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Kyoto, Japan

Kyoto Sangyo University is a private university in Kita-ku, Kyoto, Kyoto, Japan. Wikipedia.

Araki K.,Kyoto Sangyo University | Inaba K.,Kyushu University
Antioxidants and Redox Signaling

Significance: Disulfide bond formation is an essential reaction involved in the folding and maturation of many secreted and membrane proteins. Both prokaryotic and eukaryotic cells utilize various disulfide oxidoreductases and redox-active cofactors to accelerate this oxidative reaction, and higher eukaryotes have diversified and refined these disulfide-introducing cascades over the course of evolution. Recent Advances: In the past decade, atomic resolution structures have been solved for an increasing number of disulfide oxidoreductases, thereby revealing the structural and mechanistic basis of cellular disulfide bond formation systems. Critical Issues: In this review, we focus on the evolution, structure, and regulatory mechanisms of endoplasmic reticulum oxidoreductin 1 (Ero1) family enzymes, the primary disulfide bond-generating catalysts in the endoplasmic reticulum (ER). Detailed comparison of Ero1 with other oxidoreductases, such as Prx4, QSOX, Erv1/2, and disulfide bond protein B (DsbB), provides important insight into how this ER-resident flavoenzyme acts in a regulated and specific manner to maintain redox and protein homeostasis in eukaryotic cells. Future Directions: Currently, it is presumed that multiple pathways in addition to that mediated by Ero1 cooperate to achieve oxidative folding of many secretory and membrane proteins in mammalian cells. The important open question is how each oxidative pathway works distinctly or redundantly in response to various cellular conditions. Antioxid. Redox Signal. 16, 790-799. © Copyright 2012, Mary Ann Liebert, Inc. 2012. Source

Umetsu K.,Kyoto Sangyo University
Physics Letters, Section B: Nuclear, Elementary Particle and High-Energy Physics

It is shown that the derivation of the Hawking radiation from a rotating black hole on the basis of the tunneling mechanism is greatly simplified by using the technique of the dimensional reduction near the horizon. This technique is illustrated for the original derivation by Parikh and Wilczek, but it is readily applied to a variant of the method such as suggested by Banerjee and Majhi. © 2010. Source

Matsuzaki S.,Kyoto Sangyo University | Yamawaki K.,Nagoya University
Physics Letters, Section B: Nuclear, Elementary Particle and High-Energy Physics

A new particle at around 125 GeV has been observed at the LHC, which we show could be identified with the techni-dilaton (TD) predicted in the walking technicolor and thus should be an evidence of walking technicolor. The TD is a pseudo Nambu-Goldstone boson for the approximate scale symmetry spontaneously broken by techni-fermion condensation, with its lightness being ensured by the approximate scale invariance of the walking technicolor. We test the goodness-of-fit of the TD signatures using the presently available LHC data set, and show that the 125 GeV TD is actually favored by the current data to explain the reported signal strengths in the global fit as well as in each channel including the coupling properties, most notably the somewhat large diphoton event rate. © 2013 Elsevier B.V. Source

Yamashita T.,Kyoto Sangyo University
Physical Review D - Particles, Fields, Gravitation and Cosmology

We present a new solution to the doublet-triplet splitting problem which also works in a supersymmetric SU(5) grand unified theory and is testable at TeV-scale collider experiments. In our model, the SU(5) symmetry is broken through the Hosotani mechanism. Thanks to the phase nature of the Hosotani breaking, the "missing VEV" can be realized even in an SU(5) model. A general and distinctive prediction of this solution is the existence of light adjoint chiral supermultiplets with masses of the supersymmetry-breaking scale. Though these fields disturb the gauge coupling unification, it can be recovered, keeping the unified gauge coupling constant perturbative, by introducing additional vectorlike particles, which may be also observed in the upcoming collider experiments. © 2011 American Physical Society. Source

Hotta C.,Kyoto Sangyo University
Physical Review B - Condensed Matter and Materials Physics

We study ground-state properties of a one-dimensional quarter-filled strongly correlated electronic chain coupled to an antiferromagnetic Ising chain by the density-matrix renormalization-group method. We focus on the case where large Coulomb interactions localize the charges on every other site. Both the electronic spins and the Ising moments interact antiferromagnetically within each chain. Since the number of electrons is half as that of Ising moments, the two intrachain Néel orders are incompatible and compete with each other. When the Ising chain is ordered (gapped), the electrons are magnetically frustrated, which is reflected in the nearly degenerate energy levels with different magnetization. The resultant magnetoelectric effect is elucidated as a suppression of a charge gap by the magnetic field. © 2010 The American Physical Society. Source

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