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Kumamoto-shi, Japan

Kumamoto Health Science University is a private university in Kumamoto, Kumamoto, Japan, established in 2003. Wikipedia.

So H.,Ehime University | Takenaga K.,Kumamoto Health Science University
Physical Review D - Particles, Fields, Gravitation and Cosmology | Year: 2013

We introduce a four-dimensional cutoff in the scenario of gauge-Higgs unification to control the ultraviolet behavior. A one-loop effective potential for a Higgs field and the Higgs mass are obtained with the cutoff. We find an interrelation between the four-dimensional cutoff and the scale of extra dimensions, which is concretized through the Higgs mass. Combining this interrelation and the recently discovered Higgs boson at the LHC, we obtain an interesting constraint for the four-dimensional cutoff and the extra-dimensional scale. © 2013 American Physical Society.

Sugiuchi H.,Kumamoto Health Science University
Rinsho byori. The Japanese journal of clinical pathology | Year: 2012

Today, more than a decade after the development of direct methods for determining HDL-cholesterol (HDL-C) and LDL-cholesterol (LDL-C) concentrations, there are calls to review the reagents in response to discrepancies in patient samples with increased levels of atypical lipoproteins, such as apoE-rich HDL, IDL, Lp-X, and Lp-Y. Seven direct HDL-C assays showed different reactions toward apoE-rich HDL in sera from patients with CETP deficiency and cholestasis. On the other hand, the reactivity of the direct LDL-C assays to serum samples with elevated levels of IDL, Lp-X, and Lp-Y varied considerably between assay kits from each manufacturer. We have also examined the anti-atherogenic functions of apoE-rich HDL from the serum of healthy individuals and patients with CETP deficiency and cholestasis. The ability of apoE-rich HDL to remove cholesterol from cholesterol-loaded macrophages showed that the apoE-rich HDL from CETP-deficient serum took up more cholesterol than apoE-poor HDL (p < 0.01), but no significant differences were observed for apoE-rich HDL from patients with cholestasis.

Umehara A.,Prefectural University of Kumamoto | Tsutsumi H.,Prefectural University of Kumamoto | Takahashi T.,Kumamoto Health Science University
Environmental Science and Pollution Research | Year: 2012

Purpose: In the reservoir created in the reclaimed land in Isahaya Bay, Japan, Microcystis aeruginosa, which produces microcystins (MCs), bloomed every year, and the water with high levels of MCs in the reservoir has been often drained to Isahaya Bay to adjust the water level. The principal aims of this study are to clarify the water conditions suitable for blooming of M. aeruginosa in the reservoir, to follow the amount of distribution of MCs inside and outside the reservoir, and to discuss how blooming of M. aeruginosa is controlled in the reservoir and how MCs produced by Microcystis spread or accumulate in the aquatic environment. Method: We monitored the water quality (temperature, salinity, dissolved inorganic nitrogen (DIN), and dissolved inorganic phosphorus) in the reservoir with seasonal blooming of microalgae including phytoplankton and M. aeruginosa using the concentrations of chlorophyll α and MCs, respectively, and collected the surface sediment in the reservoir and the bay to determine the MC content using the ELISA method. Result: M. aeruginosa bloomed in extremely low DIN conditions of the water in warm seasons (spring and late summer to autumn). The year-mean standing stock of MCs was approximately 34. 5 kg in the water and 8. 4 kg in the surface sediment in the reservoir. Approximately 64. 5 kg of MCs was discharged with the effluent to the bay in a year. Conclusion: Since a large amount of MCs always suspends in the water in the reservoir and it has been discharged to the bay, suspension-feeding animals are exposed most seriously to the high levels of MCs occurring in these areas. We need to pay attention to the danger of widespread dispersal of MCs and biological concentration of MCs by fish and clam inside and outside the reservoir. © 2012 Springer-Verlag.

Hatanaka H.,Osaka University | Sakamoto M.,Kobe University | Takenaga K.,Kumamoto Health Science University
Physical Review D - Particles, Fields, Gravitation and Cosmology | Year: 2011

We discuss the gauge-Higgs unification in a framework of Lifshitz-type gauge theory. We study a higher-dimensional gauge theory on RD -1×S1 in which the normal second- (first-) order derivative terms for scalar (fermion) fields in the action are replaced by higher-order derivative ones for the direction of the extra dimension. We provide some mathematical tools to evaluate a one-loop effective potential for the zero mode of the extra component of a higher-dimensional gauge field and clarify how the higher-order derivative terms affect the standard form of the effective potential. Our results show that they can make the Higgs mass heavier and change its vacuum expectation value drastically. Some extensions of our framework are briefly discussed. © 2011 American Physical Society.

Kojima K.,Kyushu University | Takenaga K.,Kumamoto Health Science University | Yamashita T.,Nagoya University
Physical Review D - Particles, Fields, Gravitation and Cosmology | Year: 2011

We propose a novel way to break grand unified gauge symmetries via the Hosotani mechanism in models that can accommodate chiral fermions. Adjoint scalar fields are realized through the so-called diagonal embedding method which is often used in the heterotic string theory. We calculate the one-loop effective potential of the adjoint scalar field in a five dimensional model compactified on an S1/Z2 orbifold, as an illustration. It turns out that the potential is basically the same as the one in an S1 model, and thus the results in literatures, in addition to the chiral fermions, can be realized easily. © 2011 American Physical Society.

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