Hu R.-H.,Kunming Military General Hospital |
He B.,Kunming Military General Hospital |
Liu L.,Kunming Military General Hospital |
Yan R.,Kunming Military General Hospital |
And 4 more authors.
Chinese Journal of Tissue Engineering Research | Year: 2013
Background: Although, the previous studies on acetabular morphological characteristics have yielded some results, quantitative description of the acetabular surface morphology has not yet been unified because of the special nature of acetabular structure and location, and this is bound to affect the accuracy of the diagnosis and treatment of hip disease. Objective: To investigate the CT measuring methods to acetabulum geometric parameters. Methods: Seventy cases performed CT scan were selected, including 50 normal adults (a total of 100 hips on both sides) and 20 cases with unilateral congenital hip dislocation. The hip CT images of the subjects were treated with coronal reconstruction and three-dimensional reconstruction, in order to compare the coronal and three-dimensional measurement value of acetabulum upper chamber, and to compare acetabulum upper camber between the normal side and the abnormal side in the congenital hip dislocation group. The acetabulum posterior abduction angle, anterior acetabulum index and posterior acetabular index were measured in the images in accordance with scan bed and the body coronal plane. Results and Conclusion: The acetabulum upper camber measured in coronal plane and three-dimensional image was (39.99±6.1)° and (40.13±5.80)° respectively, and there was no significant difference (P > 0.05). The acetabulum upper camber measured value of the unilateral congenital hip dislocation patients in normal side and abnormal side on coronal plane was (48.95±3.80)° and (63.56±6.35)°, and there were significant differences (P < 0.01). There were significant differences in acetabulum posterior abduction angle, anterior acetabulum index and posterior acetabular index measured in both sides on the images in accordance with scan bed and the body coronal plane (P < 0.01), and there were no significant differences in accordance with coronal plane (P > 0.05). The measurement is more reliable on the images in accordance with the body coronal plane when measuring acetabulum posterior abduction angle, anterior acetabulum index and posterior acetabular index. It can reflect the acetabular real condition and provide quantitative indicators for the diagnosis and treatment of hip disease.
Wang Y.-F.,Chongqing Medical University |
Wang Y.-F.,Kunming Military General Hospital |
Guo H.-F.,Chongqing Medical University |
Ying D.-J.,Chongqing Medical University
Journal of Biomedical Materials Research - Part B Applied Biomaterials | Year: 2013
Dural closure after the neurosurgery can prevent postoperative complications. Although many types of dural substitute have been developed, most of them lack functional and structural characteristics compared with the natural dura mater. In this study, we used electrospinning method to fabricate a multilayer scaffold to promote dural repair. The inner layer of the scaffold that faces the brain tissue is composed of poly-lactic acid (PLA) to reduce tissue adhesion. The middle layer of the scaffold is composed of poly-ε-caprolactone and PLA, which provides a watertight seal. The outer layer of the scaffold contains a large amount of collagen to promote cell attachment and proliferation. The results from in vitro study and an animal model have shown that this multilayer fibrous scaffold has sufficient mechanic strength and biochemical properties to enhance dural repair. Therefore, fabrication of scaffold with multiple functional and structural layers may provide a novel approach for tissue engineering. © 2013 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 101B: 1359-1366, 2013. Copyright © 2013 Wiley Periodicals, Inc.