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Mangalore, India

Sudulagunta S.R.,Columbia Asia Hospital | Sodalagunta M.B.,KS Hegde Medical College | Khorram H.,Drbr Ambedkar Medical College | Sepehrar M.,Baptist Hospital | And 3 more authors.
GMS German Medical Science | Year: 2015

Neuromyelitis optica (NMO or Devic’s syndrome) is a rare relapsing demyelinating disease of the central nervous system (CNS) that mainly affects the spinal cord and optic nerves and shares many clinical and radiological features with multiple sclerosis. The association of NMO with other autoimmune diseases was reported, but very few reports described association with autoimmune thyroid disease. Early differentiation between NMO and multiple sclerosis is very important as the natural course and treatment regimens differ significantly. We report a case of a 50-year-old woman who was admitted initially with vomiting, hiccups and paraesthesias but was not diagnosed with NMO and presented with a severe progression of the disease. The patient was also diagnosed to have autoimmune thyroiditis with lymphocytic infiltration of the thyroid which progressed from hyperthyroidism to hypothyroidism. NMO diagnosis was established with seropositivity for NMO-IgG and MRI showing longitudinally extensive spinal cord lesions (3 or more spinal segments). In spite of treatment, the response was poor due to lack of early diagnosis and aggressive immunosuppressant therapy. © 2015 Sudulagunta et al. Source

Objectives: The objectives of the study are to: (i) Determine the learning needs of staff nurses, auxiliary nurse midwives and lady health visitors on maternal and child health care. (ii) Determine the level of knowledge and selected maternal and child health care practices of staff nurses, auxiliary nurse midwives and lady health visitors on maternal and child health care before and after the implementation of the educational intervention program. (iii) Evaluate the effectiveness of maternal and child health educational intervention program. Materials and methods: This evaluative study at selected health centers of Udupi district in India enrolled 50 staff nurses, auxiliary nurse midwives and lady health visitors who were currently employed. Results: Major findings of the study were: There was a significant improvement (p < 0.05) in the performance skill related to antenatal, postnatal and newborn. Conclusion: The training was effective in improving the overall performance of the workers. However, repeated in-service training is necessary in maintaining the levels of improvement. Source

Poojary R.J.,Manipal University India | Kumari S.,KS Hegde Medical College | Nayanatara A.K.,Manipal University India | Shiva R.K.,Manipal University India | And 2 more authors.
Research Journal of Pharmaceutical, Biological and Chemical Sciences | Year: 2016

Oral pre cancer is a lesion found in the oral cavity and oropharynx. Sialic acid (N-acetyl neuraminic acid) and L-fucose (6 deoxy-L galactose) are the monosacharides present in the mammalian cells. Literature review has showed a clear link between these monosaccharides and various carcinomas. Objectives of the present study is to estimate and compare the status of Sialic acid and L-fucose in precancerous patients. Present study is conducted in compliance with the ethical committee guidelines of the institute. Sixty subjects with the age range 20-60 years were included in the current study. The study group included clinically diagnosed cases of oral sub mucous fibrosis, leukoplakia and erythroplakia. These were clinically confirmed cases of oral pre-cancer. L-fucose and sialic acid were measured by Winzlers method in serum sample. The levels of Sialic acid and L-fucose were found to be increased significantly increased in various stages of pre cancer in comparison with the normal subjects (p > 0.001). When pre-cancer develops, cell to cell adhesiveness is diminished among these cells and they easily enter into the blood stream. The level of serum Sialic acid and L-Fucose increases along with the severity and inflammation of the tissues. © 2010 RJPBCS. Source

Pavithra S.,Skin and Cosmetology Center | Mallya H.,KS Hegde Medical College | Pai G.,Skin and Cosmetology Center
Indian Journal of Dermatology | Year: 2012

The cardiofaciocutaneous (CFC) syndrome is a condition of sporadic occurrence, with patients showing multiple congenital anomalies and mental retardation and characteristic dysmorphic features. We, thus, report a rare case of this syndrome in a 1-year-old child who presented with typical features of CFC syndrome. Source

Pavithra S.,Care Skin and Cosmetology Center | Mallya H.,KS Hegde Medical College | Pai G.,Derma Care Skin and Cosmetology Center
Indian Journal of Dermatology | Year: 2011

A 27-year-old healthy man presented with non-itchy hyperpigmented skin lesions involving the trunk of duration 3 years. Examination revealed numerous coalescing, rough, slightly elevated brownish papules involving large areas of back, chest, and abdomen. There were no other cutaneous or systemic findings. Cutaneous biopsy was suggestive of verruca plana, which confirmed our clinical diagnosis. Here, we report this case of verruca plana due to its rare extensive involvement and unusual site in a non-immunocompromised individual. Source

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