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PubMed | Service de Biochimie Clinique, Laboratoire Of Recherche Immuno Rhumatologie and University of Sousse
Type: Journal Article | Journal: The Journal of sports medicine and physical fitness | Year: 2016

The present study was designed to examine the influence of extreme impact loading induced by jump training on bone mineral density (BMD) and bone mineral content (BMC) in high level jumpers.Forty boys volunteered for the study aged 20 to 21 years. They were 22 high level jumpers and 18 controls. Bone mass and body composition measurements were performed by dual-energy X-ray absorptiometry, in the total body and at different sites.The results showed that BMC, BMD, bone area, and lean mass (P<0.0001) were significantly higher in the jumpers compared to the controls. A strong positive correlation was found between lean mass and bone parameters (BMC at the right femur, r=0.80; P<0.01). The values of the same correlation were weak in the control group. In addition, the effects of the regular practice of jumping on the BMD, BMC, and bone area were more pronounced in the lower limbs (P<0.01). These adaptations were site-specific, with increased bone mass at the lower limbs (P<0.01), especially at the legs, right and left leg (LRL) (P<0.05). It appears that the time dedicated to this activity may be account for the difference between jumpers and controls.The practice of high level jump starting at pubertal age generates an increase and an acquisition of the bone mass in males. This adaptation is further enhanced by the times dedicated for this activity. Therefore, it would be interesting to program jumping activities daily to conserve bone mineral and to prevent osteopenia.


Kalai E.,Service de Biochimie | Bahlous A.,Service de Biochimie | Bouzid K.,Service de Biochimie | Laadhar L.,Laboratoire Of Recherche Immuno Rhumatologie | And 5 more authors.
Annales de Biologie Clinique | Year: 2014

Aims: To investigate the association between type II collagen fragments and the presence of knee osteoarthritis (OA) in the Tunisian population and to determine whether this biomarker can predict X-ray progression of this disease. Methods: Type II collagen C-telopeptide (uCTX-II) and helical peptide (sHelix-II) were assessed in 125 female patients with knee osteoarthritis aged 54 ± 8 years over 2 years and 57 female age-matched controls. The markers were measured at baseline, 1 and 2 yrs' follow-up corresponding to x-ray time points. Results: Only urinary CTX-II values were significantly 48% higher in knee OA patients compared with controls (p=0.001). The longitudinal changes over 2 yrs in Helix-II were also significantly associated with Joint Space Narrowing: JSN (p=0.03). Over the 2-yr study period average CTX-II levels were not significantly higher in progressor compared with non-progressor (339.96 vs 256.00; NS). Conclusion: The data presented here suggest that CTX-II may be useful to identify patients with knee OA. These results demonstrate significantly association between progression of this disease and alterations levels of Helix-II.


PubMed | Service de biochimie and Laboratoire Of Recherche Immuno Rhumatologie
Type: Journal Article | Journal: Annales de biologie clinique | Year: 2014

To investigate the association between type II collagen fragments and the presence of knee osteoarthritis (OA) in the Tunisian population and to determine whether this biomarker can predict X-ray progression of this disease.Type II collagen C-telopeptide (uCTX-II) and helical peptide (sHelix-II) were assessed in 125 female patients with knee osteoarthritis aged 54 8 years over 2 years and 57 female age-matched controls. The markers were measured at baseline, 1 and 2 yrs follow-up corresponding to x-ray time points.Only urinary CTX-II values were significantly 48% higher in knee OA patients compared with controls (p=0.001). The longitudinal changes over 2 yrs in Helix-II were also significantly associated with Joint Space Narrowing: JSN (p=0.03). Over the 2-yr study period average CTX-II levels were not significantly higher in progressor compared with non-progressor (339.96 vs 256.00; NS).The data presented here suggest that CTX-II may be useful to identify patients with knee OA. These results demonstrate significantly association between progression of this disease and alterations levels of Helix-II.

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