Time filter

Source Type

Lagunes I.,University of Xalapas | Trigos A.,Laboratorio Of Alta Tecnologia Of Xalapa Latex | Trigos A.,University of Xalapas
Journal of Photochemistry and Photobiology B: Biology | Year: 2015

Consumption of antioxidant supplements is associated to prevention of several diseases. However, recent studies suggest that antioxidants, besides scavenge free radicals could lead development of tumors. Due to conflicting reports on the antioxidant benefits, the capacity to photosensitize the generation of singlet oxygen of seven natural antioxidants was evaluated through photo-oxidation of ergosterol which proved to be an efficient method of indirect detection of singlet oxygen. Our results showed that curcumin, resveratrol and quercetin have pro-oxidant activity due they act as photosensitizers in generation of singlet oxygen. In addition, we observed that genistein, naringenin, β-carotene and gallic acid besides their antioxidant activity against ROS radicals, are capable of quenching ROS non-radicals as singlet oxygen. Finally, our results allow us to propose a new approach in classification of natural antioxidants scavengers of free radicals, based on their activity as quenchers of singlet oxygen or as photosensitizers in singlet oxygen generation. © 2015 Published by Elsevier B.V.

Loading Laboratorio Of Alta Tecnologia Of Xalapa Latex collaborators
Loading Laboratorio Of Alta Tecnologia Of Xalapa Latex collaborators