Konaseema Institute of Medical science

Kākināda, India

Konaseema Institute of Medical science

Kākināda, India

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Vupputuri M.,Konaseema Institute of Medical science | Vupputuri M.,GIDE Hospital | Kandepu M.,Rangaraya Medical College | Devireddy H.R.,Devireddy Diabetes and Hormone Center
Indian Journal of Pediatrics | Year: 2014

5α-reductase (5α-R) deficiency is an important cause of ambiguious genitalia in genetic males; however therapeutic experience in literature is limited. In this report authors describe a child with 46 XY Disorder of Sexual Differentiation (DSD), due to 5α-reductase deficiency, who was managed with Dihydrotestosterone (DHT) gel. © 2013 Dr. K C Chaudhuri Foundation.


Peshattiwar P.,Konaseema Institute of Medical science
Journal of Clinical and Diagnostic Research | Year: 2012

Purpose: The interpretation of the Widal test depends upon the baseline titre which is prevalent amongst healthy individuals in a particular geographical area. Hence, this study was undertaken to determine the baseline Widal titre (titre of the antibodies to the O and H antigens of S. typhi and the H antigens of S. paratyphi A and B) amongst apparently healthy individuals in Amlapuram, Andhra Pradesh, India. Materials and Methods: Blood samples were collected from healthy blood donors (n= 490) who attended our blood bank from September 2011 to Nov 2011. The Widal tube agglutination test was carried out. 0.4 ml of two fold serially diluted patients' sera (dilutions from 1:20 to 1:320) in 0.9% normal saline was tested by adding an equal amount of antigen. Results: Of the 490 serum samples which were tested, 270 serum samples were positive for agglutinins (1 ≥ in 20) and 220 serum samples were negative for agglutinins (1 ≤ in 20). However, 96% samples showed a titre which was equal to or less than 1 in 40 to the O antigen and 91% samples had a titre which was equal to or less than 1 in 40 to the H antigen of Salmonella enterica serovar typhi. The baseline titre for the O and H antibodies of S. typhi was found to be 1: 40. The baseline titre for the Salmonella enterica serovar paratyphi A 'H' antigen was found to be ≤ 1:40 in all the 15 samples. Conclusion: Based upon the results of our study, it has been recommended that the significant titre of the 'H' agglutinins and the 'O' agglutinins of Salmonella enterica serotype typhi was ≥ 1: 80. While the significant titre of the 'H' agglutinins of Salmonella enterica serotype paratyphi A was ≥ 1: 40, the significant titre of the 'H' agglutinins of Salmonella enterica serotype paratyphi B was ≥ 1: 20.


Das S.K.,Konaseema Institute of Medical science | Maharana S.S.,Konaseema Institute of Medical science | Subudhi M.,Konaseema Institute of Medical science | Subha Rao P.V.,Konaseema Institute of Medical science
Journal of Clinical and Diagnostic Research | Year: 2013

The limb-body wall complex defects a form of amniotic band syndrome which consists of a polymal formation with a thoracic and /or an abdominal-schisis, eventration of the internal organ and anomalies of the extremities. We are presenting a case of a limb-body wall complex defect with the phenotype of a placenta-abdominal attachment, anomalies of the abdominal wall defect, absence of the right lower limb and genitourinary defects.


Padmaja R.,Konaseema institute of Medical science | Gande S.K.P.C.,Konaseema Institute of Medical science
Journal of Clinical and Diagnostic Research | Year: 2015

Acute dyspnea with pulmonary oedema in postpartum is uncommon but life-threatening event. Contributing factors for pulmonary oedema include, administration of tocolytics, underlying cardiac disease, iatrogenic fluid overload and preeclampsia acounting 0.08% of pregnancies. Pulmonary embolism, amniotic fluid embolism, pneumonia, aspiration and pulmonary oedema are some of the potentially devastating conditions that should be considered by the attending physician. Here, we report a case of postpartum acute pulmonary oedema referred to causality after an emergency caesarean section in a private hospital. No matter what the underlying pathology, prompt administration and appropriate resuscitation is always the first priority. Only after the patient has been stabilized attention must be turned to diagnosis and specific treatment. A diagnosis of severe Mitral Stenosis, probably of rheumatic origin was made after stabilizing the patient. © 2015, Journal of Clinical and Diagnostic Research. All rights reserved.


Swamy G.G.,Konaseema Institute of Medical science
Nepal Medical College journal : NMCJ | Year: 2011

To evaluate the accuracy and efficacy of fine needle aspiration cytology (FNAC) in the diagnosis of Thyroid gland enlargements. A retrospective analysis was done at Department of Pathology, Government Medical College and General Hospital, Anantapur, Andhra Pradesh, India. One hundred and fifty cases were included in this study. However in 10 cases aspirate was unsatisfactory and in 20 cases surgery was not performed and these cases were excluded from study. A total of 120 cases included in the final study. Detailed history, physical examination, routine investigations and other details of 120 patients were collected. FNAC with minimum two passes were performed in each case. Staining done with Haematoxylin and Eosin stain and Papanicolaou stains. FNAC smears and histopathology slides were reviewed. Among 120 cases 100 (83.66%) were reported cytologically as benign and 20 (16.66%) were malignant. But histologically 98 (81.66%) were benign and 22 (18.33%) were malignant. Commonest benign lesion of thyroid in both cytology and histology was nodular colloid goiter. Follicular adenoma was the second commonest one. Among malignant conditions papillary carcinoma was the commonest one in our FNAC samples, follicular carcinoma was the commonest in our histopathology samples. Four cases of false positive and 6 cases of false negative were observed. Sampling errors were mainly responsible for these false negative diagnoses. FNAC showed an accuracy of 96.6%, sensitivity 75%, specificity 95.83%, positive predicative value (PPV) 81.81% and negative predicative value (NPV) of 93.81%. Our results were similar to other international studies and suggest that FNAC is more specific and sensitive in detecting thyroid malignancy. Therefore its useas a reliable diagnostic test cannot be over emphasized. FNAC is an accurate and reliable diagnostic tool to evaluate the cause of Thyroid gland enlargements provided strict adherence to adequacy criteria are maintained.


Swamy G.G.,Konaseema Institute of Medical science
Nepal Medical College journal : NMCJ | Year: 2010

Ovarian neoplasms have become increasingly important not only because of the large variety of neoplastic entities but more because they have gradually increased the mortality rate due to female genital cancers. A total of 120 cases of ovarian tumors were studied at the Department of Pathology, Konaseema Institute of Medical Sciences, Amalapuram, India, during the period of March 2005 to March 2010, to find out frequency of different histological patterns of ovarian tumors at Konaseema Region. Among 120 cases, majority 86 (71.6%) were benign, but alarming number 30 (25.0%) were malignant, remaining 4 cases were borderline. The commonest histological pattern observed in the study was epithelial tumors (61.6%). The commonest benign tumor was serous cyst adenoma, while; the commonest malignant tumors were granulosa cell tumor and endometrial carcinoma. Epithelial tumors were commonest variety of ovarian tumors followed by germ cell tumors. A relatively high number of malignancies were observed in this study.


Vadapalli S.,Konaseema Institute of Medical Science
Journal of Clinical and Diagnostic Research | Year: 2013

Post injection fibrosis leading to muscle contracture is a known complication. Deltoid fibrosis is known to occur following trauma or an intramuscular injection. Idiopathic Deltoid fibrosis leading to abduction contracture and anterior dislocation of the shoulder is a rare entity. Prompt diagnosis and surgery by distal release of fibro-sed Deltoid muscle will lead to good functional recovery.


Lad U.P.,Konaseema Institute of Medical science | Satyanarayana P.,Konaseema Institute of Medical science | Shisode-Lad S.,MKC Government Medical College | Siri C.C.,Konaseema Institute of Medical science | Ratna Kumari N.,Konaseema Institute of Medical science
Journal of Clinical and Diagnostic Research | Year: 2013

Introduction: The handgrip strength and endurance have evolved as an important tool for the assessment of the nutritional status and as a marker of the muscle quality. In underweight as well as overweight individuals, there is the possibility of a change in the muscle quality. So, we undertook this study to find out the correlation between the BMI, the Body Fat percentage and the Hand grip strength and endurance. Materials and Methods: One hundered eighty students in three BMI ranges- underweight (BMI≤ 18.49), normal weight (BMI- 18.5- 24.99) and overweight (25-29.99) were included according to the WHO guidelines. The body fat percentage was measured by using a bioelectric impedance. The handgrip strength and the handgrip endurance were recorded by using an INCO handgrip dynamometer. The statistical correlation was done by using ANOVA. Results: In males, the handgrip endurance was better in normal weight individuals, but among the females, the underweight females had a better handgrip endurance, but the difference was statistically insignificant (p>0.05). In both males and females, there was a statistically significant difference in the handgrip endurance, with the maximum grip endurance in the normal weight group and the minimum grip endurance in the overweight group (p< 0.05). The correlation between the BMI, the body fat percentage and the handgrip endurance was complex and different for males and females. Conclusion: The underweight and overweight groups had a lower grip strength and endurance than the normal weight group in males, but not in females. The correlation was weak and it suggested that on both sides of the normal BMI, the hand grip endurance tended to decrease in males as well as in females. The increase in the body fat percentage might decrease the handgrip endurance but not the handgrip strength.


Surapaneni S.,Konaseema Institute of Medical science | Rajkumar S.,Konaseema Institute of Medical science | Vijaya Bhaskar Reddy A.,Konaseema Institute of Medical science
Journal of Clinical and Diagnostic Research | Year: 2013

Objective: To find out the significance of the Perforation-Operation Interval (POI) with respect to an early prognosis, in patients with peritonitis which is caused by peptic ulcer perforation. Study Design: Case series. Place and Duration of the Study: Department of General Surgery, Konaseema Institute of Medical Sciences and RF Amalapuram, Andhra Pradesh, India from 2008-2011. Materials and Method: This study included 150 patients with generalized peritonitis, who were diagnosed to have Perforated Peptic Ulcers (PPUs). The diagnosis of the PPUs was established on the basis of the history, the clinical examination and the radiological findings. The perforation-operation interval was calculated from the time of onset of the symptoms like severe abdominal pain or vomiting till the time the patient was operated. Result: Out of the 150 patients 134 were males and 16 were females, with a male: female ratio of 9:1. Their ages ranged between 25-70 years. Out of the 150 patients, 65 patients (43.3%) presented within 24 hours of the onset of severe abdominal pain (Group A), 27 patients (18%) presented between 24-48 hours of the onset of severe abdominal pain (Group B) and 58 patients (38.6%) presented after 48 hours. There was no mortality in Group A and the morbidity was more in Group B and Group C. There were 15 deaths in Group C. Conclusion: The problem of peptic ulcer perforation with its complication, can be decreased by decreasing the perforation -operation time interval, which as per our study, appeared to be the single most important mortality and morbidity indicator in peptic ulcer perforation.


PubMed | Konaseema Institute of Medical science and Rangaraya Medical College
Type: Journal Article | Journal: Journal of orthopaedic case reports | Year: 2017

Post traumatic hip dislocations are very rare in children. Neglected anterior hip dislocations in children are not described in literature so far. Here, we present a case of 6 weeks old anterior hip dislocation successfully managed by open reduction.A 9-year-old male child presented with neglected anterior hip dislocation on left side. Open reduction carried out through direct anterior approach to hip. Congruent reduction is achieved. At final follow up of 1 year, the child had unrestricted activities of daily living and no radiological signs of osteonecrosis or any joint space reduction.There is paucity of literature over neglected post traumatic anterior hip dislocations in children. The treatment options vary from closed reduction after heavy traction to sub trochanteric osteotomy. However, we feel that open reduction through direct anterior approach is the preferred mode of management whenever considered possible.

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