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Cutro A.C.,Laboratorio Of Biointerfases Y Sistemas Biomimeticos | Hollmann A.,Laboratorio Of Biointerfases Y Sistemas Biomimeticos | Cejas J.,Laboratorio Of Biointerfases Y Sistemas Biomimeticos | Maturana P.,Laboratorio Of Biointerfases Y Sistemas Biomimeticos | And 2 more authors.
Colloids and Surfaces B: Biointerfaces | Year: 2015

The influence of Phe on the surface pressure of 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) monolayers at the air-water interface was studied at different initial surface pressures (26 and 40. mN/m) and two pHs (5.0 and 7.3) at constant temperature (20. °C). Changes produced by the aminoacid added to the subphase on the surface pressure and on the dipole potential of lipid monolayers were measured at a fixed area. Compressibility properties of the monolayers at different pHs were studied by (π-A) isotherms. The results suggest that Phe intercalates into a DPPC film at the air-water interface at pH 5 and forms a different arrangement at pH 7.3.The possible relevance of these results of the effect of Phe in physiological conditions is discussed. © 2015 Elsevier B.V.

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