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Islamabad, Pakistan

Khan T.H.,KRL General Hospital
Anaesthesia, Pain and Intensive Care | Year: 2012

Plagiarism is a universal phenomenon, not strictly restricted to medical writing, but encompassing almost all fields of life. Over a period of time, it has become customary to talk very loudly about it and even condemn it as a sin. A review of the past and present scientific knowledge as well as literature confirms that plagiarism has been and is still in wide practice in developed as well as undeveloped countries. The availability of scientific knowledge on the internet has made it easier to plagiarise as well as to identify plagiarized material. On the other hand much of the research methodology, reviews, discussion pans of original articles and even larger books and monographs do contain parts of copied material from already published material. This editorial review the prevalence of and the measures to control the plagiarism, and stresses a need to draw fresh lines in between good and bad plagiarism. Source

Taqi A.,Hameed Latif Hospital | Khan T.H.,KRL General Hospital
Anaesthesia, Pain and Intensive Care | Year: 2013

The journal presents this special issue dedicated to drug errors, with just two aspects highlighted; syringe swap and inadvertent wrong drug administration due to look-alike drug containers. This article gives the background of this decision and a victim's vivid narrative of her terrific experience related to drug error during anesthesia. Source

Khan T.H.,KRL General Hospital
Anaesthesia, Pain and Intensive Care | Year: 2015

Pain is usually regarded as of two types, pain caused by tissue damage, also called nociceptive pain, and pain caused by nerve damage, also called neuropathic pain. A less known third category is psychogenic pain, which becomes an integral part, in due course of time, of the first two types. It is pain that is affected by psychological factors. Pain physicians tens to focus usually on the first, less commonly on the second and very rarely on the last type of pain. This ignorance may be the prime factor in failure of otherwise more rational pain management regimen. It needs to be adequately addressed, and expert help from qualified psychologist and/or a psychiatrist may be required in selected patients to incorporate body-mind techniques in the pain management. Source

Mansoor Q.,Institute of Biomedical and Genetic Engineering IB&GE | Bilal N.,PIMS | Qureshi S.,KRL General Hospital | Qureshi O.,KRL General Hospital | And 2 more authors.
International Journal of Diabetes and Metabolism | Year: 2010

Type 2 diabetes mellitus (T2DM) has become a global problem. Type 2 diabetes mellitus is accelerating pandemic in the Pakistani population as well. The problem progresses with severity of diabetic complications. Diabetic nephropathy (DN) is the most fatal of all these complications. Diabetic nephropathy leads to end stage renal disease if glycemic control and microvascular protection is inadequate. Angiotensin converting enzyme (ACE) gene polymorphism has been reported to be associated with the diabetic nephropathy in type 1 and type 2 diabetes mellitus. ACE plays crucial roles in regulation of rennin angiotensin system. Use of ACE inhibitors and angiotensin receptor blockers (ARBs) can prevent diabetic renal damage. The purpose of this study is to investigate the association of Insertion/deletion (I/D) polymorphism of 287 bp Alu repetitive sequence in intron 16 of ACE gene with diabetic nephropathy. The study includes 284 T2DM Pakistani patients out of which 84 patients developed DN and 108 control subjects. Gender specific ACE gene association was observed in this study. Insertion (I) allele of ACE gene was found to be associated with progression of DN in men with type 2 diabetes mellitus. We did not get any significant association of I allele in women with DN. Neuropathy and family history were strongly associated with progression of diabetic nephropathy. The study will help administer T2DM patients with diabetic nephropathy in Pakistani ethnic groups. Prospective studies need to determine the role of ACE gene I/D polymorphism in Pakistani men with diabetic nephropathy. Source

Khan T.H.,KRL General Hospital
Anaesthesia, Pain and Intensive Care | Year: 2013

The incidence of transfusion has increased day by day due to many factors, including increasing population, enhanced expertise and facilities to operate once inoperable conditions and the willingness of the public to pay high cost of advanced surgical procedures. Trauma services have been well-organized now and victims may have massive transfusion. Many authors have pointed out the need of protocols and guidelines to be followed to avoid transfusion associated risks and complications. Under-transfusion has been preferred to over-transfusion and a need to have a 'Maximum Surgical Blood Order Schedule' has been stressed. Source

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