Kobe International University

www.kobe-kiu.ac.jp
Kobe-shi, Japan

Kobe International University is a private university in Kobe, Hyōgo, Japan. The predecessor of the school was founded in 1963, and it was chartered as a university in 1968. In 1995 the school relocated from its original building in Kobe and moved to a newer building on the man-made island, Rokko Island. Wikipedia.

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Imamura A.,Moriya Keiyu Hospital | Kusunoki M.,Kobe International University | Ueda S.,Astrazeneca | Hayashi N.,Astrazeneca | Imai Y.,Bristol Myers K.K
Diabetes Therapy | Year: 2013

Introduction: Dapagliflozin is an orally administered selective sodium-glucose cotransporter 2 (SGLT2) inhibitor under development for the treatment of type 2 diabetes mellitus (T2DM). Dapagliflozin lowers blood glucose through a reduction in renal glucose reabsorption. This study was performed to assess the effect of the oral antidiabetic agent voglibose [0.2 mg thrice daily (t.i.d.)] at steadystate, on the pharmacokinetics, safety and tolerability of dapagliflozin administered as a single oral dose (10 mg) to Japanese patients with T2DM. Methods: This was an open-label, multi-center, drug-drug interaction study. A single oral dose of dapagliflozin (10 mg) was administered to 22 Japanese patients with T2DM in the presence and absence of voglibose (0.2 mg t.i.d.). Serial blood samples were collected before and at regular prespecified intervals after each dapagliflozin dose to determine dapagliflozin plasma concentrations and to evaluate pharmacokinetic parameters. Based on a mixed effect analysis of variance model, including the dosing condition as a fixed effect and patients as a random effect, the ratios of geometric means of area under curve from time 0 to infinity (AUC0-inf) and maximum observed plasma concentration (Cmax) with and without voglibose were estimated along with two-sided 90% confidence intervals (CIs). Results: In Japanese patients with T2DM, the exposure to dapagliflozin following a single oral dose of dapagliflozin 10 mg was not influenced by the concomitant administration of voglibose (0.2 mg t.i.d.). The geometric ratio (90% CI) for dapagliflozin AUC0-inf with/without voglibose was 1.009 (0.954, 1.067), and for Cmax 1.040 (0.899, 1.204). The median time to Cmax (tmax) and plasma clearance of dapagliflozin were also similar between treatments. The mean half-life (t) for dapagliflozin was slightly higher when administered in combination with voglibose. Dapagliflozin 10 mg was well tolerated when administered alone and in combination with voglibose in Japanese patients with T2DM. Conclusion: The results presented here support the co-administration of dapagliflozin and voglibose without dose adjustment of either agent. © The Author(s) 2013.


Maeda N.,Hiroshima University | Urabe Y.,Hiroshima University | Murakami M.,Kobe International University | Itotani K.,Kobe International University | Kato J.,Hyogo Prefectural Rehabilitation Center
Singapore Medical Journal | Year: 2015

INTRODUCTION An observational study was carried out to estimate the strength of the relationships among balance, mobility and falls in hemiplegic stroke inpatients. The objective was to examine factors that may aid in the prediction of the likelihood of falls in stroke patients. METHODS A total of 53 stroke patients (30 male, 23 female) aged 67.0 ± 11.1 years were interviewed regarding their fall history. Physical performance was assessed using the Berg Balance Scale (BBS) and the Functional Independence Measure (FIM) scale. Variables that differed between fallers and non-fallers were identified, and a discriminant function analysis was carried out to determine the combination of variables that effectively predicted fall status. RESULTS Of the 53 stroke patients, 19 were fallers. Compared with the non-fallers, the fallers scored low on the FIM, and differed with respect to age, time from stroke onset, length of hospital stay, Brunnstrom recovery stage and admission BBS score. Discriminant analysis for predicting falls in stroke patients showed that admission BBS score was significantly related to the likelihood of falls. Moreover, discriminant analysis showed that the use of a significant BBS score to classify fallers and non-fallers had an accuracy of 81.1%. The discriminating criterion between the two groups was a score of 31 points on the BBS. CONCLUSION The results of this study suggest that BBS score is a strong predictor of falls in stroke patients. As balance is closely related to the risk of falls in hospitalised stroke patients, BBS might be useful in the prediction of falls. © 2015, Singapore Medical Association. All rights reserved.


Kamishiro Y.,Kobe International University | Serrano R.,Brown University | Serrano R.,IMDEA Madrid Institute for Advanced Studies
Mathematics of Operations Research | Year: 2011

We study information transmission in large interim quasilinear economies using the theory of the core. We concentrate on the core with respect to equilibrium blocking, a core notion in which information is transmitted endogenously within coalitions, because blocking can be understood as an equilibrium of a communication mechanism used by players in coalitions. We focus on independent replicas of the basic economy. We offer both negative and positive convergence results as a function of the complexity of the mechanisms used by coalitions. Furthermore, all of the results are robust to the relaxation of the incentive constraints. Results for ex post and signal-based replica processes are also obtained. © 2011 INFORMS.


Kaneko H.,International University of Health and Welfare | Horie J.,Kobe International University
Respiratory Care | Year: 2012

BACKGROUND: Physical assessment of breathing is an important component of physical therapy evaluations. However, there are no standardized reference values of breathing movements available for use in clinical practice. The purpose of this study was to determine the 3-dimensional distances of observational points on the thorax and abdomen during breathing in healthy subjects and to assess the effects of age, posture, and sex on breathing movements. METHODS: We studied the 3-dimensional breathing movement distances of the thorax and abdomen in 100 healthy subjects (50 males, 50 females). Breathing movements were measured with a 3-dimensional motion system during quiet and deep breathing with subjects in supine and sitting positions. Thirteen reflective markers were placed on the upper (the clavicles, 3rd ribs, and sternal angle) and lower thorax (the 8th ribs, 10th ribs, and xiphoid process) and the abdomen (upper abdomen and lateral abdomen). Range of movement in both breathing conditions was measured as the 3-dimensional distance at half respiratory cycle. Respiratory rates were calculated based on the breathing movements analyzed. One-way analysis of variance, t tests, and multiple regression were used for statistical analysis. RESULTS: The average marker distances for the thorax and abdomen during quiet breathing were less than one third of those during deep breathing. Upper thoracic movement was significantly decreased with age. There was less abdominal movement in females than in males, except during quiet breathing in the supine position. The distances between the thoracic markers were greater and those of the abdomen were less during quiet and deep breathing in the sitting position, compared with those in the supine position. CONCLUSIONS: We found that the observed breathing movements were related to the effects of age, sex, and posture. These findings are in agreement with those reported in previous studies. The results may be helpful in assessing breathing movement by physical examination. © 2012 Daedalus Enterprises.


Kokado A.,Kobe International University | Saito T.,Kwansei Gakuin University
Physical Review D - Particles, Fields, Gravitation and Cosmology | Year: 2015

In the left-right symmetric model neutral gauge fields are characterized by three mixing angles θ12,θ23,θ13 between three gauge fields Bμ,WLμ3,WRμ3, which produce mass eigenstates Aμ,Zμ,Zμ′, when G=SU(2)L×SU(2)R×U(1)B-L×D is spontaneously broken down until U(1)em. We find a new mixing angle θ′, which corresponds to the Weinberg angle θW in the standard model with the SU(2)L×U(1)Y gauge symmetry, from these mixing angles. It is then shown that any mixing angle θij can be expressed by ∈ and θ′, where ∈=gL/gR is a ratio of running left-right gauge coupling strengths. We observe that light gauge bosons are described by θ′ only, whereas heavy gauge bosons are described by two parameters ∈ and θ′. © 2015 American Physical Society.


Kokado A.,Kobe International University | Saito T.,Kwansei Gakuin University
International Journal of Modern Physics A | Year: 2015

In a warped 6D world with an extra two-dimensional sphere, we propose an exactly solvable model for fermion masses with zero mode. The warp factor is given by φ(θ, φ) = sin θcos φ, which is a solution to the 6D Einstein equation with the bulk cosmological constant Λ and the energy-momentum tensor of the bulk matter fields. Our model provides another possibility of obtaining fermion zero mode, rather than traditional model based on Dirac's monopole. © 2015 World Scientific Publishing Company.


Hiramatsu R.,Kobe International University
Journal of the Japan Research Association for Textile End-Uses | Year: 2012

Cosmetics are used for face and body directly. Therefore using of cosmetics may cause allergies to people. The consumers have been attacked by lead poisoning and melanodermia (dark skin damage caused by increased deposits of melatonin) historically by using of cosmetics. Economic activities of a company were given priority over the communications with consumers. Information on reporting and close attention to consumers has been very poor. How should a company communicate with consumers and society, and perform its economic activities? In addition, how should consumers accept the products and information that a company provides? In this study, the author introduces lead poisoning caused by cosmetics and considers the melanodermia as an example. © 2012 Jpn.Res. Assn.Text.End-Uses.


Tsuji Y.,Kobe International University
Journal of the Japan Research Association for Textile End-Uses | Year: 2012

Recently, the word, "Corporate Social Responsibility" (henceforth referred to as "CSR"), has become a common phrase in newspapers and on TV. Therefore, the author has surveyed the image of CSR considered by students. Consequently, only 6.6% of university students could explain the word, "CSR". When asked abut what their image of CSR was, examples such as "not doing injustice", "giving support during times of disaster," or "protecting the environment" etc. were often given. The following results were obtained: 5.0% of the students had both heard and knew the contents of the word; 12.5% had heard the word and knew the meaning but did not know the contents; 33.0% had heard the word but did not know the meaning! 49.5% had not heard the word before. In addition, it was found that university students, particularly in regards to the medical and cosmetic industries, desire products of value or service offers and social action; however, according to the results there were few desires in regards to trading companies. In the future, CSR needs to be taught at educational institutions. On top of understanding the meaning of CSR, we must aim to increase the number of youth who can propose what to do about it. As the results of these surveys, we must teach CSR to students in educational facilities. Also, they should learn many concrete examples from companies in order to practice CSR in their immediate circle. The young need to consider CSR because they are consumers and they will be members of companies. © 2012 Jpn.Res.Assn.Text.End-Uses.


Tsuji Y.,Kobe International University
Journal of the Japan Research Association for Textile End-Uses | Year: 2013

This report compares consumers' consciousness and action between before and after the 3.11 (Eastern Japan district) great earthquake disaster. College students living in the Kansai region were set as the investigation target. The examination was performed by questionnaire. They had the consciousness in preparation for the future and perception of "Eco". Now, they come to buy only required products as compared with before the earthquake disaster. Moreover, they quit to buy disposable products, too. The result of not buying in particular accessories or expensive articles was obtained. They come to purchase smaller and lighter products. Specifically, miscellaneous goods are popular with the college students. Their purchasing miscellaneous goods increased rather than before the earthquake disaster. © 2013 Jpn. Res. Assn. Text. End-Uses.


Tsuji Y.,Kobe International University
Journal of the Japan Research Association for Textile End-Uses | Year: 2014

All over Japan, "Mascot Characters" exist and are based on some special products of a region, culture, history or other outstanding feature to attract people. Whenever these characters appear live (with people wearing full-size character costumes to animate them) at tourist sites or special events, they are instantly surrounded by crowds surging forward, exclaiming "kawaii! (how cute!)" and scrambling to have their pictures taken with characters. In this report, a survey was conducted focusing on which "Mascot Character" is popular among university students. Two mascot characters, "Hikonyan" and "Kumamon ", were highly recognized and also the favorites of university students. This survey revealed that Hikonyan is popular because is cute and friendly. Kumamon is popular for more reasons apart from being cute and friendly, is easy to recognize, lovely, attractive, when people see him makes them feel better, etc. The main cause of the feeling "Cute" are the tone of the colors (e.g. white, yellow, etc.), the round shape and also the shape of the animal, etc. The girls have more possession of mascot character goods than boys, from these results we can consider that "Mascot Characters" were created from the girl's perspective and thinking about them. ©2014 Jpn. Res. Assn. Text End-Uses.

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