Kyoto Prefectural University

www.kpu.ac.jp/
Kyoto, Japan

Kyoto Prefectural University , Fudai or Kyōfudai for short, is one of the public universities in Japan. Its campus is located in Nakaragi-cho, Shimogamo, Sakyo-ku, Kyoto. Wikipedia.

SEARCH FILTERS
Time filter
Source Type

Patent
Kyoto Prefectural University | Date: 2017-07-26

The present invention addresses the problem of providing a method for obtaining Schwann cells directly (by direct reprogramming) without passing through pluripotent stem cells, such as ES cells or iPS cells. As a means for solving this problem, the present invention provides a method for preparing Schwann cells that includes a step of introducing into somatic cells of a mammal at least one gene selected from the group consisting of SOX10 genes and KROX20 genes, or an expression product thereof.


Patent
Kyoto Prefectural University, The Doshisha and Senju Pharmaceutical Co. | Date: 2017-09-06

The present invention provides a technique for treating retinal epithelium and/or nerves. More specifically, the present invention is an agent for the treatment or prevention of retinal disease or the like and/or a disease, disorder, or ophthalmological state of the nerves, the agent including at least one factor selected from the group consisting of laminin and fragments thereof, wherein the problem is solved by also providing a technique characterized in that this agent is administered together with retinal pigment epithelial cells and/or nerve cells. Specifically, the present invention can include laminin 411 (411), laminin 511 (511), laminin 521 (521), or fragments of these.


Patent
Kyoto Prefectural University, The Doshisha and Senju Pharmaceutical Co. | Date: 2017-09-06

The present invention provides a technique for treating the cornea. More specifically, the present invention is an agent for the treatment or prevention of a state of corneal endothelial disease, the agent including at least one factor selected from the group consisting of laminin and fragments thereof, wherein the problem is solved by also providing a technique characterized in that this agent is administered together with corneal endothelial cells. Specifically, the present invention can include laminin 511 (511), laminin 521 (521), or a fragment of these.


Patent
Kyoto Prefectural University, The Doshisha and Senju Pharmaceutical Co. | Date: 2017-02-27

The present invention relates to a differentiation marker and a differentiation controlling technique for an eye cell. More particularly, the present invention has attained an object of providing a differentiation marker for an eye cell among the aforementioned problems, by providing a marker for identifying a cell having a high proliferation ability among corneal endothelial cells and/or the differentiation ability of a corneal endothelial cell, the marker comprising GPR49/LGR5, as well as a detection agent or detection method for identifying a cell having a high proliferation ability among corneal endothelial cells and/or the differentiation ability of a corneal endothelial cell, comprising a substance binding to GPR49/LGR5. In addition, the present invention has attained an object of providing a differentiation controlling technique for an eye cell, by providing an agent for suppressing differentiation and/or promoting proliferation of an eye cell, comprising R-spondins.


Patent
Kyoto Prefectural University | Date: 2017-02-22

An object of the present invention is to provide a method for preparing osteoblasts that are applicable, without causing risk of canceration, to bone defect repair or to the treatment of bone resorption, fracture, osteoporosis, or the like. To solve this problem, the present invention provides a method for preparing osteoblasts, the method comprising culturing mammal differentiated somatic cells in a medium in the presence of at least one compound selected from the group consisting of (1) statin compounds, (2) casein kinase 1 inhibitors, (3) cAMP inducers, and (4) histone methyltransferase inhibitors, to convert the somatic cells into osteoblasts.


Patent
Kyoto Prefectural University | Date: 2015-04-17

An object of the present invention is to provide a method for preparing osteoblasts that are applicable, without causing risk of canceration, to bone defect repair or to the treatment of bone resorption, fracture, osteoporosis, or the like. To solve this problem, the present invention provides a method for preparing osteoblasts, the method comprising culturing mammal differentiated somatic cells in a medium in the presence of at least one compound selected from the group consisting of (1) statin compounds, (2) casein kinase 1 inhibitors, (3) cAMP inducers, and (4) histone methyltransferase inhibitors, to convert the somatic cells into osteoblasts.


Patent
Kyoto Prefectural University and Meiji Seika Pharma Co. | Date: 2017-06-14

A novel plant growth-promoting agent and a plant growth-promoting method using the same are provided. The plant growth-promoting agent contains a lactic acid bacterium having a plant growth-promoting action. Also, in the plant growth-promoting method, a seed, a plant body and/or a soil is treated with a lactic acid bacterium having a plant growth-promoting action. Lactobacillus plantarum strain FERM BP-21501 is suitable as the lactic acid bacterium having a plant growth-promoting action.


Patent
Kyoto University, ARKRAY Inc. and Kyoto Prefectural University | Date: 2016-04-13

A method for forming an immune-tolerant site, and a method for attracting immunosuppressive cells, comprising contacting an agent comprising SEK-1005 (Ser, 3-hydroxy-N-[2-hydroxy-1-oxo-2-tetrahydro-2-hydroxy-6-methyl-5-(2-methylpropyl)-2H-pyran-2-yl-propyl]-Leu-Pip(hexahydro-3-pyridazinecarbonyl)-N-hydroxy-Ala-N-methyl-Phe-Pip-rho-lactone) and/or fibroblast growth factor (FGF) with a site in the body tissue.


Patent
Kyoto University, ARKRAY Inc. and Kyoto Prefectural University | Date: 2016-10-19

An agent for forming an immune-tolerant site, and an agent for attracting immunosuppressive cells, comprising an agent comprising SEK-1005 (Ser, 3-hydroxy-N-[2-hydroxy-1-oxo-2-tetrahydro-2-hydroxy-6-methyl-5-(2-methylpropyl)-2H-pyran-2-yl-propyl]-Leu-Pip(hexahydro-3-pyridazinecarbonyl)-N-hydroxy-Ala-N-methyl-Phe-Pip-rho-lactone) and/or fibroblast growth factor (FGF).


Patent
Nagase Medicals Co. and Kyoto Prefectural University | Date: 2016-08-10

The present invention relates to a cleaner for an endoscope, the cleaner being used inside a living body during an endoscopic surgical procedure. In particular, an object of the present invention is to reduce the burden on a physician and the patient during an endoscopic surgical procedure. The present invention therefore relates to a cleaner for cleaning debris from an endoscope and/or endoscopic accessories, such as an endoscope lens and/or an endoscope hood (attachment), inside a living body. The present invention also relates to an antifoulant for antifouling treatment of an endoscope and/or endoscopic accessories. The antifoulant may comprise, for example, (i) a nonionic surfactant with an HLB of 1 to 11 and (ii) a nonionic surfactant with an HLB of 11 to 20.

Loading Kyoto Prefectural University collaborators
Loading Kyoto Prefectural University collaborators