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Zoccolillo L.,I.R.C.C.S. Fondazione Santa Lucia | Morelli D.,I.R.C.C.S. Fondazione Santa Lucia | Cincotti F.,Laboratory of Neuroelectrical Imaging | Muzzioli L.,Laboratory of Neuroelectrical Imaging | And 4 more authors.
European Journal of Physical and Rehabilitation Medicine | Year: 2015

Background. Previous studies reported controversial results about the efficacy of video-game based therapy (VGT) in improving neurorehabilitation outcomes in children with cerebral palsy (CP). Aim. Primary aim was to investigate the effectiveness of VGT with respect to conventional therapy (CT) in improving upper limb motor outcomes in a group of children with CP. Secondary aim was to quantify if VGT leads children to perform a higher number of movements. Design. A cross-over randomized controlled trial (RCT) for investigating the primary aim and a crosssectional study for investigating the secondary aim of this study. Settings. Outpatients. Population. Inclusion criteria: clinical diagnosis of CP, age between 4 and 14 years, level of GMFC between I and IV. Exclusion criteria: QI<35, severe comorbidities, incapacity to stand even with an external support. Methods. Twenty-two children with CP (6.89±1.91- year old) were enrolled in a cross-over RCT with 16 sessions of VGT (using Xbox with Kinect device) and then 16 of CT or vice versa. Upper limb functioning was assessed using the Quality of Upper Extremities Skills Test (QUEST) and hand abilities using Abilhandkids score. According to the secondary aim of this study a secondary cross-sectional study has been performed. Eight children with CP (6.50±1.60-year old) were enrolled into a trial in which five wireless triaxial accelerometers were positioned on their forearms, legs and trunk for quantifying the physical activity during VGT vs. CT. Results. QUEST scores significantly improved only after VGT (P=0.003), and not after CT (P=0.056). The reverse occurred for Abilhand-kids scores (P=0.165 vs. P=0.013, respectively). Quantity of performed movements was three times higher in VGT than in CT (+198%, P=0.027). Conclusion. VGT resulted effective in improving the motor functions of upper limb extremities in children with CP, conceivably for the increased quantity of limb movements, but failed in improving the manual abilities for performing activities of daily living which benefited more from CT. Clinical Rehabilitation Impact. VGT performed using the X-Box with Kinect device could enhance the number of upper limb movements in children with CP during rehabilitation and in turn improving upper limb motor skills, but CT remained superior for improving performances in manual activities of daily living.

Mak J.N.,New York State Department of Health | Arbel Y.,University of South Florida | Minett J.W.,Chinese University of Hong Kong | McCane L.M.,New York State Department of Health | And 5 more authors.
Journal of Neural Engineering | Year: 2011

This paper summarizes the presentations and discussions at a workshop held during the Fourth International BCI Meeting charged with reviewing and evaluating the current state, limitations and future development of P300-based brain-computer interface (P300-BCI) systems. We reviewed such issues as potential users, recording methods, stimulus presentation paradigms, feature extraction and classification algorithms, and applications. A summary of the discussions and the panel's recommendations for each of these aspects are presented. © 2011 IOP Publishing Ltd.

Vecchiato G.,University of Rome La Sapienza | Astolfi L.,University of Rome La Sapienza | Astolfi L.,Laboratory of Neuroelectrical Imaging | Tabarrini A.,Laboratory of Neuroelectrical Imaging | And 10 more authors.
Computational Intelligence and Neuroscience | Year: 2010

The use of modern brain imaging techniques could be useful to understand what brain areas are involved in the observation of video clips related to commercial advertising, as well as for the support of political campaigns, and also the areas of Public Service Announcements (PSAs). In this paper we describe the capability of tracking brain activity during the observation of commercials, political spots, and PSAs with advanced high-resolution EEG statistical techniques in time and frequency domains in a group of normal subjects. We analyzed the statistically significant cortical spectral power activity in different frequency bands during the observation of a commercial video clip related to the use of a beer in a group of 13 normal subjects. In addition, a TV speech of the Prime Minister of Italy was analyzed in two groups of swing and supporter voters. Results suggested that the cortical activity during the observation of commercial spots could vary consistently across the spot. This fact suggest the possibility to remove the parts of the spot that are not particularly attractive by using those cerebral indexes. The cortical activity during the observation of the political speech indicated a major cortical activity in the supporters group when compared to the swing voters. In this case, it is possible to conclude that the communication proposed has failed to raise attention or interest on swing voters. In conclusions, high-resolution EEG statistical techniques have been proved to able to generate useful insights about the particular fruition of TV messages, related to both commercial as well as political fields. Copyright © 2010 Giovanni Vecchiato et al.

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