Kurt Kitzing Co.

Wallerstein, Germany

Kurt Kitzing Co.

Wallerstein, Germany
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Wanner J.,Kurt Kitzing Co | Jirovetz L.,University of Vienna | Schmidt E.,University of Vienna
Current Bioactive Compounds | Year: 2015

The essential oil of Callitris intratropica is composed to a considerable proportion of rather unique lactones like callitrin (I), callitrisin (II) and columellarin (III) (Fig. 1) 1-7.. During the investigation of the volatiles obtained by hydrodistillation of the wood of this Cupressaceae species 8. we noticed that the oil yield increases with distillation time while the oil composition is shifted more and more towards the high boiling components. To find the reason for this behavior some wood was extracted in a Soxhlet apparatus and the resulting red-brown resinous oil analyzed by GC-MS-FID on a short GC column. The lignans deoxypodorhizon (IV) and deoxypodophyllotoxin (V) 9 -11. were disclosed and present in rather large amounts. Since the wood is available in large quantities this finding points out a new rich source 12 - 14. of these potent bioactive lignans. © 2015 Bentham Science Publishers.


Schmidt E.,University of Vienna | Huong L.T.,Vinh University | Thang T.D.,Vinh University | Wanner J.,Kurt Kitzing Co. | Jirovetz L.,University of Vienna
Natural Product Communications | Year: 2016

The present study evaluates the chemical composition and olfactory description of the essential oils of Asarum glabrum Merr., Calocedrus macrolepis Kurz, Cunninghamia lanceolata (Lamb.) Hook. and Glyptostrobus pensilis (Stainton ex D.Don) K. Koch. The essential oils were obtained by hydrodistillation in a Clevenger-type apparatus and analyzed by GC-FID and GC-MS. Concerning their chemical composition, 66, 42, 57 and 21 volatile compounds were identified from dried leaves in the case of Asarum glabrum Merr. and wood for the other three, representing 98.7%, 67.2%, 92.0% and 87.5 % of the total composition, respectively. The main compounds of Asarum glabrum oil were safrole (38.1%), apiole (10.8%) and myristicin (8.0%); of Calocedrus macrolepis verbenone (9.3%), piperitone (8.6 %), α-terpineol (6.0%) and (Z)-β-terpineol (5.3%); of Cunninghamia lanceolata oil cedrol (26.3%), α-terpineol (24.1%) and camphor (7.0%); and of Glyptostrobus pensilis oil dihydro-eudesmol isomer (assumed) (18.3%), cedrol (16.4%), occidentalol (13.2%) and elemol (9.0%).


Stappen I.,University of Vienna | Hoelzl A.-S.,University of Vienna | Randjelovic O.,University of Vienna | Wanner J.,Kurt Kitzing Co
Natural Product Communications | Year: 2016

The influence of essential ginger oil (Zingiberis aetheroleum from Zingiber officinale Roscoe) on blood pressure, heart rate and subjective well-being was investigated after inhalation and dermal application on healthy human subjects in two experiments. Additionally a GC-MS analysis of the tested oil is given. The essential oil exhibited a high amount of citral (19.4%). α-Zingiberene (17.4%), camphene (7.8%), trans, trans-α-farnesene (6.8%) and β-bisabolene (5.8%) were also prominent constituents. Compared with the control condition an activating effect was observed for ginger oil in the inhalation experiment.


Abdelli W.,University of Mostaganem | Bahri F.,University of Mostaganem | Romane A.,Cadi Ayyad University | Hoferl M.,University of Vienna | And 3 more authors.
Natural Product Communications | Year: 2017

This work aims to elucidate the chemical composition of two essential oil (EO) samples obtained from the leaves of Thymus vulgaris L. (Lamiaceae) collected in two regions of Northwestern Algeria (Tlemcen and Mostaganem) and to assess their in vivo acute toxicity and anti-inflammatory activity. Sixty-six compounds could be identified by means of simultaneous GC-FID and GC-MS, accounting for 99.3% of total thyme oil of Mostaganem (EO.TM) and 99.0% of Tlemcen (EO.TT). In both samples, thymol was the major component, amounting to 59.5% (EO.TM) and 67.3% (EO.TT) of the total oil. EO.TT proved to be acutely toxic to mice at a dose of 4500 mg/kg p.o., whereas EO.TM did not show signs of acute toxicity, even at the highest dose tested (5000 mg/kg p.o.). Both EO samples were proven to possess anti-inflammatory activities, significantly reducing carrageenan-induced paw edema in mice (after 6 hours at a dose of 400 mg/kg p.o) at 58.4% for EO.TT and 50.4% for EO.TM, respectively. In conclusion, it could be demonstrated that EOs of T. vulgaris exhibit a considerable in vivo anti-inflammatory activity at non-toxic doses.


Schmidt E.,University of Vienna | Wanner J.,Kurt Kitzing Co. | Hoferl M.,University of Vienna | Jirovetz L.,University of Vienna | And 5 more authors.
Natural Product Communications | Year: 2012

The essential oils of four chemotypes of Thymus vulgaris L. (Lamiaceae) were analyzed for their composition and antibacterial activity to assess their different properties. GC-MS and GC-FID analyses revealed that the essentials oils can be classified into the chemotypes thymol (41.0% thymol), geraniol (26.4% geraniol), linalool (72.5% linalool) and 4-thujanol/terpinen-4-ol (42.2% cis- and 7.3% trans-sabinene hydrate, 6.5 % terpinen-4-ol). The olfactory examination confirmed the explicit differences between these chemotypes. Furthermore, antibacterial activity was investigated against several strains of two Gram-positive (Brochothrix thermosphacta and Staphylococcus aureus) and four Gram-negative food-borne bacteria (Escherichia coli, Salmonella abony, Pseudomonas aeruginosa and P. fragi). All essential oil samples were demonstrated to be highly effective against Gram-positive strains, whereas the impact on Gram-negative microorganisms was significantly smaller, but still considerable. The results obtained indicate that, despite their different properties, the essential oils of selected T. vulgaris chemotypes are potent antimicrobials to be employed as useful additives in food products as well as for therapeutic applications.


Wanner J.,Kurt Kitzing Co. | Bail S.,University of Vienna | Jirovetz L.,University of Vienna | Buchbauer G.,University of Vienna | And 5 more authors.
Natural Product Communications | Year: 2010

Cumin oil samples (Cuminum cyminum L.) from four different geographical origins were analyzed using GC-MS and GC-FID for their qualitative and quantitative composition. The major compounds in all cumin oils were the monoterpenes β-pinene, p-cymene and γ-terpinene and the terpenoid aldehydes cuminic aldehyde and the isomeric menthadien carboxaldehydes. All essential oils, and cuminic aldehyde, were tested, using agar diffusion and serial dilution methods, against different Gram-positive and Gram-negative bacteria isolated from different sources of food (pork fillet, minced meat and sausages) and clinical isolates, as well as three different Candida albicans isolates. All cumin oils and cuminic aldehyde exhibited a considerable inhibitory effect against all the organisms tested, except Pseudomonas spp.


Wanner J.,Kurt Kitzing Co. | Schmidt E.,Kurt Kitzing Co. | Bail S.,University of Vienna | Jirovetz L.,University of Vienna | And 5 more authors.
Natural Product Communications | Year: 2010

The chemical compositions of selected essential oils from North Africa, especially Morocco, of geranium, wild Moroccan chamomile and rosemary as well as absolutes of rose and geranium were determined using GC/FID and GC/MS. These oils and absolutes were tested concerning their antimicrobial activity against some food spoilage strains obtained from fresh milk and minced meat products, like sausages and pork fillet, in accordance with ISO testing procedures. Gram-positive (Bacillus cereus and Staphylococcus aureus) and Gram-negative (Escherichia coli, Salmonella abony and Pseudomonas aeruginosa) strains were used, as well as the yeast Candida albicans. Using a serial broth dilution method, all samples demonstrated weak antimicrobial activity against the Gram-negative bacteria and the yeast, compared with the activity towards the Gram-positive bacteria.


Wanner J.,Kurt Kitzing Co. | Schmidt E.,Gottfried Keller Strasse 8 | Bail S.,University of Vienna | Jirovetz L.,University of Vienna | And 5 more authors.
Natural Product Communications | Year: 2010

The chemical composition of essential oils of cabreuva (Myrocarpus fastigiatus Allemao, Fabaceae) from Brazil, cedarwood (Juniperus ashei, Cupressaceae) from Texas, Juniper berries (Juniperus communis L., Cupressaceae) and myrrh (Commiphora myrrha (Nees) Engl., Burseraceae) were analyzed using GC/FID and GC/MS. The antimicrobial activity of these essential oils and some of their main compounds were tested against eleven different strains of Gram-positive and Gram-negative bacteria by using agar diffusion and agar serial dilution methods. Animal and plant pathogens, food poisoning and spoilage bacteria were selected. The volatile oils exhibited considerable inhibitory effects against all tested organisms, except Pseudomonas, using both test methods. Higher activity was observed against Gram-positive strains in comparison with Gram-negative bacteria. Cabreuva oil from Brazil showed similar results, but in comparison with the other oils tested, only when higher concentrations of oil were used.


PubMed | Institute of Himalayan Bioresource Technology, CSIR - Central Electrochemical Research Institute, University of Vienna, University of Food Technologies and 3 more.
Type: Journal Article | Journal: Planta medica | Year: 2014

Artemisia species possess pharmacological properties that are used for medical purposes worldwide. In this paper, the essential oils from the aerial parts of Artemisia nilagirica and Artemisia maritima from the western Indian Himalaya region are described. The main compounds analyzed by simultaneous GC/MS and GC/FID were camphor and 1,8-cineole from A.maritima, and camphor and artemisia ketone from A.nilagirica. Additionally, the oils were evaluated for their antibacterial, antifungal, mosquito biting deterrent, and larvicidal activities. A.nilagirica essential oil demonstrated nonselective antifungal activity against plant pathogens Colletotrichum acutatum, Colletotrichum fragariae, and Colletotrichum gloeosporioides, whereas A.maritima did not show antifungal activity. Both Artemisia spp. exhibited considerable mosquito biting deterrence, whereas only A.nilagirica showed larvicidal activity against Aedes aegypti. Antibacterial effects assessed by an agar dilution assay demonstrated greater activity of A.maritima essential oil against Staphylococcus aureus and Pseudomonas aeruginosa compared to A.nilagirica.


PubMed | University of Vienna, Kurt Kitzing Co. and University of Food Technologies
Type: Journal Article | Journal: Antioxidants (Basel, Switzerland) | Year: 2016

The essential oil of juniper berries (Juniperus communis L., Cupressaceae) is traditionally used for medicinal and flavoring purposes. As elucidated by gas chromatography/flame ionization detector (GC/FID) and gas chromatography/mass spectrometry (GC/MS methods), the juniper berry oil from Bulgaria is largely comprised of monoterpene hydrocarbons such as -pinene (51.4%), myrcene (8.3%), sabinene (5.8%), limonene (5.1%) and -pinene (5.0%). The antioxidant capacity of the essential oil was evaluated in vitro by 2,2-Diphenyl-1-picrylhydrazyl (DPPH) scavenging, 2,2-azino-bis-3-ethylbenzothiazoline-6 sulfonic acid (ABTS) radical cation scavenging, hydroxyl radical (()) scavenging and chelating capacity, superoxide radical (()O(-)) scavenging and xanthine oxidase inhibitory effects, hydrogen peroxide scavenging. The antioxidant activity of the oil attributable to electron transfer made juniper berry essential oil a strong antioxidant, whereas the antioxidant activity attributable to hydrogen atom transfer was lower. Lipid peroxidation inhibition by the essential oil in both stages, i.e., hydroperoxide formation and malondialdehyde formation, was less efficient than the inhibition by butylated hydroxytoluene (BHT). In vivo studies confirmed these effects of the oil which created the possibility of blocking the oxidation processes in yeast cells by increasing activity of the antioxidant enzymes superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GPx).

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