Krishna Institute of Engineering and Technology
Ghaziabad, India

Krishna Institute Of Engineering And Technology is a private engineering institute affiliated to Uttar Pradesh Technical University, situated in the Ghaziabad in the National Capital Region of India 30 km from Delhi. The institute is ISO certified. It consists of 10 academic departments with a focus on education in engineering, science, pharmacy and management. The institute has ties with industry, and offers on-campus placements where students get placed with different companies. Wikipedia.

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Nagarajan K.,Krishna Institute of Engineering and Technology
Saudi Pharmaceutical Journal | Year: 2013

The objective of the article is to highlight various roles of glutamic acid like endogenic anticancer agent, conjugates to anticancer agents, and derivatives of glutamic acid as possible anticancer agents. Besides these emphases are given especially for two endogenous derivatives of glutamic acid such as glutamine and glutamate. Glutamine is a derivative of glutamic acid and is formed in the body from glutamic acid and ammonia in an energy requiring reaction catalyzed by glutamine synthase. It also possesses anticancer activity. So the transportation and metabolism of glutamine are also discussed for better understanding the role of glutamic acid. Glutamates are the carboxylate anions and salts of glutamic acid. Here the roles of various enzymes required for the metabolism of glutamates are also discussed. © 2013.

Singh B.K.,Krishna Institute of Engineering and Technology | Haque S.E.,Hamdard University | Pillai K.K.,Hamdard University
Expert Opinion on Drug Metabolism and Toxicology | Year: 2014

Introduction: Nonsteroidal anti-inflammatory drugs (NSAIDs), including selective cyclooxygenase-2 inhibitors (coxibs) and traditional NSAIDs (tNSAIDs), have been widely used for the treatment of pain and rheumatic disease. The use of NSAIDs has been linked to increased cardiovascular toxicity in both healthy individuals and patients with established cardiovascular disease. Various recently published studies have raised concerns about the cardiovascular safety of NSAIDs; this review is focused on the cardiotoxic effects of NSAIDs. Areas covered: This review focuses on arthritis trials, placebo-controlled trials, meta-analyses, preclinical and observational studies associated with the use of NSAIDs-induced cardiotoxicity. It analyses the data given in these studies and discusses the cardiotoxic risk of NSAIDs. Expert opinion: Analysis of various clinical, preclinical, meta-analysis and observational studies showed that coxibs and tNSAIDs increase the risk of cardiotoxicity. Cardiotoxic risk depends on dose, duration and frequency of NSAID administration. Most studies were based on large medical databases with miscellaneous populations and pointed to an increase risk of cardiotoxicity under NSAID medication. The cardiotoxicity associated with use of NSAIDs might be due to inhibition of prostacyclin synthesis, oxidative stress, increase in blood pressure and impaired endothelial function. © Informa UK, Ltd.

Shukla A.P.,Krishna Institute of Engineering and Technology
Romanian Journal of Information Science and Technology | Year: 2016

Cellular automata can be significantly applied in image processing tasks. In this paper, a novel method to train two dimensional cellular automata for detection of edges in digital images has been proposed and experiments have been carried out for the same. Training of two dimensional cellular automata means selecting the optimum rule set from the given set of rules to perform a particular task. In order to train the cellular automata first, the size of rule set is reduced on the basis of symmetry. Then the sequential floating forward search method for rule selection is used to select the best rule set for edge detection. The misclassification error has been used as an objective function to train the cellular automata for edge detection. The whole experiment has been divided in two parts. First the training was performed for binary images then it is performed for gray scale images. A novel method of thresholding the image by Otsu's algorithm and then applying the cellular automata rules for the training purpose has been proposed. It has been observed that the proposed method significantly decreases the training time without affecting the results. Results are validated and compared with some standard edge detection methods both qualitatively and quantitatively and it is found better in terms of detecting the edges in digital images. Also the proposed method performs much better in corner detection as compared to the standard edge detection methods.

Sandeep,Krishna Institute of Engineering and Technology | Kumar S.,National Institute of Technology Kurukshetra | Dwivedi V.K.,GCET
Desalination | Year: 2015

In this present study an attempt has been made to enhance the productivity of a basin type single slope active solar still with improved condensation technique. A new design having additional condensing cover has been proposed and study of its performance was carried out throughout the year. Due to extra condensing surface, higher yield was observed as compared to conventional single slope still. It was experimentally found that water depth, shading on condensing surface and material of extra condensing surface have significant roles in the distillate output of the proposed new design. The yield of the proposed solar still was found to be 3.015kg/m2/day on a particular day in April '12 which was about 25% more than that of a conventional solar still running in parallel under the same climatic conditions. This paper also aimed at finding an optimum design condition of a new model for better productivity. Additional increment in yield up to 14.5% was also observed with further modifications in the design. © 2015 Elsevier B.V.

Kumar V.,Krishna Institute of Engineering and Technology | Dwivedi D.K.,Madan Mohan Malaviya University of Technology
Optik | Year: 2013

Thin films of CdS0.5Se0.5 have been deposited on ultra-clean glass substrates by screen-printing method followed by sintering process. Cadmium sulphide, cadmium selenide and cadmium chloride have been used as the basic source material. Optimum conditions for preparing good quality screen-printed films have been found. X-ray diffraction studies revealed that the films are polycrystalline in nature, exhibiting wurtzite (hexagonal) structure with strong preferential orientation of grains along the (0 0 2) direction. The optical band gap of the films has been studied using reflection spectra in wavelength range 350-900 nm by using double beam spectrophotometer. The electrical resistivity of the films was measured in vacuum by two probe technique. © 2012 Elsevier GmbH.

Goswami N.,CINVESTAV | Goswami N.,Jaypee Institute of Information Technology | Sharma D.K.,Krishna Institute of Engineering and Technology
Physica E: Low-Dimensional Systems and Nanostructures | Year: 2010

In this paper we report the structural, electronic and optical properties of ZnO nanocrystals synthesized by a facile chemical method. ZnO nanoparticles prepared by this method were investigated employing X-ray diffraction (XRD), Transmission electron microscope (TEM), Atomic force microscope (AFM), Fourier transform infrared (FTIR), UV-Visible and Fluorescence (FL) spectroscopy. In order to study the effect of annealing on ZnO nanoparticles, we have analyzed pre- and post-annealed nanoparticles. It was observed that annealing treatment removes the impurities and consequently enhances the purity of ZnO nanoparticles without influencing their wurtzite phase. The absorption and excitation transitions occurring in annealed ZnO nanoparticles are similar to those in unannealed ZnO; however, some fluorescence emissions are altered. On the one hand, annealing assists in obtaining the pure ZnO nanoparticles without affecting their size and crystal structure; on the other hand channels of radiative combination are affected by the annealing process. © 2010 Elsevier B.V. All rights reserved.

Kumar S.,Indian Institute of Technology Delhi | Tiwari A.,Krishna Institute of Engineering and Technology
Energy Conversion and Management | Year: 2010

Two solar stills (single slope passive and single slope photovoltaic/thermal (PV/T) active solar still) were fabricated and tested at solar energy park, IIT New Delhi (India) for composite climate. Photovoltaic operated DC water pump was used between solar still and photovoltaic (PV) integrated flat plate collector to re-circulate the water through the collectors and transfer it to the solar still. The newly designed hybrid (PV/T) active solar still is self-sustainable and can be used in remote areas, need to transport distilled water from a distance and not connected to grid, but blessed with ample solar energy. Experiments were performed for 0.05, 0.10, and 0.15 m water depth, round the year 2006-2007 for both the stills. It has been observed that maximum daily yield of 2.26 kg and 7.22 kg were obtained from passive and hybrid active solar still, respectively at 0.05 m water depth. The daily yield from hybrid active solar still is around 3.2 and 5.5 times higher than the passive solar still in summer and winter month, respectively. The study has shown that this design of the hybrid active solar still also provides higher electrical and overall thermal efficiency, which is about 20% higher than the passive solar still. © 2010 Elsevier Ltd. All rights reserved.

Dwivedi V.K.,Krishna Institute of Engineering and Technology | Tiwari G.N.,Center for Energy Studies
Desalination | Year: 2010

In this paper, thermal modeling of a double slope active solar still has been carried out on the basis of energy balance of east and west glass covers, water mass and basin liner under natural circulation mode. The thermal model of distillation system has been validated for hourly data for inner and outer glass cover temperatures, water temperature and the yield. The hourly thermal and exergy efficiency of active solar still have also been evaluated for 0.03 m water depth. It has been observed that the thermal efficiency of double slope active solar still is lower than the thermal efficiency of double slope passive solar still. However, the exergy efficiency of double slope active solar still is higher than the exergy efficiency of double slope passive solar still. All numerical calculations have been performed for a typical day in the month of March 2008 for the composite climate of Ghaziabad (28°40′N, 77°25′E), U.P, India. © 2009 Elsevier B.V. All rights reserved.

Sharma A.,Krishna Institute of Engineering and Technology | Agarwal S.,Krishna Institute of Engineering and Technology
Research Journal of Information Technology | Year: 2012

Pattern Analysis has currently become a topic of discussion. A lot of research has been done in the field of Complex Pattern Analysis. It involves automatic detection of patterns in data from the same source and making prediction of the new data coming from the same source. Various techniques were developed which took either one or multiple dimensionalities into account to analyze the existing patterns and predicting the future values. Temperature prediction is a complex process and a challenging task for researchers. It includes expertise in multiple disciplines. The prediction of atmospheric parameters is essential for various applications. Some of them include climate monitoring, drought detection, severe weather prediction, agriculture and production, planning in energy industry, aviation industry, communication, pollution dispersal etc. Accurate prediction of weather parameters is a difficult task due to the dynamic nature of atmosphere. Various models have been developed for predicting the temperature which is based on neural network, fuzzy approach etc. In this paper, wavelet neural network approach is used for temperature prediction. This paper aimed in using wavelet neural networks approach using multiple factors to predict the data values. Temperature data of Taipei, Taiwan of the year 1995-96 is used for result verification. The results obtained are compared with that of other techniques and are found to be better. © 2012 Academic Journals Inc.

Tyagi K.,Ajay Kumar Garg Engineering College | Sharma A.,Krishna Institute of Engineering and Technology
Advances in Engineering Software | Year: 2012

Reliability is one of the most important nonfunctional requirements for software. Accurately estimating reliability for component-based software systems (CBSSs) is not an easy task, and researchers have proposed many approaches to CBSS reliability estimation. Some of these approaches focus on component reliability and others focus on glue code reliability. All of the approaches that have been proposed are mathematical. However, because reliability is a real-world phenomenon with associated real-time issues, it cannot be measured accurately and efficiently with mathematical models. Soft computing techniques that have recently emerged can be used to model the solution of real-world problems that are too difficult to model mathematically. The two basic soft computing techniques are fuzzy computing and probabilistic computing. In this paper, we focus on four factors that have the strongest effect on CBSS reliability. Based on these four factors, we propose a new fuzzy-logic-based model for estimating CBSS reliability. We implemented and validated our proposed model on small applications, and the results confirm the effectiveness of our model. © 2012 Elsevier Ltd. All rights reserved.

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