Laboratory of Quality and Safety Risk Assessment for Livestock Product Lanzhou

Lanzhou, China

Laboratory of Quality and Safety Risk Assessment for Livestock Product Lanzhou

Lanzhou, China
SEARCH FILTERS
Time filter
Source Type

Xiong L.,Chinese Academy of Agricultural Sciences | Xiong L.,Laboratory of Quality and Safety Risk Assessment for Livestock Product Lanzhou | Huang L.,Lanzhou University | Shimo S.P.,Chinese Academy of Agricultural Sciences | And 7 more authors.
Chromatographia | Year: 2016

A high-performance liquid chromatography (HPLC) screening method with a photodiode array detector (PDAD) was established for the simultaneous determination of residues of 13 benzimidazoles (BZDs) and metabolites in sheep and cattle muscle and liver. Samples were extracted by ultrasonication in ethyl acetate and purified over DVB-NVP-SO3Na sorbent. Under the optimized conditions, good linearities were obtained for BZDs and metabolites with correlation coefficients (R2) greater than 0.9911. The recoveries of the 13 BZDs and metabolites from spiked samples were 72.0–119.3 %, with intraday and interday relative standard deviations (RSDs) below 22.8 %. The limits of detection (LODs) and quantitation (LOQs) were 0.8–4.9 and 2.6–18.2 μg kg−1, respectively. The results clearly demonstrated that the developed approach enables reliable screening of 12 BZDs and metabolites except flubendazole (FLU) and could be used as a regulatory tool for the screening of BZD and metabolite residues in the muscle and liver of sheep and cattle. © 2016 Springer-Verlag Berlin Heidelberg


Xiong L.,Chinese Academy of Agricultural Sciences | Xiong L.,Laboratory of Quality and Safety Risk Assessment for Livestock Product Lanzhou | Gao Y.-Q.,Chinese Academy of Agricultural Sciences | Gao Y.-Q.,Laboratory of Quality and Safety Risk Assessment for Livestock Product Lanzhou | And 6 more authors.
Meat Science | Year: 2015

A liquid chromatography with tandem mass spectrometric detection (LC-MS/MS) method was established for the simultaneous determination of the levels of 10 β2-agonists in meat. The samples were extracted using an aqueous acidic solution and cleaned up using a Quick, Easy, Cheap, Effective, Rugged and Safe (QuEChERS) technique utilising a DVB-NVP-SO3Na sorbent synthesised in-house. First, the β2-agonist residues were extracted in an aqueous acidic solution, followed by matrix solid-phase dispersion for clean-up. The linearities of the method were R2=0.9925-0.9998, with RSDs of 2.7-15.3% and 73.7-103.5% recoveries. Very low limits of detection (LOD) and quantitation (LOQ) of 0.2-0.9μg/kg and 0.8-3.2μg/kg, respectively, were achieved for spiked meat. The values obtained were lower than the maximum residue limits (MRLs) established by the EU and China. These results clearly demonstrate the feasibility of the proposed approach. The evaluated method provided reliable screening, quantification and identification of 10 β2-agonists in meat. © 2015 Elsevier Ltd.

Loading Laboratory of Quality and Safety Risk Assessment for Livestock Product Lanzhou collaborators
Loading Laboratory of Quality and Safety Risk Assessment for Livestock Product Lanzhou collaborators