Ejido Plan de Ayala, Mexico
Ejido Plan de Ayala, Mexico

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Cano-Europa E.,Laboratory Of Neurobiologia | Ortiz-Butron R.,Laboratory Of Neurobiologia | Blas-Valdivia V.,Laboratory Of Neurobiologia | Pineda-Reynoso M.,Laboratory Of Neurobiologia | And 2 more authors.
Journal of Applied Phycology | Year: 2010

Our objective was to study if the phycobiliproteins of the cyanobacterium Pseudanabanea tenuis rich in phycoerythrin protect renal cells against mercury-caused oxidative stress and cellular damage in the kidney. We used 40 male mice that were assigned into five groups: a control group that received phosphate buffer (PB) and saline and four treatment groups which received either PB+HgCl2, PB+phycobiliproteins, or HgCl2+phycobiliproteins. The kidneys of the mice were used to determine lipid peroxidation and quantification of reactive oxygen species, oxidized glutathione, and peroxidase activities (catalase and glutathione peroxidase) and were also examined histologically. Our results demonstrated that HgCl2 causes oxidative stress and cellular damage and that all doses of phycobiliproteins prevented the increase of oxidative markers and partially protected against HgCl2-caused cell damage. This is the first report which applied phycobiliproteins of P. tenuis rich in c-phycoerythrin, like antioxidants against mercury chloride-caused oxidative stress and renal damage. © 2009 Springer Science+Business Media B.V.


Blas-Valdivia V.,Laboratory Of Neurobiologia | Ortiz-Butron R.,Laboratory Of Neurobiologia | Pineda-Reynoso M.,Laboratory Of Neurobiologia | Hernandez-Garcia A.,Laboratory Of Neurobiologia | Cano-Europa E.,Laboratory Of Neurobiologia
Journal of Applied Phycology | Year: 2011

Chlorella vulgaris is a unicellular green alga resistant to heavy metals. Chlorella is a rich nutritional ingredient because it contains high levels of antioxidants. The objective of this research was to study if C. vulgaris protect renal cells against mercury-chloride-caused oxidative stress and cellular damage in the kidney. Our results demonstrated that HgCl2 causes oxidative stress and cellular damage, and that C. vulgaris administration prevents oxidative stress and cellular damage in kidney © 2010 Springer Science+Business Media B.V.

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