Laboratoire Of Synthese Organique Par Voie Organometallique

Tunis, Tunisia

Laboratoire Of Synthese Organique Par Voie Organometallique

Tunis, Tunisia
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Kaabi A.,Laboratoire Of Synthese Organique Par Voie Organometallique | Elemine B.O.,Laboratoire Of Synthese Organique Par Voie Organometallique | Besbes R.,Laboratoire Of Synthese Organique Par Voie Organometallique
Synthetic Communications | Year: 2011

A series of new trans-N-alkylaziridine-2-carboxylates 3 was conveniently synthesized in a one-pot reaction by treatment of 1,2-amino alcohol mono and diesters 1 with methanesulfonyl chloride in the presence of (iPr) 2NEt. The products were obtained in good to excellent yields with high trans-selectivity. © 2011 Taylor and Francis Group, LLC.


Elemine B.O.,Laboratoire Of Synthese Organique Par Voie Organometallique | Besbes R.,Laboratoire Of Synthese Organique Par Voie Organometallique | Ennigrou M.R.,Laboratoire Of Synthese Organique Par Voie Organometallique
Synthetic Communications | Year: 2010

A variety of 1,2-amino alcohol diesters 1 reacted smoothly with diethyl chlorophosphate under basic conditions to afford the corresponding 1,2-amino phosphate diesters 2 in excellent yields. These compounds served as useful precursors for subsequent nucleophilic attack by alcohols in an SN2 fashion to provide 1,2-amino ether diesters 3. © 2009 Taylor & Francis Group, LLC.

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