Kohjin Co.

Saiki, Japan

Kohjin Co.

Saiki, Japan
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Hashimoto C.,Niihama National College of Technology | Nagamoto A.,Kohjin Co. | Maruyama T.,Kohjin Co. | Kariyama N.,Kwansei Gakuin University | And 3 more authors.
Macromolecules | Year: 2013

The coil-to-globule transition of poly(N-isopropylacrylamide) (PNiPA) and poly(N,N-diethylacrylamide) (PdEA) in aqueous solutions has recently received substantial interest in its drastic change in the hydration state from a hydrated random coil to a hydrophobic globule for practical applications: drug delivery and tissue engineering. In this report, the hydration states of PNiPA and PdEA in aqueous solutions were investigated by IR spectroscopy in the amide I, N-H and C-H stretching band regions as compared with those of their repeat units, N-isopropylpropionamide (NiPP) and N,N-diethylpropylacrylamide (dEP) in aqueous and cyclohexane solutions in combined with their phase diagrams. The IR spectral changes in the amide I and C-H stretching band regions of N-alkylamides and N,N-dialkylamides including NiPP and dEP in aqueous solutions with varying concentration was characteristic due to different amide-amide interaction; the amide-amide interaction for N-alkylamide (C=O⋯H-N hydrogen bond) is stronger than that for N,N-dialkylamide (dipolar interaction). It is found that almost all amide groups of PNiPA in aqueous solution forms the intramolecular C=O⋯H-N hydrogen bond even in the coil state and that the amide group of PNiPA is less hydrated than that of PdEA in spite of the similar degree of hydration to alkyl groups. The IR spectral changes in the amide I and C-H stretching band regions of PNiPA and PdEA in aqueous solutions with heat are ascribed to the dehydration of the amide and alkyl groups from the coil state to the globule one. © 2013 American Chemical Society.


Patent
Kohjin Co. | Date: 2015-04-23

A natural yeast extract which is rich in glutamic acid and therefore has an impact at first taste. Further, provided is a yeast extract which is also rich in 5-guanylic acid or 5-inosinic acid and therefore has strong umami. Further, provided is a yeast mutant capable of accumulating a large amount of glutamic acid, glutamine and ribonucleic acid for obtaining such a yeast extract. A yeast mutant to which resistance to organic acids and analogues thereof has been imparted by inducing spontaneous mutation, accumulates a significant amount, i.e., 10% by weight or more of the total of free glutamic acid and glutamine in the cell, and further accumulates 5% by weight or more of a ribonucleic acid. The yeast extract produced by using this strain contains 20% by weight or more of L-glutamic acid, and further contains 3% by weight or more of 5-IG.


Patent
Kohjin Co. | Date: 2010-12-08

The present invention provides a natural yeast extract having a high-impact first taste by containing glutamic acid in a large amount. Further, the present invention provides a yeast extract having strong umami by containing 5-guanylic acid or 5-inosinic acid in a large amount. In addition, the present invention provides a yeast mutant accumulating glutamic acid, glutamine, and ribonucleic acid in a large amount for obtaining the yeast extract. A yeast mutant inducing a natural mutation to which organic acid-tolerance or organic acid analogue-tolerance is imparted accumulates free glutamic acid and glutamine in such a significant amount as a total amount of 10% by weight or more in a cell, and further accumulates ribonucleic acid in an amount of 5% by weight or more. A yeast extract produced using the above yeast mutant contains L-glutamic acid in an amount of 20% by weight or more, and further contains 5-IG in an amount of 3% by weight or more.


Patent
Kohjin Co. | Date: 2016-07-05

A natural yeast extract which is rich in glutamic acid and therefore has an impact at first taste. Further, provided is a yeast extract which is also rich in 5-guanylic acid or 5-inosinic acid and therefore has strong umami. Further, provided is a yeast mutant capable of accumulating a large amount of glutamic acid, glutamine and ribonucleic acid for obtaining such a yeast extract. A yeast mutant to which resistance to organic acids and analogues thereof has been imparted by inducing spontaneous mutation, accumulates a significant amount, i.e., 10% by weight or more of the total of free glutamic acid and glutamine in the cell, and further accumulates 5% by weight or more of a ribonucleic acid. The yeast extract produced by using this strain contains 20% by weight or more of L-glutamic acid, and further contains 3% by weight or more of 5-IG.


Trademark
KOHJIN Life science Co. and KOHJIN Co. | Date: 2010-04-06

Condiments, namely, sauces; food flavorings, other than essential oils; seasonings; yeasts; and yeast extracts.


Trademark
KOHJIN Life science Co., KOHJIN Holdings Co. and KOHJIN Co. | Date: 2010-05-11

[ Food enriching preparations, namely, Food supplements, Vitamin and mineral preparations for use as ingredients in the food and pharmaceutical industry, Dietary fiber as an additive for food products, Dietary food supplements, Nutritional additives for medical purposes for use in foods and dietary supplements for human consumption; ] food enriching preparations containing glutathione, namely, Food supplements, Vitamin and mineral preparations for use as ingredients in the food and pharmaceutical industry, Dietary fiber as an additive for food products, Dietary food supplements, Nutritional additives for medical purposes for use in foods and dietary supplements for human consumption, all of which contain glutathione; calcium supplements; nutritional additives for medical purposes, namely, [ Nutritional additives for medical purposes for use in foods and dietary supplements for human consumption, ] Nutritional additives to foodstuffs for animals * containing glutathione *, for medical purposes; medicinal tonics and substitutes therefor, namely, meal replacement drinks for use as food fillers, Medicinal drinks; and vitamin preparations * containing glutathione *.


Trademark
KOHJIN Holdings Co. and KOHJIN Co. | Date: 2012-12-25

Dietetic foods adapted for medical purposes; mineral food-supplements; vitamin preparations; yeast for pharmaceutical purposes. Seasonings; yeast; yeast extracts for food.


Trademark
KOHJIN Life science Co. and KOHJIN Co. | Date: 2012-10-30

Seasonings (other than spices); yeast extracts for food.


Trademark
KOHJIN Life science Co. and KOHJIN Co. | Date: 2011-08-02

Seasonings; yeast extracts for food.


Trademark
KOHJIN Holdings Co. and KOHJIN Co. | Date: 2011-08-23

Industrial chemicals; Industrial auxiliary fluids for use with abrasives; paper pulp. Industrial Lubricants; cutting fluids, namely, cutting oils. paper for commercial and industrial use. Plastic film for commercial and industrial use.

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