Korea Institute Radiological and science

Seoul, South Korea

Korea Institute Radiological and science

Seoul, South Korea
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Jung Y.-J.,Korea Institute Radiological and Science | Jung Y.-J.,Korea University | Kim K.,Korea Institute Radiological and Science | Lee K.,Korea University | Kim J.,Korea Institute Radiological and Science
IEEE Nuclear Science Symposium Conference Record | Year: 2012

We investigated optimized collimator designs for I-131 high energy gamma ray imaging on small animal gamma camera. The simulated structures of the pinhole collimator were evaluated by sensitivity, true, scatter and penetration count rates, and spatial resolution. The parameters, which were pinhole diameter, acceptance angle, and aperture thickness, were determined to improve image resolution with geometric conditions. In this study we showed optimized pinhole design for high energy I-131 imaging to meet the tradeoff between sensitivity and resolution. © 2011 IEEE.


Lee Y.S.,Korea Institute Radiological and science | Lee Y.S.,Yonsei University | Kim J.S.,Korea Institute Radiological and science | Kim H.-J.,Yonsei University | And 6 more authors.
IEEE Transactions on Nuclear Science | Year: 2013

124I has a complex decay scheme with high gamma energy and low positron abundance. In this study, comparative performance measurements of 124I were performed in terms of spatial resolution, sensitivity, and image quality. All measurements were performed using both 2D and 3D PET in both brain mode and whole body mode. The transverse and axial spatial resolutions at 1 cm were 5.56 and 6.07 mm for 124I, and were 4.58 and 4.77 mm and for 18F, respectively. Sensitivities were 0.5 kcps/MBq (2D) and 3.4 kcps/MBq (3D) for 124I, and 1.8 kcps/MBq (2D) and 9.8 kcps/MBq (3D) for 18F. The %contrast of 3D was higher than that of 2D in 124I. For 124 I PET imaging, 3D acquisition with brain mode was highest achievable imaging acquisition mode with finer spatial resolution and higher contrast. This result will be useful for 124 I PET imaging © 1963-2012 IEEE.


Lee Y.S.,Korea Institute Radiological and Science | Lee Y.S.,Yonsei University | Kim J.S.,Korea Institute Radiological and Science | Kim K.M.,Korea Institute Radiological and Science | And 2 more authors.
IEEE Nuclear Science Symposium Conference Record | Year: 2012

Radioimmunotherapy (RIT) is a promising approach for targeted therapy to treat intractable cancer because radionuclides are delivered more selective to tumor using monoclonal antibody, RIT can be used clinical practice with administration of murine anti-CD20. In this study, the absorbed dose of total body and red marrow of patient enrolled in RIT study was calculated. © 2011 IEEE.


Lee Y.S.,Korea Institute Radiological and Science | Lee Y.S.,Yonsei University | Kim J.S.,Korea Institute Radiological and Science | Kim K.M.,Korea Institute Radiological and Science | And 2 more authors.
IEEE Nuclear Science Symposium Conference Record | Year: 2012

Gamma camera imaging is one of prevalent diagnostic imaging tool for nuclear medicine. Although gamma camera imaging widely used for diagnostic imaging, quantification of gamma camera imaging is difficult due to scattered radiation. Compton scattering is always a problematic phenomenon in gamma camera imaging. In previous study, Siemens symbia scintillation camera was modeled for assessment of septal penetration photons and validation of Monte Carlo simulation code for the Siemens scintillation camera. In this study, optimal energy window for triple energy window (TEW) scatter correction method was assessed in gamma camera for 99mTc, 131I radioisotopes using GATE simulation. © 2011 IEEE.

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