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Tomita K.,Koukankai Tsurumi Occupational Health Center | Yokoyama T.,Japan National Institute of Public Health
Obesity | Year: 2010

The location of waist circumference (WC) measurement differs among diagnostic guidelines for the metabolic syndrome. The present study examined which of four WC measurements was associated most strongly with the clustering of metabolic risk factors in cross-sectional study. The subjects comprised 1,140 Japanese employees, aged 20-70 years, who underwent health examinations in 2007 and 2008. WC was measured at (i) the narrowest part of the waist, (ii) midway between the lowest rib and the iliac crest, (iii) the umbilical level, and (iv) immediately above the iliac crest. A receiver operator characteristic (ROC) curve was used to assess the ability of each WC measurement to predict the presence of two or more other components of the metabolic syndrome, as defined by the National Cholesterol Education Program's Adult Treatment Panel III (NCEP-ATP III) in 2005. Multiple risk factors were seen in 43.0% of the men and 12.9% of the women. The minimum and maximum WC measurements differed by 3.9cm among the men and 12.6cm among the women. The areas under the curve examining the ability of the four WC measurements to predict the clustering of multiple risk factors were similar. If the same WC cutoff value was applied, the prevalence of the metabolic syndrome changed considerably according to the site of WC measurement. The four WC measurements had similar screening abilities. Given the differences in the WC values according to the site of measurement, WC must be measured at the site specified by each diagnostic guideline. © 2010 The Obesity Society.

Nanri A.,International Clinical Research Center | Tomita K.,Mitsubishi Group | Matsushita Y.,International Clinical Research Center | Ichikawa F.,Koukankai Tsurumi Occupational Health Center | And 4 more authors.
Journal of Occupational Health | Year: 2012

Objectives: The prevalence of metabolic syndrome (MS) has been remarkably increasing worldwide. However, few studies have examined the effect of lifestyle intervention among subjects with MS. We investigated the effect of a sixmonth lifestyle modification program on the prevalence of MS and its associated biomarkers among Japanese men with MS. Methods: Subjects were randomly assigned to either the intervention (n=53) or control (n=54) group. Subjects in the intervention group received a lifestyle modification program focused on exercise and diet behavior from a trained occupational health nurse at the baseline and at one and three months. The effect of intervention was assessed by differences in changes in the prevalence of MS, its components and associated biomarkers between the two groups. Results: Of the 107 participants, 102 completed the survey at the end of six months (intervention group, n=49; control group, n=53). During the study period, the prevalence of MS decreased to 65.3% and 62.3% in the intervention group and control group, respectively. However, the difference between the two groups was not statistically significant (p=0.75). A significant reduction in body weight, waist circumference and glycated hemoglobin was observed in the intervention group compared with the control group. In the intervention group, time spent on physical activity was increased by nearly one hour per week, and the intakes of cereals and sugar and sweeteners were significantly decreased. Conclusions: Although the tailor-made lifestyle modification program among men with MS did not provide an additional benefit in decreasing the prevalence of MS, it may help weight control and improve glucose metabolism.

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