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Sudulagunta S.R.,Columbia Asia Hospital | Sudulagunta S.R.,Dr Br Ambedkar Medical College | Kumbhat M.,Sri Ramachandra Medical College | Sodalagunta M.B.,Ks Hegde Medical College | And 2 more authors.
Oxford Medical Case Reports | Year: 2017

Brucellosis is a zoonotic infectious disease, which can attack any organ of the body but mainly involves lymphoreticular system. Our case report describes isolated splenic abscess diagnosed in a 50-year-old individual who is a milk vendor by occupation and has the habit of consuming raw milk. He was admitted with pain abdomen, high-grade fever with chills, generalized malaise, night sweats and weight loss. Ultrasound and computerized tomography of the abdomen showed splenomegaly and hypodense, nonenhancing lesion measuring 3.2 × 2.8 × 2.8 cm. Brucella slide and tube agglutination tests (Wright, at 1/640) were positive. The patient was successfully treated with percutaneous drainage along with oral doxycycline (200 mg/day) and rifampin (600 mg/day) for 6 weeks. A high index of suspicion is required for early detection, prompt treatment and prevention of complications of brucellosis, especially in endemic areas. Patients with fever of unknown origin should be evaluated for brucellosis. © The Author 2017.


Objectives: The objectives of the study are to: (i) Determine the learning needs of staff nurses, auxiliary nurse midwives and lady health visitors on maternal and child health care. (ii) Determine the level of knowledge and selected maternal and child health care practices of staff nurses, auxiliary nurse midwives and lady health visitors on maternal and child health care before and after the implementation of the educational intervention program. (iii) Evaluate the effectiveness of maternal and child health educational intervention program. Materials and methods: This evaluative study at selected health centers of Udupi district in India enrolled 50 staff nurses, auxiliary nurse midwives and lady health visitors who were currently employed. Results: Major findings of the study were: There was a significant improvement (p < 0.05) in the performance skill related to antenatal, postnatal and newborn. Conclusion: The training was effective in improving the overall performance of the workers. However, repeated in-service training is necessary in maintaining the levels of improvement.


Pavithra S.,Care Skin and Cosmetology Center | Mallya H.,KS Hegde Medical College | Pai G.,Derma care Skin and Cosmetology Center
Indian Journal of Dermatology | Year: 2011

A 27-year-old healthy man presented with non-itchy hyperpigmented skin lesions involving the trunk of duration 3 years. Examination revealed numerous coalescing, rough, slightly elevated brownish papules involving large areas of back, chest, and abdomen. There were no other cutaneous or systemic findings. Cutaneous biopsy was suggestive of verruca plana, which confirmed our clinical diagnosis. Here, we report this case of verruca plana due to its rare extensive involvement and unusual site in a non-immunocompromised individual.


PubMed | Ks Hegde Medical College, Columbia Asia Hospital, Drbr Ambedkar Medical College and Baptist Hospital
Type: | Journal: German medical science : GMS e-journal | Year: 2015

Guillain-Barr syndrome (GBS) is a fulminant polyradiculoneuropathy that is acute, frequently severe and autoimmune in nature. Etiology of GBS is incompletely understood, prognosis is usually good with early detection and prompt treatment. This retrospective study was done to evaluate clinical profile, epidemiological, laboratory, and electrodiagnostic features of patients with GBS and mode of management, complications and prognostic factors.Data of 1,166 patients admitted with GBS or presented to outpatient department (previous medical records) with GBS between January 2003 and January 2014 were analyzed.No difference in genders noted. Around 35% of patients are above 50 years of age. Poor control of diabetes with mean HbA1c of 8.1 2.11 is found on analysis. Seasonal occurrence in GBS is prominent in winter 484 (41.50%) and mechanically ventilated were 449 (38.50%) patients. 48 (4.11%) deaths were attributed to GBS. Neurological analysis revealed cranial nerve involvement in 407 (34.90%) patients, facial palsy in 401 (34.39%) and ataxia in 88 (7.54%) patients. Most patients in plasma exchange group belonged to the lower socio-economic status. Mean cerebrospinal fluid (CSF) protein levels was (n=962) 113.8 11.8 mg/dl. Conduction block determined indirectly by absent H-reflex was noted in 891 (90.64%) patients. No difference in complications and outcome is found in treatment regimens of intravenous immunoglobulin (IVIG) and plasma exchange.Seasonal occurrence predominantly in winter is noted. Peak flow test may be a predictor of assessing requirement of mechanical ventilation and prognosis. Conduction block is the major abnormality noted in electrophysiological studies and proximal nerve segment assessing with Erbs point stimulation has high predictive value. IVIG treatment is more expensive but is associated with less duration of hospital stay.


PubMed | Ks Hegde Medical College, Columbia Asia Hospital, Baptist Hospital and Dr Br Ambedkar Medical College
Type: Journal Article | Journal: Oxford medical case reports | Year: 2015

Neuromyelitis optica (NMO or Devics syndrome) is a rare demyelinating disease of the CNS that predominantly affects the spinal cord and optic nerves and shares many clinical and radiological features with multiple sclerosis (MS). The association of NMO with autoimmune thyroiditis has been reported very rarely. Early differentiation between NMO and MS is very important because they have different natural courses and treatment regimens. We report a case regarding a 53-year-old woman who was admitted initially with hiccups and paraesthesias, but was not evaluated during first two episodes and presented with severe progression of NMO. Patient was found to have autoimmune thyroiditis with lymphocytic infiltration of thyroid which progressed to hypothyroidism. NMO was diagnosed with seropositivity for NMO-IgG and longitudinally extensive spinal cord lesions (three or more spinal segments). Patient poorly responded to treatment due to the lack of early diagnosis and aggressive immunosuppressant therapy.


PubMed | Ks Hegde Medical College, Columbia Asia Hospital, Drbr Ambedkar Medical College and Baptist Hospital
Type: | Journal: German medical science : GMS e-journal | Year: 2015

Neuromyelitis optica (NMO or Devics syndrome) is a rare relapsing demyelinating disease of the central nervous system (CNS) that mainly affects the spinal cord and optic nerves and shares many clinical and radiological features with multiple sclerosis. The association of NMO with other autoimmune diseases was reported, but very few reports described association with autoimmune thyroid disease. Early differentiation between NMO and multiple sclerosis is very important as the natural course and treatment regimens differ significantly. We report a case of a 50-year-old woman who was admitted initially with vomiting, hiccups and paraesthesias but was not diagnosed with NMO and presented with a severe progression of the disease. The patient was also diagnosed to have autoimmune thyroiditis with lymphocytic infiltration of the thyroid which progressed from hyperthyroidism to hypothyroidism. NMO diagnosis was established with seropositivity for NMO-IgG and MRI showing longitudinally extensive spinal cord lesions (3 or more spinal segments). In spite of treatment, the response was poor due to lack of early diagnosis and aggressive immunosuppressant therapy.


Pavithra S.,Skin and Cosmetology Center | Mallya H.,KS Hegde Medical College | Pai G.,Skin and Cosmetology Center
Indian Journal of Dermatology | Year: 2012

The cardiofaciocutaneous (CFC) syndrome is a condition of sporadic occurrence, with patients showing multiple congenital anomalies and mental retardation and characteristic dysmorphic features. We, thus, report a rare case of this syndrome in a 1-year-old child who presented with typical features of CFC syndrome.


D'souza C.,KS Hegde Medical College | Bhagavan K.R.,KS Hegde Medical College | Rakesh K.,KS Hegde Medical College
Journal of Clinical and Diagnostic Research | Year: 2012

Gall bladder injuries which are caused after a blunt trauma in the abdomen are rare and they have significant mortality and morbidity when the treatment is delayed. They usually go undiagnosed until an exploratory laparotomy is done. We are reporting here a case of isolated gall bladder neck perforation, which is an uncommon finding following a blunt injury in the abdomen.


Poojary R.J.,Manipal University India | Kumari S.,KS Hegde Medical College | Nayanatara A.K.,Manipal University India | Shiva R.K.,Manipal University India | And 2 more authors.
Research Journal of Pharmaceutical, Biological and Chemical Sciences | Year: 2016

Oral pre cancer is a lesion found in the oral cavity and oropharynx. Sialic acid (N-acetyl neuraminic acid) and L-fucose (6 deoxy-L galactose) are the monosacharides present in the mammalian cells. Literature review has showed a clear link between these monosaccharides and various carcinomas. Objectives of the present study is to estimate and compare the status of Sialic acid and L-fucose in precancerous patients. Present study is conducted in compliance with the ethical committee guidelines of the institute. Sixty subjects with the age range 20-60 years were included in the current study. The study group included clinically diagnosed cases of oral sub mucous fibrosis, leukoplakia and erythroplakia. These were clinically confirmed cases of oral pre-cancer. L-fucose and sialic acid were measured by Winzlers method in serum sample. The levels of Sialic acid and L-fucose were found to be increased significantly increased in various stages of pre cancer in comparison with the normal subjects (p > 0.001). When pre-cancer develops, cell to cell adhesiveness is diminished among these cells and they easily enter into the blood stream. The level of serum Sialic acid and L-Fucose increases along with the severity and inflammation of the tissues. © 2010 RJPBCS.


D'Souza C.,Ks Hegde Medical College | Rajashekar,Ks Hegde Medical College | Bhagavan K.R.,Ks Hegde Medical College
Journal of Clinical and Diagnostic Research | Year: 2012

False cysts of spleen or the pseudocysts accounts for about 75% of the non-parasitic splenic cysts and are usually traumatic in origin. These cysts are differentiated from the true cysts of the spleen by a absence of a epithelial layer on histology. We present here a case of a giant splenic pseudocyst in a young female with no previous history of trauma.

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