Kobe, Japan
Kobe, Japan

Kobe University , also known in the Kansai region as Shindai , is a leading national university located in Kobe, Hyōgo, Japan. It was established in 1949, but the academic origins of Kobe University trace back to the establishment of Kobe Higher Commercial School in 1902, which was renamed as Kobe University of Commerce, and Kobe University of Economics.Kobe University comprises 14 graduate schools and 11 undergraduate faculties. The university holds a total of about 16,000 students enrolled in undergraduate and graduate programs. The institution welcomes overseas students, which accounted for a total of 1,108 students, as of 2011. It also has 3,300 staff members, including professors, associate professors and administrative officials.Located beside the foothills of Mount Rokkō, the university provides a view of the city and port of Kobe, providing an environment for the pursuit of academic studies, especially social science areas. Kobe University is one of the oldest and largest national universities in Japan. It is consistently one of the highest ranking national universities in Japan that is not one of Japan's National Seven Universities.Kobe Higher Commercial School was one of the oldest institution with business and economics majors in Japan. Especially, the Graduate School of Economics benefits fully from a century of the history and the tradition. Kobe is also the first collegiate business school in Japan. Therefore, Kobe is called the birthplace of Japanese higher education in economics and business administration, and it has always been the center of Japanese business studies.Furthermore, the Graduate School of Law was also established with the legal studies section of the former Kobe University of Economics. It has become a leading institution of high academic institution in the field of legal and political studies, and has been successful in becoming a reputable academic center.The Research Institute for Economics and Business Administration, founded in 1919, has a history as a high-level research institution for international economics and international management. The Institute has been highly regarded internationally for its outstanding achievements in theoretical, historical, empirical, and quantitative research.In the meantime, Kobe Hospital was established in 1869; it was a training center for medical practitioners, which was one of the oldest institutions in the modern medical education in Japan.In 1990, they made new changes as one of the major universities specializing in graduate research and education.Under the Japanese Ministry of Education and Science, it has started a new Center of Excellence projects, the "Research and Education Center of New Japanese Economic Paradigms", "Development and Education Center for Advanced Business Systems", and "Research Center for Dynamic Legal Processes of Advanced Market Societies". Wikipedia.


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The present invention provides a method of modifying a targeted site of a double stranded DNA, including a step of contacting a complex wherein a nucleic acid sequence-recognizing module that specifically binds to a target nucleotide sequence in a selected double stranded DNA and a nucleic acid base converting enzyme are bonded, with the double stranded DNA, to convert one or more nucleotides in the targeted site to other one or more nucleotides or delete one or more nucleotides, or insert one or more nucleotides into the targeted site, without cleaving at least one chain of the double stranded DNA in the targeted site.


Patent
Kobe University and Integral Geometry Science Inc. | Date: 2017-01-18

A scattering tomography method includes: radiating waves to an object from a plurality of transmitting antenna elements aligned on a side surface of a case; receiving scattered waves by a plurality of receiving antenna elements aligned on the side surface of the case; and reconstructing an image relating to information on an interior of the object using scattered wave data representing the scattered waves received by the plurality of receiving antenna elements. In the reconstructing, a reconstruction function for reconstructing the image relating to the information on the interior of the object is set in advance for a three-dimensional space having the same shape as the case, an asymptotic equation which an asymptotic expression of the reconstruction function satisfies is constructed, a visualization function that is obtained by solving the asymptotic equation is derived from the scattered wave data, and the image relating to the information on the interior of the object is reconstructed using the visualization function.


Patent
System Instruments Co., Hirosaki University and Kobe University | Date: 2017-03-29

An automatic analyzing apparatus 10 includes a chip rack 11 that stores a pipette chip, a pipette 12 into which a specimen is injected, a conveyance unit that conveys the pipette 12 by parallel translation, a reagent rack 14, a reaction unit 15, a detection unit 16, and a detection block unit 17. The pipette chip stored by the chip rack 11 has a planar structure to directly and optically detect the specimen. The chip rack 11 includes, in a hole that receives the pipette chip, a guide corresponding to the structure of the pipette chip. The pipette 12 sucks or discharges the specimen via the pipette chip mounted onto the tip thereof by a drive of a pump. In the detection unit 16, a measurement is carried out with the pipette chip arranged so that the plane that receives light is vertical to an optical axis.


The present invention provides a method of modifying a targeted site of a double stranded DNA, including a step of contacting a complex wherein a nucleic acid sequence-recognizing module that specifically binds to a target nucleotide sequence in a selected double stranded DNA and a nucleic acid base converting enzyme are bonded, with the double stranded DNA, to convert one or more nucleotides in the targeted site to other one or more nucleotides or delete one or more nucleotides, or insert one or more nucleotides into the targeted site, without cleaving at least one chain of the double stranded DNA in the targeted site.


News Article | May 18, 2017
Site: phys.org

The discovery was made by a joint research team led by Associate Professor TACHIKAWA Takashi (Molecular Photoscience Research Center, Kobe University) and Professor MAJIMA Tetsuro (Institute of Scientific and Industrial Research, Osaka University). Their findings were published on April 6 in the online version of Angewandte Chemie International Edition. When light is applied to photocatalysts, electrons and holes are produced on the surface of the catalyst, and hydrogen is obtained when these electrons reduce the hydrogen ions in water. However, in traditional photocatalysts the holes that are produced at the same time as the electrons mostly recombine on the surface of the catalyst and disappear, making it difficult to increase conversion efficiency. Professor Tachikawa's research group developed a photocatalyst made of mesocrystal, deliberately creating a lack of uniformity in size and arrangement of the crystals. This new photocatalyst is able to spatially separate the electrons and electron holes to prevent them recombining. As a result, it has a far more efficient conversion rate for producing hydrogen than conventional nanoparticulate photocatalysts (approximately 7 percent). The team developed a new method called "topotactic epitaxial growth" that uses the nanometer-sized spaces in mesocrystals. Based on this synthesis method they were able to synthesize strontium titanate (SrTiO3) from a compound with a different structure, titanium oxide (TiO2), using a simple one-step hydrothermal reaction. By lengthening the reaction time, they could also grow larger particles near the surface while preserving their crystalline structure. When they attached a co-catalyst to the synthesized mesocrystal and applied ultraviolet light in water, the reaction occurred with approximately 7 percent light energy conversion efficiency. Under the same conditions, SrTiO3 nanoparticles which had not been converted into mesocrystals reached a conversion efficiency of less than 1 percent, proving that the reaction efficiency increased tenfold under the mesocrystal structure. When each particle was examined under a fluorescent microscope, the team found that the electrons produced during the reaction gathered around the larger nanocrystals. When exposed to ultraviolet light, the electrons in this newly-developed photocatalyst move smoothly between the nanoparticles inside the mesocrystal, gather around the larger nanocrystals generated on the surface of the crystal, and efficiently reduce the hydrogen ions to create hydrogen. The discovery of this powerful photocatalyst started with the researchers' idea to "deliberately break down the ordered structure of mesocrystals," a concept that could be applied to other materials. The strontium titanate used this time is a cubic crystal, which means there is no variation in molecular adsorption or the reaction strength for each crystal plane. By regulating the size and spatial arrangement of the nanocrystals, which form the building blocks for this structure, it may be possible to greatly increase the light energy conversion efficiency of the existing system. Using these findings, the research group plans to apply mesocrystal technology to realizing the super-efficient production of hydrogen from solar energy. The perovskite metal oxides, including strontium titanate, the target of this study, are the fundamental materials of electronic elements, so their results could be applied to a wide range of fields. Explore further: Novel design strategy for hydrogen-generating molecular photocatalysts More information: Peng Zhang et al. Topotactic Epitaxy of SrTiOMesocrystal Superstructures with Anisotropic Construction for Efficient Overall Water Splitting, Angewandte Chemie International Edition (2017). DOI: 10.1002/anie.201702223


Patent
Asahi Kasei Corporation and Kobe University | Date: 2017-06-21

A forward osmosis membrane characterized in that a thin membrane layer having the performance of a semi-permeable membrane is laminated on a polyketone support layer.


The purpose of the present invention is to provide a device for fixing biological soft tissue, the device being composed of a magnesium-based alloy material, wherein the device is endowed with strength and deformation performance for being used as a device for coupling biological soft tissue that has been cut or separated due to an incision or the like during a surgical procedure, and is completely degraded in vivo and discharged after adhesion of the soft tissue or after healing of the incision tissue. This device, composed of a magnesium-based alloy material, is composed of a ternary Mg alloy material of Mg-Ca-Zn. In the Mg alloy material, the Ca and Zn are contained within the solid-solubility limit with respect to the Mg. The remainder is composed of Mg and unavoidable impurities. The Zn content is 0.5 at% or less. The Ca and Zn content has a relationship of Ca:Zn=1:x (where x is 1 to 3) by atom ratio. The crystal grain structure is equiaxed, the crystal grain size according to linear intercept being 30 to 250 m.


Patent
Asahi Kasei Corporation and Kobe University | Date: 2015-08-10

A forward osmosis membrane characterized in that a thin membrane layer having the performance of a semi-permeable membrane is laminated on a polyketone support layer.


An expression vector is disclosed which contains a promoter DNA; a DNA encoding a peptide having a defined amino acid sequence and having secretion signal activity; and a DNA encoding an intended protein or a cloning site for insertion of the DNA encoding an intended protein. An expression vector is also disclosed which contains a promoter DNA; a DNA encoding any peptide having a defined amino acid sequence and having secretion signal activity; a DNA encoding an intended protein or a cloning site for insertion of the DNA encoding an intended protein; and a DNA encoding an anchor domain. The peptide having secretion signal activity allows for secretory production and cell surface display of a protein with high activity, in yeast. According to the present invention, a secretion signal peptide is provided which stably has higher secretion activity ability It is also an object of the present invention to provide a secretion signal peptide that stably has higher secretion ability than that of a conventionally used secretion signal peptide in secretory production and cell surface display of a protein.


Aikawa Y.,Kobe University
Chemical Reviews | Year: 2013

Cores are subject to gravitational instability; they are massive enough to collapse due to their own gravity. The cores are supported against collapse by a pressure gradient due to the combination of thermal, magnetic, and turbulent pressure. The cores start collapse to form stars, once the gravity overwhelms the pressure gradient. The core before star formation is called a prestellar core, whereas the core harboring protostar(s) are called a protostellar core. Molecular line observations in radio wavelength is a very powerful tool to investigate the core structure, since millimeter radiation suffer much less attenuation than shorter wavelength. High spectral resolution of radio telescopes also enable us to investigate dynamics of the core.

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