSL, the prevalence of these conditions and their respective clusters were determined. A total of 506 patients were seen over this period, male; 234 (46.2%), female; 272(53.8%) with mean age of 57.35 (1.28) years. The prevalence of HT, DM and DYSL were 85%, 39.5% and 58.9% respectively. Concurrent HT and DYSL was the most prevalent cluster found in 146 patients (28.9%), followed by the clustering of the three co-morbidities of HT, DM and DYSL in 124 patients (24.5%).Other clusters were DM+HT; 49 (9.7%), DM+DYSL;13 (2.6%). 41.2% of the population had the clustering of at least two co-morbidities and about a quarter had the three conditions coexisting. There is a significant burden of the cardiovascular risk factors occurring in clusters in the Nigerian population studied. This calls for purposeful measures to control these risk factors.

Some physico-chemistry, nutrients and heavy metal content of Badagry Creek, Ologe Lagoon, Agbara and Ojo were compared to ascertain the effects of water hyacinth (Eichhornia crassipes) on these variables of the water bodies. Three of the water bodies (Ologe Lagoon, Agbara and Badagry Creek) have water hyacinth infestation and the control (Ojo) was free from water hyacinth through out the period of the study. This study was carried out between January, 2010 to August, 2010. Eleven physico-chemical parameters, 4 nutrients and 5 heavy metals were measured. The observed values shows that their was significant difference (p<0.05) in the conductivity, total dissolved solid, salinity, dissolved oxygen, Biological Oxygen Demand (BOD) and total hardness among the sampling stations. The highest values in conductivity (9272±994 μS cm -1), salinity (5.00±1.69 ppt), total hardness (1848±396 mg L -1) and Total dissolved solid (5460±841 mg L -1) were recorded in Ojo which has no water hyacinth infestation while the lowest values {conductivity (183±81 μS cm -1), salinity (0.11±0.01 ppt), total hardness (87±8 mg L -1) and total dissolved solid (92±15 mg L -1)} were obtained in Agbara which is one of the sampling stations with water hyacinth infestation. However, BOD was highest in Agbara (97.38±28.60 mg L -1) but lowest in Ojo (35.37±9.67 mg L -1). Sulphate and chloride were significant (p<0.05) among the sampling stations while magnesium was the only significant (p<0.05) heavy metal. Although, water hyacinth may have negative impacts on water quality, its ability to passively absorb heavy metals and nutrients can be put into good use. © 2012 Asian Network for Scientific Information.

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