KNR Systems Inc. | Date: 2014-12-06
Hydraulic rotary actuator according to the present invention disposes entry and exit lines of the hydraulic fluid within the hydraulic rotary actuator and comprises a floating member with a hollow portion, a rotating member configured to be inserted into the hollow portion, a working fluid supplied to said hollow portion, a servo control valve connected to said floating member configured to control the flow rate, an entry line connected to said servo control valve and further connecting said servo control valve to said floating member, said entry line forming a through-hole that penetrates through said floating member and forming a supply passage for said working fluid, an exit line connecting said hollow portion to said servo control valve and further thereon to outside of floating member, said exit line forming a through-hole that penetrates through said floating member and forming a discharge passage for said working fluid.
Knr Systems Inc. | Date: 2015-08-10
An apparatus and method for extracting particles are provided. The particle extraction apparatus includes: a main body; a support unit provided in the main body and in which a sample plate is disposed; an extraction unit that can be selectively submerged in a sample of the sample plate and that extracts particles within the sample; a signal generator that generates an electrical signal so as to generate an electrical field within the sample within the sample plate; and a controller that controls operation of the signal generator, wherein particles within the sample are attached to the extraction unit to be extracted by an electrical field generated within the sample.
Kalyanasundaram D.,University of Washington |
Kim J.-H.,University of Washington |
Yeo W.-H.,University of Washington |
Oh K.,Nanofacture, Inc. |
And 7 more authors.
Analytical and Bioanalytical Chemistry | Year: 2013
Simple and rapid extraction of human genomic DNA remains a bottleneck for genome analysis and disease diagnosis. Current methods using microfilters require cumbersome, multiple handling steps in part because salt conditions must be controlled for attraction and elution of DNA in porous silica. We report a novel extraction method of human genomic DNA from buccal swab and saliva samples. DNA is attracted onto a gold-coated microchip by an electric field and capillary action while the captured DNA is eluted by thermal heating at 70 C. A prototype device was designed to handle four microchips, and a compatible protocol was developed. The extracted DNA using microchips was characterized by qPCR for different sample volumes, using different lengths of PCR amplicon, and nuclear and mitochondrial genes. In comparison with a commercial kit, an equivalent yield of DNA extraction was achieved with fewer steps. Room-temperature preservation for 1 month was demonstrated for captured DNA, facilitating straightforward collection, delivery, and handling of genomic DNA in an environment-friendly protocol. [Figure not available: see fulltext.] © 2013 Springer-Verlag Berlin Heidelberg. Source
Park J.J.,KNR SYSTEMS Inc. |
You W.S.,Sungkyunkwan University |
Jin S.M.,KNR SYSTEMS Inc. |
Choi H.R.,Sungkyunkwan University |
And 3 more authors.
IEEE International Conference on Automation Science and Engineering | Year: 2012
In this paper, we present a point-of-care test equipment which can afford 'flexibility', 'portability' and 'low cost'. Firstly, the system components which include reagent tray, dispensing module, microfluidic disk rotor and photometry scanner, and each of their functions are explained. Then, test results of some of diagnostic tests are included to show the reliability of the point-of-care test equipment. © 2012 IEEE. Source
La M.,Pohang University of Science and Technology |
Park S.J.,Pohang University of Science and Technology |
Kim H.W.,Pohang University of Science and Technology |
Park J.J.,KNR SYSTEMS Inc. |
And 3 more authors.
Microfluidics and Nanofluidics | Year: 2013
In this paper, a centrifugal force-based serpentine micromixer (CSM) on a plastic lab-on-A-disk (LOD) for biochemical assay was designed, fabricated, and fully characterized with numerical and experimental methods. The CSM comprised two inlets, an outlet, and a serpentine microchannel composed of five circumferential channels with connecting radial channels in one layer. The centrifugal force induced in the rotating disk thoroughly mixed the sample and reagent together throughout the serpentine microchannel of the CSM. Despite its simple geometry, effective mixing performance was achieved inside the CSM because of transverse secondary flows and the three-dimensional stirring effect in the microchannel. Numerical simulation showed that the interfaces of the two streams inside the circumferential microchannel were efficiently stirred by the induced transversal velocity field. The plastic LOD was fabricated by CNC-micromilling on one layer of the thermoplastic substrate, followed by thermal bonding with a cover plastic substrate. Mixing performance of the CSM was also investigated experimentally by means of colorimetric analysis using phenolphthalein. High levels of distributive mixings were obtained within a short required mixing length. As a proof-of-concept example, a biochemical assay of albumin level was successfully determined with the help of the LOD containing the CSM. Owing to the mass-producible simple geometry, excellent mixing performance, and convenience, the CSM can be applied to biochemical assays based on the centrifugal microfluidics. © 2012 Springer-Verlag Berlin Heidelberg. Source