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Indore, India

Krishna University was established in Machilipatnam Krishna district Andhra Pradesh, India, in 2008. It was established by the state of Andhra Pradesh. Facilities include laboratories, internet, reading room, guest house, and extra-curricular activities. Wikipedia.

Jayasankaraprasad C.,Krishna University | Kathyayani G.,JNTUH College of Engineering
International Review of Retail, Distribution and Consumer Research | Year: 2014

The main purpose of this study is to explore cross-format shopping motives among grocery consumers and to categorise cross-format shopping typologies based on identified motives. The paper also aims to identify common consumer subgroups amongst the customer base of different retail formats and differences among shopper segments in relation to format choice and repeat patronage (loyalty). In this method, exploratory qualitative (semi-structured personal interviews) and quantitative research (mall intercept survey) approaches were used. Primary data were collected from 1040 grocery consumers by self-administering a structured questionnaire. Multivariate techniques including exploratory factor analysis, k-means cluster analysis, multiple discriminant analysis, multivariate analysis of variance, and χ2 tests were applied to test the formulated propositions. This paper identifies nine cross-format shopping motivations: value for money, value for time, price-conscious, local shopping, shopping enjoyment, social shopping, variety seeking, entertainment, and brand-conscious motives. Based on these central dimensions, this paper finds five cross-format shopper segments: economic shopper, convenience shopper, price-promotional shopper, hedonic shopper, and social shopper. The study also indicates that there are significant differences amongst shopper typologies in relation to retail format choice and repatronage. This study provides specific knowledge of the cross-shopping motives to the grocery retailers that consumers consider important when making format choices. The study also helps retailers develop various retailing strategies to increase store format loyalty. Despite the importance of understanding grocery consumers' cross-shopping, little research has been conducted to investigate the growing incidence of cross-format shopping. Given the absence of published academic literature in relation to cross-format shopping behaviour in the context of emerging retail markets, the empirical evidence may serve as a departure point for future studies in this area of concern. The research is relevant to grocery retailers in terms of format development. © 2013 Taylor & Francis. Source

Obulesu M.,Rayalaseema University | Dowlathabad M.R.,Andhra University | Bramhachari P.V.,Krishna University
Neurochemistry International | Year: 2011

Carotenoids play a pivotal role in prevention of many degenerative diseases mediated by oxidative stress including neurodegenerative diseases like Alzheimer's Disease (AD). The involvement of retinoids in physiology, AD pathology and their therapeutic role in vitro and in vivo has been extensively studied. This review focuses on the role of carotenoids like retinoic acid (RA), all trans retinoic acid (ATRA), lycopene and β-carotene in prevention of AD symptoms primarily through inhibition of amyloid beta (Aβ) formation, deposition and fibril formation either by reducing the levels of p35 or inhibiting corresponding enzymes. The role of antioxidant micronutrients in prevention or delaying of AD symptoms has been included. This study emphasizes the dietary supplementation of carotenoids to combat AD and warrants further studies on animal models to unravel their mechanism of neuroprotection. © 2011 Elsevier B.V. All rights reserved. Source

Bodiga V.L.,Krishna University | Eda S.R.,Koneru Lakshmaiah College of Engineering | Bodiga S.,Koneru Lakshmaiah College of Engineering
Heart Failure Reviews | Year: 2014

Increasing evidence demonstrates that advanced glycation end products (AGEs) play a pivotal role in the development and progression of diabetic heart failure, although there are numerous other factors that mediate the disease response. AGEs are generated intra- and extracellularly as a result of chronic hyperglycemia. Then, following the interaction with receptors for advanced glycation end products (RAGEs), a series of events leading to vascular and myocardial damage are elicited and sustained, which include oxidative stress, increased inflammation, and enhanced extracellular matrix accumulation resulting in diastolic and systolic dysfunction. Whereas targeting glycemic control and treating additional risk factors, such as obesity, dyslipidemia, and hypertension, are mandatory to reduce chronic complications and prolong life expectancy in diabetic patients, drug therapy tailored to reducing the deleterious effects of the AGE-RAGE interactions is being actively investigated and showing signs of promise in treating diabetic cardiomyopathy and associated heart failure. This review shall discuss the formation of AGEs in diabetic heart tissue, potential targets of glycation in the myocardium, and underlying mechanisms that lead to diabetic cardiomyopathy and heart failure along with the use of AGE inhibitors and breakers in mitigating myocardial injury. © Springer Science+Business Media 2013. Source

Kshirsagar V.Y.,Krishna University
Acta medica academica | Year: 2012

Pycnodysostosis is a rare autosomal recessive disorder whose gene responsible for this phenotype (CTSK), mapped to human chromosome 1q21, code for the enzyme cathepsin K, a lysosomal cysteine protease; with an estimated incidence of 1.7 per 1 million births. This clinical entity includes micromelic dwarfism, increased radiological bone density, dysplasia of the skull, acro-osteolysis, straightening of the mandibular angle and in some cases, dysplasia of the acromial end of the clavicle. Oral and maxillo-facial manifestations of this disease are very clear. Herein we reported a case of pycnodysostosis, showing short stature with widening of the sutures, unfused anterior and posterior fontanelles, crowding of teeth with dental caries and typical radiological features associated with ichthyosis vulgaris and palmoplantar keratoderma. Copyright © 2012 by Academy of Sciences and Arts of Bosnia and Herzegovina. Source

Krishna University | Date: 2012-01-05

A set of color coded rings consisting of one subset of even numbers and other subset of odd numbers together is indicative of serially increasing cervical dilatation from 4 cm. to 9 cm. Vaginal examination with all aseptic precautions is to be carried out every 2 to 4 hours for each delivering woman. Size and color of the ring corresponding to actual cervical dilatation is to be identified. Next ring of the same color indicates expected cervical dilatation at the end of every 2 hours. If the expected cervical dilatation is not reached within the stipulated period of time, it indicates slow progress of labor and need for intervention/referral. It is an alternative for cervicograph which is easy to understand and use by clinical as well as para-clinical personnel during delivery.

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