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Bathula B.P.,Konaseema Institute of Medical science and Research Foundation
The Indian journal of chest diseases & allied sciences | Year: 2012

A 12-year-old male child suffering from pain, redness, blurring and watering of right eye since six months was diagnosed as suffering from nodular episcleritis probably tuberculosis. Diagnosis was supported by the additional finding of enlarged cervical lymph node found on aspiration cytology. Complete resolution occurred after anti-tuberculosis therapy. Source


Peshattiwar P.D.,Konaseema Institute of Medical science and Research Foundation | Peerapur B.V.,BLDEUs Shri B M Patil Medical College
Journal of Clinical and Diagnostic Research | Year: 2011

Purpose: The present study was undertaken to detect the extended spectrum β lactamases (ESBL) and metallo β lactamases (MBL) in isolates of Pseudomonas aeruginosa which were isolated from wound infections and to evaluate their susceptibility patterns. Materials and Methods: One hundred and twenty six isolates of P.aeruginosa were analyzed to study their sensitivity patterns. The presence of the ESBL enzyme was detected by the Phenotypic confirmatory test and the MBL enzyme was detected by the Imipenem - EDTA Double Disk Synergy test. Result: Out of 126 isolates of P.aeruginosa, 28 (22.22%) were ESBL producers and 10 (7.8%) were MBL producers. None of the isolates showed the coexistence of ESBL and MBL in the same isolate. All the ESBL producing isolates were sensitive to Imipenem, while the MBL producing isolates showed widespread resistance to aminoglycosides, ciprofloxacin and the piperacillin with tazobactum combination. Conclusion: The present study underlines the unique problem that the presence of ESBL has led to the widespread use of Imipenem, but that the emergence of MBLs and their broad spectrums and unrivalled drug resistance is creating a therapeutic challenge for clinicians and microbiologists. Hence, we suggest that the detection of ESBL and MBL in Pseudomonas aeruginosa should be a routine practice. We recommend a routine surveillance on antibiotic resistance in the hospital. Source


Badave G.K.,Konaseema Institute of Medical science and Research Foundation | Dhananjay K.,Konaseema Institute of Medical science and Research Foundation
Journal of Clinical and Diagnostic Research | Year: 2015

Aim: To study the quantitative method for biofilm formation and examine the correlation between biofilm formation and antibiotic resistance among the clinical isolates of Acinetobacter baumannii.Results: Forty five (62.5%) of 72 isolates produced biofilm. Resistance to ampicillin-sulbactam was least. 36.1% isolates were resistant to imipenem, 66.6% to ceftazidime, 72.2% to ciprofloxacin, 80.5% to amikacin and 84.7% to piperacillin. Biofilm formers showed greater resistance to ampicillin- sulbactam, amikacin, ciprofloxacin and ceftazidime as compared to imipenem and piperacillin. In all 65 (90.3%) isolates showed multiple drug resistance. Correlation between multidrug resistance and biofilm formation was analysed statistically and p-value was found to be significant (p-value =0.0004; p-value < 0.05 is significant by Chi – Square Test).Materials and Methods: A total of 72 A. baumannii isolates from different clinical specimens were processed and confirmed by conventional microbiological methods. Antimicrobial susceptibility testing was performed by Kirby Bauer disc diffusion method using six antibiotics. Biofilm formation was studied by microtitre plate assay.Conclusion: The study concludes that there a positive correlation between biofilm formation and multiple drug resistance in A. baumannii. © 2015, Journal of Clinical and Diagnostic Research. All rights reserved. Source


Ashok R.,King Faisal Specialist Hospital And Research Center | Suguneswari G.,Konaseema Institute of Medical science and Research Foundation | Satish K.,Konaseema Institute of Medical science and Research Foundation | Kesavaram V.,Konaseema Institute of Medical science and Research Foundation
Shiraz E Medical Journal | Year: 2013

Background: The public health impact of parasitic infection has been consistently underestimated in the past, but there is now a general consensus that diseases caused by intestinal parasites represent an important public health problem, especially children. Recent studies suggest that even moderate intensity of infection may have adverse effects on growth, iron deficiency anemia and cognitive function, practically for children of school age. Objective: Aim of the present study was to determine the intestinal parasitic infection in school going children. Materials and Methods: The stool samples were collected from different municipal school in and around Amalapuram according to the standard procedures between June 2006 to August 2006. All the stool samples were examined by the direct microscopic examination and by the formalin-ether concentration methods. Analysis of the data was carried out by using Epi info software. Results: A total 208 stool specimen were collected. The mean age group was 8.8 ± 2.11. 133 (63.9%) were infected with one or more intestinal parasites. 95 (71.4%) of the students were infected with single parasite, 38 (28.6%) with two or more parasites. The most common was Entamoeba histolytica (E.histolytica) with 41 (30.8%) single and 26 (19.54%) with multiple infections. The second most common was Giardia intestinalis (G.intestinalis) with 25 (18.8%) single and 25 (18.8%) with multiple infections. The third one was Entamoeba coli (E.coli) with 15 (11.3%) single and 17 (12.78%) with multiple infections. E.histolytica and G.intestinalis were the most commonly found parasite in multiple infections. 1.5% of Ascaris lumbricoides, 5.3% Hookworm, 0.8% Enterobius vermicularis and 0.8% of Trichuris trichuria were found in the stool sample. Conclusions: Intestinal parasitic infection is an important public health problem in Andhra Pradesh, India. Rural residence, mother education less than primary school and no hand wash with soap after toilets were the significant risk factors. Interventions including health education on personal hygiene, appropriate water management like boiling and use of latrines to the school children and to the parents.The public health impact of parasitic infection has been consistently underestimated in the past, but there is now a general consensus that diseases caused by intestinal parasites represent an important public health problem, especially children. Recent studies suggest that even moderate intensity of infection may have adverse effects on growth, iron deficiency anemia and cognitive function, practically for children of school age. © 2013, Docs Corp. Source


Beeraka C.,Konaseema Institute of Medical science and Research Foundation | Surapaneni S.,Konaseema Institute of Medical science and Research Foundation | Raavi R.,Konaseema Institute of Medical science and Research Foundation
Journal of Clinical and Diagnostic Research | Year: 2012

Introduction: Inguinal hernia repair is one of the most commonly performed surgeries in the world. Inguinal hernia accounts for 75% of all the abdominal wall hernias, with a life time risk of 27% in men and 3% in women [1]. The recurrences which follow inguinal hernia repair are of a signifcant problem. As the pathogenesis of adult inguinal hernia is a defect in the metabolism of collagen, leading to a weakening in the fascia transversalis, the use of such a weakened tissue is problematic for the hernia repair. This study was conducted in the Konaseema Institute of Medical Sciences, Amalapuram, in a rural area of Andhra Pradesh, to determine the usefulness of a polypropylene mesh for tension free repair in terms of patient comfort, affordability, return to normal activity and post operative follow up. Materials and Methods: A prospective study was conducted from April 2008-March 2009, with a follow up of 2 years, for recurrence and any other morbidity.100 Lichtsenstein tension free hernioplasties for inguinal hernia were performed by using a polypropylene mesh between. Results: The inguinal hernia was right sided in 54 cases and 28 cases had left sided hernia, while 18 were bilateral hernias. Out of these, 57 were indirect and 43 were direct hernias. The average duration of the surgery was 45 minutes, the duration of the stay in the hospital was 4 days and after a follow up for 2 years, there was no evidence of recurrence, post-operative neuralgia, delayed rejection of the mesh or testicular swelling. 2 cases had superfcial wound infections. Conclusion: Lichtenstein tension free repair with a prolene mesh is an excellent approach in the management of inguinal hernia, with encouraging results in places where Laparoscopic TEP and TAPP are not within the reach of most of the patients in terms of affordability. Source

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