Kyoto University , or Kyodai is a national university located in Kyoto, Japan. It is the second oldest Japanese university, one of the highest ranked universities in Asia and one of Japan's National Seven Universities. One of Asia’s leading research-oriented institutions, Kyoto University is famed for producing world-class researchers, including ten Nobel Prize laureates, two Fields medalists and one Gauss Prize. Wikipedia.
Kyoto University | Date: 2017-04-26
In an information terminal processing device 1 of a first user, after selection of a content on a prescribed experience by the first user, content identification information is output to an information terminal device 3 of a second user B, and various information thereof is transmitted to a server device 3. In an information terminal device 2 of a second user B, after the content identification information is input, a unique key corresponding to the content identification information is generated, information on the input date and time and/or the input location of the content identification information is transmitted to the server device 3. In the server device 3, after collating unique keys, the input date and time and/or the input location of the content identification information are defined as a shared date and time and/or a shared location of the content, and the shared experience information is constructed to make a database thereof.
Nihon Medi Physics Co., Kyoto University and National Hospital Organization | Date: 2017-05-03
Provided is a compound represented by general formula (1) or a salt thereof as well as a medicine containing the compound or the salt. (In the formula, R_(1) represents a hydrogen atom or CO_(2)R_(a); R_(2) represents a hydrogen atom, a halogen atom, or CO_(2)R_(a); R_(3) represents a hydrogen atom or a C1-10 hydroxyalkyl group; R_(4) represents a hydrogen atom, a hydroxy group, or a C1-10 alkoxy group; R_(5) represents a C1-5 chain alkyl group in which the hydrogen atoms are optionally substituted with halogen atoms, a C3-5 cyclic alkyl group in which the hydrogen atoms are optionally substituted with halogen atoms, a C1-5 hydroxyalkyl group, or an o-, p-, or m-halobenzyl group; A represents CH or a nitrogen atom; X_(1) and X_(3) independently represent hydrogen atoms or halogen atoms; X_(2) represents a hydrogen atom, a halogen atom, or a nitrile group; at least one of X_(1), X_(2), and X_(3) represents a halogen atom; and R_(a) independently represents a C1-10 alkyl group.)
Kyoto University | Date: 2017-05-17
The present invention relates to a method for determining prognosis of cancer in a subject, which comprises the step of detecting phosphorylation of a tyrosine residue at position 2681 of TRIO in a sample obtained from the subject.
Kyoto University and Thyas Co. | Date: 2017-05-24
Provided is a method for inducing T cells for a cell-based immunotherapy, comprising the steps of:(1) providing Rag 1 and/or Rag2 gene knockout human pluripotent stem cells bearing genes encoding a T cell receptor specific for a desired antigen, and(2) inducing T cells from the pluripotent stem cells of step (1). Further provided are a cell-based immunotherapy method that uses the T cells for the cell-based immunotherapy and an iPS cell bank for the cell-based immunotherapy.
Kyoto University | Date: 2017-05-24
A method for extracting differentiated cells from a cell population comprising undifferentiated cells after induction of the differentiation of pluripotent stem cells. A method for extracting differentiated cells from a cell population, comprising the following steps: (1) a step of introducing, into a cell population, mRNA comprising a marker gene operably linked to the target sequence of miRNA specifically expressed in pluripotent stem cells; and (2) a step of extracting cells in which the marker gene has been translated.
Nissan Chemical Industries Ltd. and Kyoto University | Date: 2017-03-02
The present invention provides a culture method of cells and/or tissues including culturing cells and/or tissues in a suspended state by using a medium composition wherein indeterminate structures are formed in a liquid medium, the structures are uniformly dispersed in the solution and substantially retain the cells and/or tissues without substantially increasing the viscosity of the solution, thus affording an effect of preventing sedimentation thereof, and the like
Ajinomoto Co. and Kyoto University | Date: 2017-06-28
The problem of the present invention is to provide a means that enables conventionally-difficult growth and culture of mesenchymal stem cells for a long period, without using any special apparatus, equipment and the like. The above problem is solved by providing a medium for mesenchymal stem cells in which seven kinds of nonessential amino acids of glycine, alanine, serine, proline, asparagine, aspartic acid and glutamic acid are reduced.
Kyoto University and Godo Shigen Co. | Date: 2017-07-12
A living radical polymerization initiator represented by the following general formula (1), which uses a living radical polymerization initiator that contains, as initiating groups for reactions, two halogen atoms different from each other in reactivity, and which enables different living radical polymerization reactions to proceed with respect to the respective initiating groups: herein, R^(1) represents an organic group which is linkable with two or more other organic groups, and which is selected from an aliphatic group having 1 to 12 carbon atoms, an aromatic group, a carbonyl group, a sulfonyl group and an organic group obtained by combining two or more of these groups, R^(2) , R^(3), R^(4) and R^(5) are a hydrogen atom or an organic group selected from an aliphatic group having 1 to 12 carbon atoms, an aromatic group, a carbonyl group, a carboxyl group and a sulfonyl group, X and Y are a halogen atom, m and n are an integer of 1 or more, and the X and Y are in a state in which they are different from each other in reactivity with a monomer.
Kyoto University, Oita University and Kyushu University | Date: 2017-07-19
The present invention provides an alloy fine particle including palladium and ruthenium, the alloy fine particle including at least one first phase in which the palladium is more abundant than the ruthenium and at least one second phase in which the ruthenium is more abundant than the palladium, the at least one first phase and the at least one second phase being separated by a phase boundary, the palladium and the ruthenium being distributed in the phase boundary in such a manner that the molar ratio of the palladium and the ruthenium continually changes, a plurality of crystalline structures being present together in the phase boundary.
National Cancer Center Research Institute, Kyoto University and Otsuka Pharmaceutical Factory Inc. | Date: 2017-08-02
A method for evaluating an efficacy of a chemoradiotherapy against squamous cell carcinoma comprises the following steps (a) to (c):(a) detecting an expression level of at least one gene selected from a SIM2 gene and genes co-expressed with the SIM2 gene in a squamous cell carcinoma specimen isolated from a subject;(b) comparing the expression level detected in the step (a) with a reference expression level of the corresponding gene; and(c) determining that an efficacy of a chemoradiotherapy against squamous cell carcinoma in the subject is high if the expression level in the subject is higher than the reference expression level as a result of the comparison in the step (b).