Santos S.M.,Federal University of Pernambuco |
Santos S.M.,Laboratorio Of Pericia E Pesquisa Em Genetica Forense Da Gerencia Geral Of Policia Cientifica Da Secretaria Of Defesa Social Of Pernambuco |
Souza C.A.,Laboratorio Of Pericia E Pesquisa Em Genetica Forense Da Gerencia Geral Of Policia Cientifica Da Secretaria Of Defesa Social Of Pernambuco |
Rabelo K.C.N.,Federal University of Pernambuco |
And 6 more authors.
Genetics and Molecular Research
Pernambuco is one of the 27 federal units of Brazil, ranking seventh in the number of inhabitants. We examined the allele frequencies of 13 short tandem repeat loci (CFS1PO, D3S1358, D5S818, D7S820, D8S1179, D13S317, D16S539, D18S51, D21S11, FGA, TH01, vWA, and TPOX), the minimum recommended by the Federal Bureau of Investigation and commonly used in forensic genetics laboratories in Brazil, in a sample of 609 unrelated individuals from all geographic regions of Pernambuco. The allele frequencies ranged from 5 to 47.2%. No significant differences for any loci analyzed were observed compared with other publications in other various regions of Brazil. Most of themarkers observed were in Hardy-Weinberg equilibrium. The occurrence of the allele 47.2 (locus FGA) and alleles 35.1 and 39 (locus D21S11), also described in a single study of the Brazilian population, was observed. The other forensic parameters analyzed (matching probability, power of discrimination, polymorphic information content, paternity exclusion, complement factor I, observed heterozygosity, expected heterozygosity) indicated that the studied markers are very informative for human forensic identification purposes in the Pernambuco population. © FUNPEC-RP. Source