Kobe, Japan
Kobe, Japan

Kobe University , also known in the Kansai region as Shindai , is a leading national university located in Kobe, Hyōgo, Japan. It was established in 1949, but the academic origins of Kobe University trace back to the establishment of Kobe Higher Commercial School in 1902, which was renamed as Kobe University of Commerce, and Kobe University of Economics.Kobe University comprises 14 graduate schools and 11 undergraduate faculties. The university holds a total of about 16,000 students enrolled in undergraduate and graduate programs. The institution welcomes overseas students, which accounted for a total of 1,108 students, as of 2011. It also has 3,300 staff members, including professors, associate professors and administrative officials.Located beside the foothills of Mount Rokkō, the university provides a view of the city and port of Kobe, providing an environment for the pursuit of academic studies, especially social science areas. Kobe University is one of the oldest and largest national universities in Japan. It is consistently one of the highest ranking national universities in Japan that is not one of Japan's National Seven Universities.Kobe Higher Commercial School was one of the oldest institution with business and economics majors in Japan. Especially, the Graduate School of Economics benefits fully from a century of the history and the tradition. Kobe is also the first collegiate business school in Japan. Therefore, Kobe is called the birthplace of Japanese higher education in economics and business administration, and it has always been the center of Japanese business studies.Furthermore, the Graduate School of Law was also established with the legal studies section of the former Kobe University of Economics. It has become a leading institution of high academic institution in the field of legal and political studies, and has been successful in becoming a reputable academic center.The Research Institute for Economics and Business Administration, founded in 1919, has a history as a high-level research institution for international economics and international management. The Institute has been highly regarded internationally for its outstanding achievements in theoretical, historical, empirical, and quantitative research.In the meantime, Kobe Hospital was established in 1869; it was a training center for medical practitioners, which was one of the oldest institutions in the modern medical education in Japan.In 1990, they made new changes as one of the major universities specializing in graduate research and education.Under the Japanese Ministry of Education and Science, it has started a new Center of Excellence projects, the "Research and Education Center of New Japanese Economic Paradigms", "Development and Education Center for Advanced Business Systems", and "Research Center for Dynamic Legal Processes of Advanced Market Societies". Wikipedia.


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The present invention provides a method of modifying a targeted site of a double stranded DNA, including a step of contacting a complex wherein a nucleic acid sequence-recognizing module that specifically binds to a target nucleotide sequence in a selected double stranded DNA and a nucleic acid base converting enzyme are bonded, with the double stranded DNA, to convert one or more nucleotides in the targeted site to other one or more nucleotides or delete one or more nucleotides, or insert one or more nucleotides into the targeted site, without cleaving at least one chain of the double stranded DNA in the targeted site.


Patent
Kobe University and Integral Geometry Science Inc. | Date: 2017-01-18

A scattering tomography method includes: radiating waves to an object from a plurality of transmitting antenna elements aligned on a side surface of a case; receiving scattered waves by a plurality of receiving antenna elements aligned on the side surface of the case; and reconstructing an image relating to information on an interior of the object using scattered wave data representing the scattered waves received by the plurality of receiving antenna elements. In the reconstructing, a reconstruction function for reconstructing the image relating to the information on the interior of the object is set in advance for a three-dimensional space having the same shape as the case, an asymptotic equation which an asymptotic expression of the reconstruction function satisfies is constructed, a visualization function that is obtained by solving the asymptotic equation is derived from the scattered wave data, and the image relating to the information on the interior of the object is reconstructed using the visualization function.


Patent
System Instruments Co., Hirosaki University and Kobe University | Date: 2017-03-29

An automatic analyzing apparatus 10 includes a chip rack 11 that stores a pipette chip, a pipette 12 into which a specimen is injected, a conveyance unit that conveys the pipette 12 by parallel translation, a reagent rack 14, a reaction unit 15, a detection unit 16, and a detection block unit 17. The pipette chip stored by the chip rack 11 has a planar structure to directly and optically detect the specimen. The chip rack 11 includes, in a hole that receives the pipette chip, a guide corresponding to the structure of the pipette chip. The pipette 12 sucks or discharges the specimen via the pipette chip mounted onto the tip thereof by a drive of a pump. In the detection unit 16, a measurement is carried out with the pipette chip arranged so that the plane that receives light is vertical to an optical axis.


The present invention provides a method of modifying a targeted site of a double stranded DNA, including a step of contacting a complex wherein a nucleic acid sequence-recognizing module that specifically binds to a target nucleotide sequence in a selected double stranded DNA and a nucleic acid base converting enzyme are bonded, with the double stranded DNA, to convert one or more nucleotides in the targeted site to other one or more nucleotides or delete one or more nucleotides, or insert one or more nucleotides into the targeted site, without cleaving at least one chain of the double stranded DNA in the targeted site.


Provided are a glass body for pressure forming enabling press forming in a low-temperature range without the need of a special mold material, and a method for manufacturing the same. A glass body for pressure forming 1 having a porosified layer 1b formed by porosifying a surface thereof and having a Vickers hardness of 85 N/mm^(2 )or less on the porosified surface. The porosified layer 1b can be manufactured by phase-separating the glass body by spinodal decomposition, acid-treating the phase-separated glass body and then treating the acid-treated glass body with alkali or hot water to porosify the surface of the glass body.


Patent
Kobe University and Integral Geometry Science Inc. | Date: 2016-09-12

A scattering tomography method includes: radiating waves to an object from a plurality of transmitting antenna elements aligned on a side surface of a case; receiving scattered waves by a plurality of receiving antenna elements aligned on the side surface of the case; and reconstructing an image relating to information on an interior of the object using scattered wave data representing the scattered waves. In the reconstructing, a reconstruction function for reconstructing the image relating to the information on the interior of the object is set in advance for a three-dimensional space having the same shape as the case, a scattering field equation which the reconstruction function satisfies is constructed, a visualization function that is obtained by solving the scattering field equation is derived from the scattered wave data, and the image relating to the information on the interior of the object is reconstructed using the visualization function.


Patent
Kobe University, Alfresa Pharma Corporation and Kanai Juyo Kogyo Co. | Date: 2016-11-23

A radiotherapy spacer is disclosed that has both flexibility for allowing it to gently cover the organs of various shapes along their surfaces and pressure resistance for preventing itself from being crushed under the pressure between organs and thus enabling it to retain its own shape and continuously ensure the therapeutic space. The spacer comprises a fiber assembly formed of entangled biocompatible fibers, which may be bioabsorbable, such as nonwoven fabric, and is characterized in that the density of the fiber assembly is 0.05 g/cm^(3) to 0.2 g/cm^(3).


Patent
Kobe University and Nippon Kayaku Kabushiki Kaisha | Date: 2016-01-13

The purpose of the present invention is to provide an organic semiconductor thin film forming method, and an organic semiconductor device production method which uses the same. This organic semiconductor thin film production method involves a step for arranging on the substrate a mold having recesses, and a step for introducing an organic semiconductor solution into the gaps formed by the recesses and the substrate.


Furuse M.,Kobe University
Cold Spring Harbor perspectives in biology | Year: 2010

The morphological feature of tight junctions (TJs) fits well with their functions. The core of TJs is a fibril-like proteinaceous structure within the lipid bilayer, the so-called TJ strands. TJ strands in apposing plasma membranes associate with each other to eliminate the intercellular space. A network of paired TJ strands generates a continuous belt that circumscribes each cell to establish the diffusion barrier to the solutes in the paracellular pathway throughout the cellular sheet. Identification and characterization of TJ-associated proteins during the last two decades has unveiled the nature of TJ strands and how they are spatially organized. The interplay between integral membrane proteins, claudins, and cytoplasmic plaque proteins, ZO-1/ZO-2, is critical for TJ formation and function.


Aikawa Y.,Kobe University
Chemical Reviews | Year: 2013

Cores are subject to gravitational instability; they are massive enough to collapse due to their own gravity. The cores are supported against collapse by a pressure gradient due to the combination of thermal, magnetic, and turbulent pressure. The cores start collapse to form stars, once the gravity overwhelms the pressure gradient. The core before star formation is called a prestellar core, whereas the core harboring protostar(s) are called a protostellar core. Molecular line observations in radio wavelength is a very powerful tool to investigate the core structure, since millimeter radiation suffer much less attenuation than shorter wavelength. High spectral resolution of radio telescopes also enable us to investigate dynamics of the core.

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