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Poirel L.,University Paris - Sud | Nordmann P.,University Paris - Sud | Ducroz S.,University Paris - Sud | Boulouis H.-J.,Laboratoire Of Bacteriologie Lcaast | And 2 more authors.
Antimicrobial Agents and Chemotherapy | Year: 2013

Screening of extended-spectrum αlactamase (ESBL)-producing Gram-negative bacteria in companion animals living in the Paris area in France identified a high rate of CTX-M-15-producing Klebsiella pneumoniae. Those isolates were recovered during the 2010-2011 period from both infections and asymptomatic colonizations. Sequence typing revealed that most of these isolates belonged to sequence type ST274. Interestingly, the blaCTX-M-15 gene was located on a specific and novel plasmid scaffold. These findings highlight that companion animals may be reservoirs for CTX-M-15-producing K. pneumoniae evolving separately from the human reservoir of CTX-M-15 producers. Copyright © 2013, American Society for Microbiology. All Rights Reserved.

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